Depth-resolved polarisation sensitive optical coherence tomography reveals the complex microanatomical response of cartilage to compression
Optics
2025-07-30 v1 Medical Physics
Abstract
Conventional methods for analysing cartilage microstructure under mechanical loading are largely destructive. In this work, we evaluate the efficacy of using depth-resolved polarisation sensitive optical coherence tomography (PS-OCT) to study the cartilage morphological response to compression. We show that depth-resolved PS-OCT reveals the microstructure of cartilage under load, and it can do so non-destructively, opening significant possibilities for enhanced clinical assessment of cartilage health by detecting deviance from normal load-bearing behaviour.
Keywords
Cite
@article{arxiv.2507.21427,
title = {Depth-resolved polarisation sensitive optical coherence tomography reveals the complex microanatomical response of cartilage to compression},
author = {Darven Murali Tharan and Marco Bonesi and Daniel Everett and Matthew Goodwin and Cushla McGoverin and Sue McGlashan and Ashvin Thambyah and Frédérique Vanholsbeeck},
journal= {arXiv preprint arXiv:2507.21427},
year = {2025}
}
Comments
23 pages, 11 figures