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Network scientists have proposed that infectious diseases involving person-to-person transmission may be effectively halted by targeting interventions at a minority of highly connected individuals. Can this strategy be effective in…

Social and Information Networks · Computer Science 2020-11-16 Gianluca Manzo , Arnout van de Rijt

The determination of the infection fatality rate (IFR) for the novel SARS-CoV-2 coronavirus is a key aim for many of the field studies that are currently being undertaken in response to the pandemic. The IFR together with the basic…

We present several related methods for creating confidence intervals to assess disease prevalence in variety of survey sampling settings. These include simple random samples with imperfect tests, weighted sampling with perfect tests, and…

Methodology · Statistics 2023-03-14 Damon Bayer , Michael Fay , Barry Graubard

Solid estimates describing the clinical course of SARS-CoV-2 infections are still lacking due to under-ascertainment of asymptomatic and mild-disease cases. In this work, we quantify age-specific probabilities of transitions between stages…

Understanding the spread of SARS-CoV-2 has been one of the most pressing problems of the recent past. Network models present a potent approach to studying such spreading phenomena because of their ability to represent complex social…

Social and Information Networks · Computer Science 2023-11-01 Christine Hedde-von Westernhagen , Javier Garcia-Bernardo , Ayoub Bagheri

Superspreading complicates the study of SARS-CoV-2 transmission. I propose a model for aggregated case data that accounts for superspreading and improves statistical inference. In a Bayesian framework, the model is estimated on German data…

Applications · Statistics 2020-11-10 Patrick W. Schmidt

Understanding the number of individuals who have been infected with the novel coronavirus SARS-CoV-2, and the extent to which social distancing policies have been effective at limiting its spread, are critical for effective policy going…

Applications · Statistics 2020-04-21 James Johndrow , Kristian Lum , Maria Gargiulo , Patrick Ball

In India the COVID-19 infected population has not yet been accurately established. As always in the early stages of any epidemic, the need to test serious cases first has meant that the population with asymptomatic or mild sub-clinical…

Populations and Evolution · Quantitative Biology 2020-04-09 Sourendu Gupta , R. Shankar

Repeat asymptomatic testing in order to identify and quarantine infectious individuals has become a widely-used intervention to control SARS-CoV-2 transmission. In some workplaces, and in particular health and social care settings with…

Populations and Evolution · Quantitative Biology 2022-10-18 Carl A Whitfield , University of Manchester COVID-19 Modelling Group , Ian Hall

Large scale virological testing of SARS-Cov2 is implemented since May 2020 in France. We assume that the positivity of asymptomatic people not being contact cases (ANBC) is representative of the positivity of the whole French population,…

Populations and Evolution · Quantitative Biology 2020-11-03 Guillaume Malpuech , Anne Tournadre , Francois Berry , Laurent Gerbaud

There are many hard-to-reconcile numbers circulating concerning Covid-19. Using reports from random testing, the fatality ratio per infection is evaluated and used to extract further information on the actual fraction of infections and the…

Populations and Evolution · Quantitative Biology 2020-05-25 Allen Caldwell , Vasyl Hafych , Oliver SChulz , Lolian Shtembari

Since December 2019 the novel coronavirus SARS-CoV-2 has been identified as the cause of the pandemic COVID-19. Early symptoms overlap with other common conditions such as common cold and Influenza, making early screening and diagnosis are…

Coronavirus case-count data has influenced government policies and drives most epidemiological forecasts. Limited testing is cited as the key driver behind minimal information on the COVID-19 pandemic. While expanded testing is laudable,…

Methodology · Statistics 2022-09-22 Walter Dempsey

Public health policy makers are faced with making crucial decisions rapidly during infectious disease outbreaks such as that caused by SARS-CoV-2. Ideally, rapidly deployed representative health surveys could provide needed data for such…

Applications · Statistics 2023-06-16 Yan Li , Laura Yee , Sally Hunsberger , Matthew J. Memoli , Kaitlyn Sadtler , Barry I. Graubard

Through the use of cutting-edge unsupervised classification techniques from statistics and machine learning, we characterise symptom phenotypes among symptomatic SARS-CoV-2 PCR-positive community cases. We first analyse each dataset in…

During 2020 and 2021, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission has been increasing amongst the world's population at an alarming rate. Reducing the spread of SARS-CoV-2 and other diseases that are spread in…

Social and Information Networks · Computer Science 2022-03-22 Patrick Urrutia , David Wren , Chrysafis Vogiatzis , Ruriko Yoshida

It is crucial for policymakers to understand the community prevalence of COVID-19 so combative resources can be effectively allocated and prioritized during the COVID-19 pandemic. Traditionally, community prevalence has been assessed…

The COVID-19 outbreak is asynchronous in US counties. Mitigating the COVID-19 transmission requires not only the state and federal level order of protective measures such as social distancing and testing, but also public awareness of…

Applications · Statistics 2021-05-03 Hanmo Li , Mengyang Gu

We argue that frequent sampling of the fraction of infected people (either by random testing or by analysis of sewage water), is central to managing the COVID-19 pandemic because it both measures in real time the key variable controlled by…

Populations and Evolution · Quantitative Biology 2020-07-24 Markus Müller , Peter M. Derlet , Christopher Mudry , Gabriel Aeppli

We develop a statistical model for the testing of disease prevalence in a population. The model assumes a binary test result, positive or negative, but allows for biases in sample selection and both type I (false positive) and type II…

Applications · Statistics 2021-12-28 Lucas Böttcher , Maria R. D'Orsogna , Tom Chou