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Related papers: Impact-Induced Cartilage Damage Assessed using Pol…

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Recent studies have shown potential for using polarisation sensitive optical coherence tomography (PS-OCT) to study cartilage morphology, and to be potentially used as an in-vivo, non-invasive tool for detecting osteoarthritic changes.…

Conventional methods for analysing cartilage microstructure under mechanical loading are largely destructive. In this work, we evaluate the efficacy of using depth-resolved polarisation sensitive optical coherence tomography (PS-OCT) to…

Objective: To explore the ability of polarisation-sensitive optical coherence tomography (PS-OCT) to rapidly identify subtle signs of tissue degeneration in the equine joint. Design: Polarisation-sensitive optical coherence tomography…

Mounting evidence for the role of oxidative stress in the degeneration of articular cartilage after an injurious impact requires our modeling & simulation efforts to temporarily shift from just describing the effect of mechanical stress and…

Cell Behavior · Quantitative Biology 2023-02-14 Georgi I. Kapitanov , Bruce P. Ayati , James A. Martin

The degeneration of articular cartilage (AC) occurs in osteoarthritis (OA), which is a leading cause of pain and disability in middle-aged and older people. The early disease related changes in cartilage extra-cellular matrix (ECM) start…

In previous works, the author and collaborators establish a mathematical model for injury response in articular cartilage. In this paper we use mathematical software and computational techniques, applied to an existing model to explore in…

Quantitative Methods · Quantitative Biology 2013-07-26 Jason M Graham

Mechanical stress-induced damage to the articular cartilage can result in fracture imitation or significant tissue degeneration leading to osteoarthritis (OA) compromising joint mobility. Despite the clinical significance, a comprehensive…

Medical Physics · Physics 2024-11-26 Dipul Chawla , Eric Kazyak , Melih Eriten , Corinne R. Henak

Articular cartilage showcases distinctive mechanical behaviour, attributable to its biphasic composition and hierarchical organization. Proteoglycans, essential constituents of the extracellular matrix, contribute to tissue swelling,…

Medical Physics · Physics 2025-10-24 S. Fantoni , M. Berni , R. Fognani , G. Fraterrigo , P. Cardarelli , F. Baruffaldi , M. Baleani

In this paper, the objective is to assess the histomechanical effects of collagen proteolysis in arteries under loading conditions reproducing in vivo environment. Thirteen segments of common porcine carotid arteries (8 proximal and 5…

Medical Physics · Physics 2019-12-13 Olfa Trabelsi , Virginie Dumas , Edouard Breysse , Norbert Laroche , StéPhane Avril

We demonstrate that polarization-sensitive optical coherence tomography (PS-OCT) is suitable to map the stress distribution within materials in a contactless and non-destructive way. In contrast to transmission photoelasticity measurements…

Evaluating impact-induced damage in composite materials under varying temperature conditions is essential for ensuring structural integrity and reliable performance in aerospace, polar, and other extreme-environment applications. As matrix…

In recent years, dynamic indentation tests have been shown to be useful both in identification of mechanical properties of biological tissues (such as articular cartilage) and assessing their viability. We consider frictionless flat-ended…

Biological Physics · Physics 2015-06-04 I. Argatov , A. U. Daniels , G. Mishuris , S. Ronken , D. Wirz

Intravascular polarimetry with catheter-based polarization-sensitive optical coherence tomography (PS-OCT) complements the high-resolution structural tomograms of OCT with morphological contrast available through polarimetry. Its clinical…

We present a model of articular cartilage lesion formation to simulate the effects of cyclic loading. This model extends and modifies the reaction-diffusion-delay model by Graham et al. 2012 for the spread of a lesion formed though a single…

Tissues and Organs · Quantitative Biology 2023-02-14 Xiayi Wang , Bruce P. Ayati , Marc J. Brouillete , Jason M. Graham , Prem S. Ramakrishnan , James A. Martin

In the present paper, an asymptotic model is constructed for the short-time deformation of an articular cartilage layer modeled as transversely isotropic, transversely homogeneous (TITH) biphasic material. It is assumed that the layer…

Tissues and Organs · Quantitative Biology 2015-12-01 Gennaro Vitucci , Ivan Argatov , Gennady Mishuris

The optical damage of photorefractive material, single LiNbO3 crystal, is experimentally studied. The specimen has been illuminated with the radiation of continuous Ar-laser (the wavelength of 488 nm) focused to 35?m spot. The induced…

General Physics · Physics 2007-08-16 O. Krupych , I. Smaga , R. Vlokh

The analysis of negative birefringence optically induced in major air components (Loriot et al., [1, 2]) is revisited in light of the recently reported plasma grating-induced phase-shift effect predicted for strong field pump-probe…

Optics · Physics 2015-06-17 G. Karras , P. Béjot , J. Houzet , E. Hertz , F. Billard , B. Lavorel , O. Faucher

Cartilage degeneration in joints causing pain and various types of knee problems is a serious problem-affecting people in all ages. Degenerated articular cartilage is also known as a central hallmark of osteoarthritis, which is a complex…

Applied Physics · Physics 2019-12-16 Abhishek Ranjan , Chengxiang peng , Anowarul Habib , Sanat Wagle , Frank Melandso

Healthy articular cartilage, covering the ends of bones in major joints such as hips and knees, presents the most efficiently-lubricated surface known in nature, with friction coefficients as low as 0.001 up to physiologically high…

Medical Physics · Physics 2023-11-07 Weifeng Lin , Jacob Klein

Inhomogeneity and anisotropy play a crucial role in attributing articular cartilage its properties. The frictionless contact model constructed here consists in two thin biphasic transversely isotropic transversely homogeneous (TITH)…

Tissues and Organs · Quantitative Biology 2016-10-18 Gennaro Vitucci , Gennady Mishuris
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