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We present here a population structured model to describe the dynamics of macrophage cells. The model involves the interactions between modified LDL, monocytes/macrophages, cytokines and foam cells. The key assumption is that the individual…

Analysis of PDEs · Mathematics 2017-03-31 Nicolas Meunier , Nicolas Muller

Atherosclerosis, a chronic lesion of vascular wall, remains a leading cause of death and loss of life years. Classical hypotheses for atherosclerosis are long-standing mainly to explain atherogenesis. Unfortunately, these hypotheses may not…

Tissues and Organs · Quantitative Biology 2020-10-22 Xinggang Wang , Aijun Sun , Junbo Ge

A considerable number of research works has been devoted to the study of tumor models. Several biophysical factors, such as cell proliferation, apoptosis, chemotaxis, angiogenesis and necrosis, have been discovered to have an impact on the…

Analysis of PDEs · Mathematics 2022-12-14 Min-Jhe Lu , Wenrui Hao , Bei Hu , Shuwang Li

In the current manuscript, a first two-patch model with Allee effect and nonlinear dispersal is presented. We study both the ODE case and the PDE case here. In the ODE model, the stability of the equilibrium points and the existence of…

Dynamical Systems · Mathematics 2023-10-17 Yue Xia , Lijuan Chen , Vaibhava Srivastava , Rana D. Parshad

Free boundary problems are those described by PDEs that exhibit a priori unknown (free) interfaces or boundaries. These problems appear in Physics, Probability, Biology, Finance, or Industry, and the study of solutions and free boundaries…

Analysis of PDEs · Mathematics 2017-07-05 Xavier Ros-Oton

In the absence of external material deposition, crystal surfaces usually relax to become flat by decreasing their free energy. We study an asymmetry in the relaxation of macroscopic plateaus, facets, of a periodic surface corrugation in 1+1…

Statistical Mechanics · Physics 2017-10-24 Jian-Guo Liu , Jianfeng Lu , Dionisios Margetis , Jeremy L. Marzuola

The amplification of an external signal is a key step in direction sensing of biological cells. We consider a simple model for the response to a time-depending signal, which was previously proposed by the last three authors. The model…

Analysis of PDEs · Mathematics 2020-06-30 Anna Logioti , Barbara Niethammer , Matthias Röger , Juan J. L. Velázquez

An analytical study on crease formations in a swelling gel layer is conducted. By exploring the smallness of the layer thickness and using a method of coupled series-asymptotic expansions, the original nonlinear eigenvalue problem of…

Soft Condensed Matter · Physics 2014-10-31 Xiaoyi Chen , Hui-Hui Dai

We are concerned with the global bifurcation analysis of positive solutions to free boundary problems arising in plasma physics. We show that in general, in the sense of domain variations, the following alternative holds: either the shape…

Analysis of PDEs · Mathematics 2021-12-13 Daniele Bartolucci , Yeyao Hu , Aleks Jevnikar , Wen Yang

We describe how some differential geometric bifurcation problems can be treated with the MATLAB continuation and bifurcation toolbox pde2path. The basic setup consists in solving the PDEs for the normal displacement of an immersed surface…

Differential Geometry · Mathematics 2023-09-08 Alexander Meiners , Hannes Uecker

Motivated by recent studies of bifurcations in liquid crystals cells [1,2] we consider a nonlinear pendulum ordinary differential equation in the bounded interval $(-L, L)$ with non-homogeneous mixed boundary conditions (Dirichlet an one…

Dynamical Systems · Mathematics 2019-07-31 Fernando P. da Costa , Michael Grinfeld , João T. Pinto , Kedtysack Xayxanadasy

In [5] the structure of the bifurcation diagrams of a class of superlinear indefinite problems with a symmetric weight was ascertained, showing that they consist of a primary branch and secondary loops bifurcating from it. In [4] it has…

Classical Analysis and ODEs · Mathematics 2015-12-08 Andrea Tellini

Hematopoiesis is a complex biological process that leads to the production and regulation of blood cells. It is based upon differentiation of stem cells under the action of growth factors. A mathematical approach of this process is proposed…

Classical Analysis and ODEs · Mathematics 2009-04-17 Mostafa Adimy , Fabien Crauste , Shigui Ruan

The motor neuron disease amyotrophic lateral sclerosis (ALS) typically begins with localized muscle weakness. Progressive, widespread paralysis often follows over a few years. Does the disease begin with local changes in a small piece of…

Populations and Evolution · Quantitative Biology 2016-10-20 Steven A. Frank

Aeroelastic flutter represents a critical nonlinear instability arising from the coupling between structural elasticity and unsteady aerodynamics. In deterministic settings, flutter onset is associated with bifurcations of invariant sets…

Fluid Dynamics · Physics 2026-05-20 Sunia Tanweer , Firas A. Khasawneh

Local bifurcation theory typically deals with the response of a degenerate but isolated equilibrium state or periodic orbit of a dynamical system to perturbations controlled by one or more independent parameters, and characteristically uses…

Dynamical Systems · Mathematics 2010-02-23 D. R. J. Chillingworth , L. Sbano

We investigate the nonlinear Schr\"odinger equation on a three-edge star graph, where each edge contains a linear localized inhomogeneity in the form of a Dirac delta linear potential. Such systems are of significant interest in studying…

Pattern Formation and Solitons · Physics 2025-09-03 Rahmi Rusin , Hadi Susanto

We provide a rather simple proof of a homogenization result for the bidomain model of cardiac electrophysiology. Departing from a microscopic cellular model, we apply the theory of two-scale convergence to derive the bidomain model. To…

Analysis of PDEs · Mathematics 2018-11-20 Erik Grandelius , Kenneth H. Karlsen

We propose a model for cell polarization as a response to an external signal which results in a system of PDEs for different variants of a protein on the cell surface and interior respectively. We study stationary states of this model in…

Analysis of PDEs · Mathematics 2019-02-18 Barbara Niethammer , Matthias Röger , Juan J. L. Velázquez

The experimental actualisation of organoids modelling organs from brains to pancreases has revealed that much of the diverse morphologies of organs are emergent properties of simple intercellular "rules" and not the result of top-down…

Tissues and Organs · Quantitative Biology 2019-10-07 Julius B. Kirkegaard , Bjarke F. Nielsen , Ala Trusina , Kim Sneppen
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