English

Addition of flow reactions preserving multistationarity and bistability

Molecular Networks 2019-12-11 v2 Dynamical Systems

Abstract

We consider the question whether a chemical reaction network preserves the number and stability of its positive steady states upon inclusion of inflow and outflow reactions. Often a model of a reaction network is presented without inflows and outflows, while in fact some of the species might be degraded or leaked to the environment, or be synthesized or transported into the system. We provide a sufficient and easy-to-check criterion based on the stoichiometry of the reaction network alone and discuss examples from systems biology.

Keywords

Cite

@article{arxiv.1909.11940,
  title  = {Addition of flow reactions preserving multistationarity and bistability},
  author = {Daniele Cappelletti and Elisenda Feliu and Carsten Wiuf},
  journal= {arXiv preprint arXiv:1909.11940},
  year   = {2019}
}

Comments

To appear in Mathematical Biosciences