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Chronic wounds represent a major public health problem affecting 6.5 million people in the United States. Ischemia represents a serious complicating factor in wound healing. In this paper we analyze a recently developed mathematical model…
We study the asymptotics of large directed graphs, constrained to have certain densities of edges and/or outward $p$-stars. Our models are close cousins of exponential random graph models (ERGMs), in which edges and certain other subgraph…
We analyze the asymptotic stability of a nonlinear system of two differential equations with delay describing the dynamics of blood cell production. This process takes place in the bone marrow where stem cells differentiate throughout…
Coronary heart disease is a common cause of death despite being preventable. To treat the underlying plaque deposits in the arterial walls, intravascular optical coherence tomography can be used by experts to detect and characterize the…
We consider two-parameter bifurcation of equilibrium states of an elastic rod on a deformable foundation. Our main theorem shows that bifurcation occurs if and only if the linearization of our problem has nontrivial solutions. In fact our…
In this work we analyse a PDE-ODE problem modelling the evolution of a Glioblastoma, which includes an anisotropic nonlinear diffusion term with a diffusion velocity increasing with respect to vasculature. First, we prove the existence of…
Hypertension is one of the most common age-related chronic diseases and by predisposing individuals for heart failure, stroke and kidney disease, it is a major source of morbidity and mortality. Its etiology remains enigmatic despite…
In the first part of this paper we review a mathematical model for the onset and progression of Alzheimer's disease (AD) that was developed in subsequent steps over several years. The model is meant to describe the evolution of AD in vivo.…
We study first-passage percolation where edges in the left and right half-planes are assigned values according to different distributions. We show that the asymptotic growth of the resulting inhomogeneous first-passage process obeys a shape…
We develop an athermal shear-transformation-zone (STZ) theory of plastic deformation in spatially inhomogeneous, amorphous solids. Our ultimate goal is to describe the dynamics of the boundaries of voids or cracks in such systems when they…
A horizontal $N$-dimensional plane, having a diffusion of its own, exchanges with the lower half space. There, a reaction-diffusion process, modelled by a free boundary problem, takes place. We wish to understand whether, and how, the free…
The flapping flag instability occurs when a flexible cantilevered plate is immersed in a uniform airflow. To this day, the nonlinear aspects of this aeroelastic instability are largely unknown. In particular, experiments in the literature…
Coronary heart disease (CHD) remains a top reason of mortality worldwide. This study introduces a novel approach by integrating patient-specific Multi-slice CT scans into CAD models and employing a one-dimensional numerical framework to…
Building on the striking similarity between the structure of the spindle during mitosis in living cells and nematic textures in confined liquid crystals, we use a continuum model of two-dimensional nematic liquid crystal droplets, to…
We study bifurcation from a branch of trivial solutions of semilinear elliptic Dirichlet boundary value problems on a geodesic ball, whose radius is used as the bifurcation parameter. In the proof of our main theorem we obtain in addition a…
The phase behavior of a model suspension of colloidal polydisperse platelets is studied using density-functional theory. Platelets are modelled as parallel rectangular prisms of square section $l$ and height $h$, with length and height…
In this work, we consider a certain multilayered (thick layer) wave--(thin layer) wave--heat (fluid) interactive PDE system. Such coupled PDE systems have been used in the literature to describe the blood transport process in mammalian…
The goal of this work is to explain an unexpected feature of the expanding level sets of the solutions of a system where a half plane, in which reaction-diusion phenomena take place, exchanges mass with a line having a large diusion of its…
We consider a nonlinear singularly perturbed PDE leaning on a complex perturbation parameter $\epsilon$. The problem possesses an irregular singularity in time at the origin and involves a set of so-called moving turning points merging to 0…
Alzheimer's disease is not the outcome of a single cause but the convergence of many. This review reframes dementia as a systemic failure, where amyloid plaques and tau tangles are not root causes but late-stage byproducts of the underlying…