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What does it mean to say that a quantity is identifiable from the data? Statisticians seem to agree on a definition in the context of parametric statistical models --- roughly, a parameter $\theta$ in a model $\mathcal{P} = \{P_\theta:…

Methodology · Statistics 2020-02-17 Guillaume Basse , Iavor Bojinov

Scientists use mathematical modelling to understand and predict the properties of complex physical systems. In highly parameterised models there often exist relationships between parameters over which model predictions are identical, or…

Data Analysis, Statistics and Probability · Physics 2017-03-24 Dhruva V. Raman , James Anderson , Antonis Papachristodoulou

Machine learning (ML) and deep learning models are extensively used for parameter optimization and regression problems. However, not all inverse problems in ML are ``identifiable,'' indicating that model parameters may not be uniquely…

Machine Learning · Computer Science 2023-07-24 Reza Sameni

Linear structural equation models, which relate random variables via linear interdependencies and Gaussian noise, are a popular tool for modeling multivariate joint distributions. These models correspond to mixed graphs that include both…

Computation · Statistics 2015-04-14 Mathias Drton , Luca Weihs

In several model-based system maintenance problems, parameters are used to represent unknown characteristics of a component, equipment degradation, etc. This allows for modelling constant, slow-varying terms. The identifiability of these…

Optimization and Control · Mathematics 2020-03-24 Krishnan Srinivasarengan , José Ragot , Christophe Aubrun , Didier Maquin

Differential equation models are crucial to scientific processes. The values of model parameters are important for analyzing the behaviour of solutions. A parameter is called globally identifiable if its value can be uniquely determined…

Quantitative Methods · Quantitative Biology 2024-02-07 Helen Byrne , Heather Harrington , Alexey Ovchinnikov , Gleb Pogudin , Hamid Rahkooy , Pedro Soto

We introduce a class of linear compartmental models called identifiable path/cycle models which have the property that all of the monomial functions of parameters associated to the directed cycles and paths from input compartments to output…

Algebraic Geometry · Mathematics 2021-09-01 Cashous Bortner , Nicolette Meshkat

A Profile Mixture Model is a model of protein evolution, describing sequence data in which sites are assumed to follow many related substitution processes on a single evolutionary tree. The processes depend in part on different amino acid…

Populations and Evolution · Quantitative Biology 2020-07-07 Samaneh Yourdkhani , Elizabeth S. Allman , John A. Rhodes

In a direct data-driven approach, this paper studies the {\em property identification(ID)} problem to analyze whether an unknown linear system has a property of interest, e.g., stabilizability and structural properties. In sharp contrast to…

Systems and Control · Electrical Eng. & Systems 2022-08-30 Shubo Kang , Keyou You

Stochasticity plays a key role in many biological systems, necessitating the calibration of stochastic mathematical models to interpret associated data. For model parameters to be estimated reliably, it is typically the case that they must…

Parameter identifiability refers to the capability of accurately inferring the parameter values of a model from its observations (data). Traditional analysis methods exploit analytical properties of the closed form model, in particular…

Machine Learning · Computer Science 2024-12-30 Nikolaos Evangelou , Alexander M. Stankovic , Ioannis G. Kevrekidis , Mark K. Transtrum

Many models in mathematical epidemiology are developed with the aim to provide a framework for parameter estimation and then prediction. It is well-known that parameters are not always uniquely identifiable. In this paper we consider…

Dynamical Systems · Mathematics 2022-08-17 István Zoltán Kiss , Péter L. Simon

Identifiability of parameters is an essential property for a statistical model to be useful in most settings. However, establishing parameter identifiability for Bayesian networks with hidden variables remains challenging. In the context of…

Statistics Theory · Mathematics 2014-06-04 Elizabeth S. Allman , John A. Rhodes , Elena Stanghellini , Marco Valtorta

Identifiability is a structural property of any ODE model characterized by a set of unknown parameters. It describes the possibility of determining the values of these parameters from fusing the observations of the system inputs and…

Systems and Control · Electrical Eng. & Systems 2024-09-12 Agostino Martinelli

Dynamic models of biochemical networks typically consist of sets of non-linear ordinary differential equations involving states (concentrations or amounts of the components of the network) and parameters describing the reaction kinetics.…

Molecular Networks · Quantitative Biology 2014-03-07 Oana-Teodora Chis , Julio R. Banga , Eva Balsa-Canto

Modelling, parameter identification, and simulation play an important role in systems biology. Usually, the goal is to determine parameter values that minimise the difference between experimental measurement values and model predictions in…

Mathematical Software · Computer Science 2013-04-10 Thomas Dierkes , Susanna Röblitz , Moritz Wade , Peter Deuflhard

This paper deals with the problem of identifying direct causal effects in recursive linear structural equation models. The paper establishes a sufficient criterion for identifying individual causal effects and provides a procedure computing…

Methodology · Statistics 2012-06-26 Jin Tian

The advancement of in-vehicle sensors provides abundant datasets to estimate parameters of car-following models that describe driver behaviors. The question of parameter identifiability of such models (i.e., whether it is possible to infer…

Dynamical Systems · Mathematics 2022-02-21 Yanbing Wang , Maria Laura Delle Monache , Daniel B. Work

We may attempt to encapsulate what we know about a physical system by a model structure, $S$. This collection of related models is defined by parametric relationships between system features; say observables (outputs), unobservable…

Methodology · Statistics 2021-02-16 Jason M. Whyte

Structural identifiability analysis determines whether the parameters of a mechanistic ordinary differential equation (ODE) model can be uniquely recovered from ideal observations and is therefore a fundamental prerequisite for reliable…

Methodology · Statistics 2026-05-20 Abdallah Alsammani