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We summarize recent progress on the theory and applications of structural identifiability of compartmental models. On the applications side, we review identifiability analyses undertaken recently for models arising in epidemiology,…

Methodology · Statistics 2025-07-08 Nicolette Meshkat , Anne Shiu

If model identifiability is not confirmed, inferences from infectious disease transmission models may not be reliable, so they might lead to misleading recommendations. Structural identifiability analysis characterizes whether it is…

Quantitative Methods · Quantitative Biology 2022-06-09 Emmanuelle A. Dankwa , Andrew F. Brouwer , Christl A. Donnelly

We consider a model identification problem in which an outcome variable contains nonignorable missing values. Statistical inference requires a guarantee of the model identifiability to obtain estimators enjoying theoretically reasonable…

Methodology · Statistics 2023-07-06 Kenji Beppu , Kosuke Morikawa

A causal input-output system may be described by a function space for inputs, a function space for outputs, and a causal operator mapping the input space into the output space. A particular representation of the state of such a system at…

Dynamical Systems · Mathematics 2010-09-28 Demetrios Serakos

Literature on Constraint Satisfaction exhibits the definition of several structural properties that can be possessed by CSPs, like (in)consistency, substitutability or interchangeability. Current tools for constraint solving typically…

Artificial Intelligence · Computer Science 2014-01-16 Lucas Bordeaux , Marco Cadoli , Toni Mancini

A special aspect of parameter identification in finite-strain elasto-plasticity is considered. Namely, we analyze the impact of the measurement errors on the resulting set of material parameters. In order to define the sensitivity of…

Applications · Statistics 2021-03-15 A. V. Shutov , A. A. Kaygorodtseva

A mathematical model is identifiable if its parameters can be recovered from data. Here, we focus on a particular class of model, linear compartmental models, which are used to represent the transfer of substances in a system. We analyze…

Dynamical Systems · Mathematics 2021-06-22 Patrick Chan , Katherine Johnston , Anne Shiu , Aleksandra Sobieska , Clare Spinner

Linear causal models are important tools for modeling causal dependencies and yet in practice, only a subset of the variables can be observed. In this paper, we examine the parameter identifiability of these models by investigating whether…

Machine Learning · Computer Science 2025-02-11 Xinshuai Dong , Ignavier Ng , Biwei Huang , Yuewen Sun , Songyao Jin , Roberto Legaspi , Peter Spirtes , Kun Zhang

Ordinary differential equations (ODEs) are widely used to model dynamical behavior of systems. It is important to perform identifiability analysis prior to estimating unknown parameters in ODEs (a.k.a. inverse problem), because if a system…

Optimization and Control · Mathematics 2021-03-11 Xing Qiu , Tao Xu , Babak Soltanalizadeh , Hulin Wu

The feasibility of uniquely estimating parameters of dynamical systems from observations is a widely discussed aspect of mathematical modelling. Several approaches have been published for analyzing identifiability. However, they are…

Methodology · Statistics 2017-08-14 Clemens Kreutz

In this work, we consider the problem of robust parameter estimation from observational data in the context of linear structural equation models (LSEMs). LSEMs are a popular and well-studied class of models for inferring causality in the…

Machine Learning · Computer Science 2020-07-15 Karthik Abinav Sankararaman , Anand Louis , Navin Goyal

Within the calibration of material models, often the numerical results of a simulation model $y$ are compared with the experimental measurements $y^*$. Usually, the differences between measurements and simulation are minimized using least…

Materials Science · Physics 2024-08-14 Thomas Most

Latent feature models (LFM)s are widely employed for extracting latent structures of data. While offering high, parameter estimation is difficult with LFMs because of the combinational nature of latent features, and non-identifiability is a…

Machine Learning · Computer Science 2018-09-27 Ryota Suzuki , Shingo Takahashi , Murtuza Petladwala , Shigeru Kohmoto

One version of the concept of structural controllability defined for single-input systems by Lin and subsequently generalized to multi-input systems by others, states that a parameterized matrix pair $(A, B)$ whose nonzero entries are…

Systems and Control · Computer Science 2019-11-12 Fengjiao Liu , A. Stephen Morse

The exact parameter values of mathematical models are often uncertain or even unknown. Nevertheless, we may have access to crude information about the parameters, e.g., that some of them are nonzero. Such information can be captured by…

Optimization and Control · Mathematics 2020-11-25 B. M. Shali , H. J. van Waarde , M. K. Camlibel , H. L. Trentelman

Identifiability means that iterates generated by optimization algorithms are eventually confined to an identifiable set. This property is computationally useful because minimizing a nonsmooth function near a critical point reduces to…

Optimization and Control · Mathematics 2026-05-05 Hanju Wu , Yue Xie

In this paper, we introduce a new identifiability criteria for linear structural equation models, which we call regression identifiability. We provide necessary and sufficient graphical conditions for a directed edge to be regression…

Statistics Theory · Mathematics 2022-05-27 Bohao Yao , Robin J. Evans

The successful application of epidemic models hinges on our ability to estimate model parameters from limited observations reliably. An often-overlooked step before estimating model parameters consists of ensuring that the model parameters…

Quantitative Methods · Quantitative Biology 2023-09-29 Gerardo Chowell , Sushma Dahal , Yuganthi R. Liyanage , Amna Tariq , Necibe Tuncer

State-space models are dynamical systems defined by a latent and an observed process. In ecology, stochastic state-space models in discrete time are most often used to describe the imperfectly observed dynamics of population sizes or animal…

Methodology · Statistics 2025-08-13 Frederic Barraquand , Julien Gibaud

Structural identifiability is the theoretical ability to uniquely recover model parameters from ideal, noise-free data and is a prerequisite for reliable parameter estimation in epidemic modeling. Despite its importance for calibration and…

Quantitative Methods · Quantitative Biology 2026-04-15 Yuganthi R. Liyanage , Omar Saucedo , Necibe Tuncer , Gerardo Chowell
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