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Tomography is the three-dimensional reconstruction of an object from images taken at different angles. The term classical tomography is used, when the imaging beam travels in straight lines through the object. This assumption is valid for…

Quantitative Methods · Quantitative Biology 2016-10-10 Paul Müller , Mirjam Schürmann , Jochen Guck

Three-dimensional phase contrast imaging of multiply-scattering samples in X-ray and electron microscopy is extremely challenging, due to small numerical apertures, the unavailability of wavefront shaping optics, and the highly nonlinear…

Computational Physics · Physics 2021-06-02 Philipp M Pelz , Hamish G Brown , Jim Ciston , Scott D Findlay , Yaqian Zhang , Mary Scott , Colin Ophus

Recently introduced speckle-correlations based techniques enable noninvasive imaging of objects hidden behind scattering layers. In these techniques the hidden object Fourier amplitude is retrieved from the scattered light autocorrelation,…

Optics · Physics 2022-01-19 Tengfei Wu , Ori Katz , Xiaopeng Shao , Sylvain Gigan

Imaging with optical resolution through highly scattering media is a long sought-after goal with important applications in deep tissue imaging. Although being the focus of numerous works, this goal was considered impractical until recently.…

Optics · Physics 2012-02-10 Ori Katz , Eran Small , Yaron Silberberg

In optical diffraction tomography (ODT), a sample's 3D refractive-index (RI) is often reconstructed after illuminating it from multiple angles, with the assumption that the sample remains static throughout data collection. When the sample…

Optics · Physics 2024-12-13 Jeongsoo Kim , Shwetadwip Chowdhury

Fluorescence imaging is an essential diagnostic tool in many fields, but diffraction-limited optical imaging at depth is limited by scattering. Here, we present a method based on multiple random illuminations, combined with a computational…

Optics · Physics 2026-03-30 Lei Zhu , Tengfei Wu , Bernhard Rauer , Hilton B. de Aguiar , Sylvain Gigan

Optical coherence tomography (OCT) is a non-invasive, micrometer-scale imaging modality that has become a clinical standard in ophthalmology. By raster-scanning the retina, sequential cross-sectional image slices are acquired to generate…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Stefan Ploner , Jungeun Won , Julia Schottenhamml , Jessica Girgis , Kenneth Lam , Nadia Waheed , James Fujimoto , Andreas Maier

While the implementation of single particle coherent diffraction imaging for non-crystalline particles is complicated by current limitations in photon flux, hit rate, and sample delivery a concept of many-particle coherent diffraction…

Disordered Systems and Neural Networks · Physics 2013-02-22 R. P. Kurta , R. Dronyak , M. Altarelli , E. Weckert , I. A. Vartanyants

Phase-sensitive coherent imaging exploits changes in the phases of backscattered light to observe tiny alterations of scattering structures or variations of the refractive index. But moving scatterers or a fluctuating refractive index…

Three-dimensional (3D) high-resolution imaging is essential in microscopy, yet light scattering poses significant challenges in achieving it. Here, we present an approach to holographic imaging of spatially incoherent objects through…

Optics · Physics 2025-02-04 YoonSeok Baek , Hilton B. de Aguiar , Sylvain Gigan

Coherent diffractive imaging is a technique that recovers the sample image by numerically inverting its diffraction pattern. We propose a generalization of this method for the inversion of multi-wavelength data. Using this approach, we show…

Optics · Physics 2020-05-08 Erik Malm , Edwin Fohtung , Anders Mikkelsen

The Fourier inversion of phased coherent diffraction patterns offers images without the resolution and depth-of-focus limitations of lens-based tomographic systems. We report on our recent experimental images inverted using recent…

There is widespread interest in estimating the fluorescence properties of natural materials in an image. However, the separation between reflected and fluoresced components is difficult, because it is impossible to distinguish reflected and…

Computer Vision and Pattern Recognition · Computer Science 2016-05-16 Henryk Blasinski , Joyce Farrell , Brian Wandell

The ability to measure polarisation, spectrum, temporal dynamics, and spatial amplitude and phase of optical beams is essential to study fundamental phenomena in laser dynamics, telecommunications and nonlinear optics. Current…

A solution to the inversion problem of scattering would offer aberration-free diffraction-limited 3D images without the resolution and depth-of-field limitations of lens-based tomographic systems. Powerful algorithms are increasingly being…

Many naturally-occuring models in the sciences are well-approximated by simplified models, using multiscale techniques. In such settings it is natural to ask about the relationship between inverse problems defined by the original problem…

Numerical Analysis · Mathematics 2019-02-28 Kit Newton , Qin Li , Andrew Stuart

In absence of a lens to form an image, incoherent or partially coherent light scattering off an obstructive or reflective object forms a broad intensity distribution in the far field with only feeble spatial features. We show here that…

We proposed a novel approach to coherent imaging of dynamic samples. The inter-frame similarity of the sample's local structures is found to be a powerful constraint in phasing a sequence of diffraction patterns. We devised a new image…

Optics · Physics 2024-07-11 Pengju Sheng , Fucai Zhang

Many important microscopy samples, such as liquid crystals, biological tissue, or starches, are birefringent in nature. They scatter light differently depending on the light polarization and molecular orientations. The complete…

Optics · Physics 2022-12-26 Herve Hugonnet , Moosung Lee , Seungwoo Shin , YongKeun Park

Optical interferometers provide multiple wavelength measurements. In order to fully exploit the spectral and spatial resolution of these instruments, new algorithms for image reconstruction have to be developed. Early attempts to deal with…

Instrumentation and Methods for Astrophysics · Physics 2015-06-11 Éric Thiébaut , Ferréol Soulez , Loïc Denis