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We develop an empirical Bayes procedure for estimating the cell means in an unbalanced, two-way additive model with fixed effects. We employ a hierarchical model, which reflects exchangeability of the effects within treatment and within…

Methodology · Statistics 2016-05-30 Lawrence D. Brown , Gourab Mukherjee , Asaf Weinstein

We present a new Bayesian methodology to learn the unknown material density of a given sample by inverting its two-dimensional images that are taken with a Scanning Electron Microscope. An image results from a sequence of projections of the…

Applications · Statistics 2014-03-06 Dalia Chakrabarty , Fabio Rigat , Nare Gabrielyan , Richard Beanland , Shashi Paul

Unsupervised learning with functional data is an emerging paradigm of machine learning research with applications to computer vision, climate modeling and physical systems. A natural way of modeling functional data is by learning operators…

Machine Learning · Computer Science 2023-02-22 Jacob H. Seidman , Georgios Kissas , George J. Pappas , Paris Perdikaris

A new empirical Bayes approach to variable selection in the context of generalized linear models is developed. The proposed algorithm scales to situations in which the number of putative explanatory variables is very large, possibly much…

Methodology · Statistics 2021-06-29 Haim Bar , James Booth , Martin T. Wells

Bayesian optimisation (BO) has been a successful approach to optimise functions which are expensive to evaluate and whose observations are noisy. Classical BO algorithms, however, do not account for errors about the location where…

Machine Learning · Computer Science 2019-02-22 Rafael Oliveira , Lionel Ott , Fabio Ramos

Normalization techniques are important in different advanced neural networks and different tasks. This work investigates a novel dynamic learning-to-normalize (L2N) problem by proposing Exemplar Normalization (EN), which is able to learn…

Computer Vision and Pattern Recognition · Computer Science 2020-03-23 Ruimao Zhang , Zhanglin Peng , Lingyun Wu , Zhen Li , Ping Luo

Deep latent variable models have achieved significant empirical successes in model-based reinforcement learning (RL) due to their expressiveness in modeling complex transition dynamics. On the other hand, it remains unclear theoretically…

Machine Learning · Computer Science 2023-03-08 Tongzheng Ren , Chenjun Xiao , Tianjun Zhang , Na Li , Zhaoran Wang , Sujay Sanghavi , Dale Schuurmans , Bo Dai

Variational Autoencoders (VAEs) have been shown to be remarkably effective in recovering model latent spaces for several computer vision tasks. However, currently trained VAEs, for a number of reasons, seem to fall short in learning…

Machine Learning · Computer Science 2021-07-27 Chandrajit Bajaj , Avik Roy , Haoran Zhang

Bayesian entity resolution merges together multiple, noisy databases and returns the minimal collection of unique individuals represented, together with their true, latent record values. Bayesian methods allow flexible generative models…

Methodology · Statistics 2014-10-20 Tamara Broderick , Rebecca C. Steorts

Recent progress in deep latent variable models has largely been driven by the development of flexible and scalable variational inference methods. Variational training of this type involves maximizing a lower bound on the log-likelihood,…

Machine Learning · Computer Science 2016-06-02 Andriy Mnih , Danilo J. Rezende

Inference in discrete graphical models with variational methods is difficult because of the inability to re-parameterize gradients of the Evidence Lower Bound (ELBO). Many sampling-based methods have been proposed for estimating these…

Machine Learning · Computer Science 2020-10-23 Andy Shih , Stefano Ermon

In variational inference (VI), the marginal log-likelihood is estimated using the standard evidence lower bound (ELBO), or improved versions as the importance weighted ELBO (IWELBO). We propose the multiple importance sampling ELBO…

Machine Learning · Computer Science 2022-02-23 Oskar Kviman , Harald Melin , Hazal Koptagel , Víctor Elvira , Jens Lagergren

Standard practice obtains an unbiased variance estimator by dividing by $N-1$ rather than $N$. Yet if only half the data are used to compute the mean, dividing by $N$ can still yield an unbiased estimator. We show that an alternative mean…

Statistics Theory · Mathematics 2025-04-10 Dai Akita

An index of an effective number of variables (ENV) is introduced for model selection in nested models. This is the case, for instance, when we have to decide the order of a polynomial function or the number of bases in a nonlinear…

Methodology · Statistics 2026-02-26 Luca Martino , Eduardo Morgado , Roberto San Millán-Castillo

Non-linear hierarchical models are commonly used in many disciplines. However, inference in the presence of non-nested effects and on large datasets is challenging and computationally burdensome. This paper provides two contributions to…

Methodology · Statistics 2021-10-22 Max Goplerud

Inference in both brains and machines can be formalized by optimizing a shared objective: maximizing the evidence lower bound (ELBO) in machine learning, or minimizing variational free energy (F) in neuroscience (ELBO = -F). While this…

Artificial Intelligence · Computer Science 2025-10-27 Hadi Vafaii , Dekel Galor , Jacob L. Yates

Bayesian neural networks (BNN) promise to combine the predictive performance of neural networks with principled uncertainty modeling important for safety-critical systems and decision making. However, posterior uncertainty estimates depend…

Machine Learning · Computer Science 2025-06-06 Tristan Cinquin , Robert Bamler

While energy-based models (EBMs) exhibit a number of desirable properties, training and sampling on high-dimensional datasets remains challenging. Inspired by recent progress on diffusion probabilistic models, we present a diffusion…

Machine Learning · Computer Science 2021-03-30 Ruiqi Gao , Yang Song , Ben Poole , Ying Nian Wu , Diederik P. Kingma

Given a collection of observed signals corrupted with Gaussian noise, how can we learn to optimally denoise them? This fundamental problem arises in both empirical Bayes and generative modeling. In empirical Bayes, the predominant approach…

Statistics Theory · Mathematics 2025-09-25 Sulagna Ghosh , Nikolaos Ignatiadis , Frederic Koehler , Amber Lee

Discrete diffusion models are often trained through clean-data prediction, but the prediction can be used in different ways to define the reverse dynamics. In Masked Diffusion Models (MDM) these choices largely coincide, whereas in Uniform…

Machine Learning · Computer Science 2026-05-22 Samson Gourevitch , Yazid Janati , Dario Shariatian , Umut Simsekli , Eric Moulines , Eric P. Xing , Alain Durmus