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In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Ario Sadafi , Nassir Navab , Carsten Marr

Understanding how the brain's complex nonlinear dynamics give rise to cognitive function remains a central challenge in neuroscience. While brain functional dynamics exhibits scale-free and multifractal properties across temporal scales,…

Neurons and Cognition · Quantitative Biology 2025-06-18 Sangyoon Bae , Junbeom Kwon , Shinjae Yoo , Jiook Cha

Machine learning (ML) techniques have gained popularity in the neuroimaging field due to their potential for classifying neuropsychiatric disorders. However, the diagnostic predictive power of the existing algorithms has been limited by…

Medical vision-language pretraining (VLP) models have recently been investigated for their generalization to diverse downstream tasks. However, current medical VLP methods typically force the model to learn simple and complex concepts…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Chenran Zhang , Ruiqi Wu , Tao Zhou , Yi Zhou

Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional…

Neurons and Cognition · Quantitative Biology 2025-02-25 Bishal Thapaliya , Robyn Miller , Jiayu Chen , Yu-Ping Wang , Esra Akbas , Ram Sapkota , Bhaskar Ray , Pranav Suresh , Santosh Ghimire , Vince Calhoun , Jingyu Liu

For medical imaging AI models to be clinically impactful, they must generalize. However, this goal is hindered by (i) diverse types of distribution shifts, such as temporal, demographic, and label shifts, and (ii) limited diversity in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Kumail Alhamoud , Yasir Ghunaim , Motasem Alfarra , Thomas Hartvigsen , Philip Torr , Bernard Ghanem , Adel Bibi , Marzyeh Ghassemi

A multi-modal machine learning system uses multiple unique data sources and types to improve its performance. This article proposes a system that combines results from several types of models, all of which are trained on different data…

Machine Learning · Computer Science 2024-02-05 Aaron Mullen , Samuel E. Armstrong , Jasmine Perdeh , Bjorn Bauer , Jeffrey Talbert , V. K. Cody Bumgardner

Multi-instance learning (MIL) is a widely-applied technique in practical applications that involve complex data structures. MIL can be broadly categorized into two types: traditional methods and those based on deep learning. These…

Artificial Intelligence · Computer Science 2023-04-25 Yu-Xuan Zhang , Zhengchun Zhou , Xingxing He , Avik Ranjan Adhikary , Bapi Dutta

In symbolic regression, the search for analytic models is typically driven purely by the prediction error observed on the training data samples. However, when the data samples do not sufficiently cover the input space, the prediction error…

Machine Learning · Computer Science 2020-04-28 J. Kubalík , E. Derner , R. Babuška

Education is a dynamic field that must be adaptable to sudden changes and disruptions caused by events like pandemics, war, and natural disasters related to climate change. When these events occur, traditional classrooms with traditional or…

Computers and Society · Computer Science 2024-02-23 Hani Y. Ayyoub , Omar S. Al-Kadi

Multiple Instance Learning (MIL) is widely used in medical imaging classification to reduce the labeling effort. While only bag labels are available for training, one typically seeks predictions at both bag and instance levels…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Francisco M. Castro-Macías , Pablo Morales-Álvarez , Yunan Wu , Rafael Molina , Aggelos K. Katsaggelos

Diagnosing Autism Spectrum Disorder (ASD) is a challenging problem, and is based purely on behavioral descriptions of symptomology (DSM-5/ICD-10), and requires informants to observe children with disorder across different settings (e.g.…

Neurons and Cognition · Quantitative Biology 2020-03-04 Taban Eslami , Joseph S. Raiker , Fahad Saeed

This paper presents a novel holistic deep learning framework that simultaneously addresses the challenges of vulnerability to input perturbations, overparametrization, and performance instability from different train-validation splits. The…

In recent years, the integration of pre-trained foundational models with multiple instance learning (MIL) has improved diagnostic accuracy in computational pathology. However, existing MIL methods focus on optimizing feature extractors and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-24 Le Feng , Li Xiao

Representation learning has been evolving from traditional supervised training to Contrastive Learning (CL) and Masked Image Modeling (MIM). Previous works have demonstrated their pros and cons in specific scenarios, i.e., CL and supervised…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Bowen Shi , Xiaopeng Zhang , Yaoming Wang , Jin Li , Wenrui Dai , Junni Zou , Hongkai Xiong , Qi Tian

We propose Spatial-Aware Correlated Multiple Instance Learning (SAC-MIL) for performing WSI classification. SAC-MIL consists of a positional encoding module to encode position information and a SAC block to perform full instance…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Yu Bai , Zitong Yu , Haowen Tian , Xijing Wang , Shuo Yan , Lin Wang , Honglin Li , Xitong Ling , Bo Zhang , Zheng Zhang , Wufan Wang , Hui Gao , Xiangyang Gong , Wendong Wang

Diabetes mellitus affects over 537 million adults worldwide and remains a major challenge in preventive healthcare. Existing machine-learning studies primarily formulate diabetes prediction as a binary classification problem, while…

Machine Learning · Computer Science 2026-05-14 Vishal Pandey , Ruzina Haque Laskar , Rishav Tewari

Resting-state fMRI is commonly used for diagnosing Autism Spectrum Disorder (ASD) by using network-based functional connectivity. It has been shown that ASD is associated with brain regions and their inter-connections. However,…

Neurons and Cognition · Quantitative Biology 2022-01-04 Ranjeet Ranjan Jha , Abhishek Bhardwaj , Devin Garg , Arnav Bhavsar , Aditya Nigam

We present SAM, a biologically-plausible selective attention-driven modulation approach to enhance classification models in a continual learning setting. Inspired by neurophysiological evidence that the primary visual cortex does not…

Computer Vision and Pattern Recognition · Computer Science 2024-04-01 Giovanni Bellitto , Federica Proietto Salanitri , Matteo Pennisi , Matteo Boschini , Angelo Porrello , Simone Calderara , Simone Palazzo , Concetto Spampinato

In the realm of digital pathology, multi-magnification Multiple Instance Learning (multi-mag MIL) has proven effective in leveraging the hierarchical structure of Whole Slide Images (WSIs) to reduce information loss and redundant data.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-11 Yujian Liu , Ruoxuan Wu , Xinjie Shen , Zihuang Lu , Lingyu Liang , Haiyu Zhou , Shipu Xu , Shaoai Cai , Shidang Xu