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This paper introduces a new method to solve the cross-domain recognition problem. Different from the traditional domain adaption methods which rely on a global domain shift for all classes between source and target domain, the proposed…
Despite deep convolutional neural networks achieved impressive progress in medical image computing and analysis, its paradigm of supervised learning demands a large number of annotations for training to avoid overfitting and achieving…
Deep learning (DL) has made significant progress in angle closure classification with anterior segment optical coherence tomography (AS-OCT) images. These AS-OCT images are often acquired by different imaging devices/conditions, which…
The past decade's "cryoEM revolution" has produced exponential growth in high-resolution structural data through advances in cryogenic electron microscopy (cryoEM) and tomography (cryoET). Deep learning integration into structural…
The detection of nuclei is one of the most fundamental components of computational pathology. Current state-of-the-art methods are based on deep learning, with the prerequisite that extensive labeled datasets are available. The increasing…
Self-supervised learning has demonstrated considerable potential in hyperspectral representation, yet its application in cross-domain transfer scenarios remains under-explored. Existing methods, however, still rely on source domain…
Cryo-electron microscopy (cryo-EM) has revolutionized experimental protein structure determination. Despite advances in high resolution reconstruction, a majority of cryo-EM experiments provide either a single state of the studied…
While many deep learning methods have seen significant success in tackling the problem of domain adaptation and few-shot learning separately, far fewer methods are able to jointly tackle both problems in Cross-Domain Few-Shot Learning…
Current machine learning has made great progress on computer vision and many other fields attributed to the large amount of high-quality training samples, while it does not work very well on genomic data analysis, since they are notoriously…
Few-shot domain adaptation to multiple domains aims to learn a complex image distribution across multiple domains from a few training images. A na\"ive solution here is to train a separate model for each domain using few-shot domain…
This study presents an unsupervised domain adaptation method aimed at autonomously generating image masks outlining regions of interest (ROIs) for differentiating breast lesions in breast ultrasound (US) imaging. Our semi-supervised…
Due to the emergence of powerful computing resources and large-scale annotated datasets, deep learning has seen wide applications in our daily life. However, most current methods require extensive data collection and retraining when dealing…
Cryo-electron tomography (cryoET) is a crucial technique for unveiling the structure of protein complexes. Automatically analyzing tomograms captured by cryoET is an essential step toward understanding cellular structures. In this paper, we…
Cryo-electron microscopy (cryo-EM) has revolutionized structural biology by enabling near-atomic-level visualization of biomolecular assemblies. However, the exponential growth in cryo-EM data throughput and complexity, coupled with diverse…
Most few-shot learning techniques are pre-trained on a large, labeled "base dataset". In problem domains where such large labeled datasets are not available for pre-training (e.g., X-ray, satellite images), one must resort to pre-training…
We provide in this paper a comprehensive comparison of various transfer learning strategies and deep learning architectures for computer-aided classification of adult-type diffuse gliomas. We evaluate the generalizability of out-of-domain…
Fine-tuning a deep network trained with the standard cross-entropy loss is a strong baseline for few-shot learning. When fine-tuned transductively, this outperforms the current state-of-the-art on standard datasets such as Mini-ImageNet,…
Segmenting images is critical for visual understanding but demands extensive pixel-level annotations. Foundational models have enabled new paradigms for predicting new classes guided by textual prompts, without annotations from the target…
Deep neural networks (DNNs) have been widely used for medical image analysis. However, the lack of access a to large-scale annotated dataset poses a great challenge, especially in the case of rare diseases, or new domains for the research…
High-throughput screening using automated microscopes is a key driver in biopharma drug discovery, enabling the parallel evaluation of thousands of drug candidates for diseases such as cancer. Traditional image analysis and deep learning…