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Anomaly detection in images plays a significant role for many applications across all industries, such as disease diagnosis in healthcare or quality assurance in manufacturing. Manual inspection of images, when extended over a monotonously…

Computer Vision and Pattern Recognition · Computer Science 2021-07-21 Vincent Wilmet , Sauraj Verma , Tabea Redl , Håkon Sandaker , Zhenning Li

Anomaly detection in medical imaging is essential for identifying rare pathological conditions, particularly when annotated abnormal samples are limited. We propose a hybrid anomaly detection framework that integrates self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Pritam Kar , Gouri Lakshmi S , Saptarshi Bej

Chest X-ray (CXR) is the most typical radiological exam for diagnosis of various diseases. Due to the expensive and time-consuming annotations, detecting anomalies in CXRs in an unsupervised fashion is very promising. However, almost all of…

Image and Video Processing · Electrical Eng. & Systems 2022-06-30 Yu Cai , Hao Chen , Xin Yang , Yu Zhou , Kwang-Ting Cheng

We present a weakly supervised deep learning model for classifying thoracic diseases and identifying abnormalities in chest radiography. In this work, instead of learning from medical imaging data with region-level annotations, our model…

Computer Vision and Pattern Recognition · Computer Science 2018-11-07 Bo Zhou , Yuemeng Li , Jiangcong Wang

Radiography imaging protocols focus on particular body regions, therefore producing images of great similarity and yielding recurrent anatomical structures across patients. Exploiting this structured information could potentially ease the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Tiange Xiang , Yixiao Zhang , Yongyi Lu , Alan Yuille , Chaoyi Zhang , Weidong Cai , Zongwei Zhou

Anomaly detection is a field of intense research. Identifying low probability events in data/images is a challenging problem given the high-dimensionality of the data, especially when no (or little) information about the anomaly is…

Machine Learning · Computer Science 2022-04-13 José A. Padrón-Hidalgo , Valero Laparra , Gustau Camps-Valls

We propose a hierarchically structured variational inference model for accurately disentangling observable evidence of disease (e.g. brain lesions or atrophy) from subject-specific anatomy in brain MRIs. With flexible, partially…

Computer Vision and Pattern Recognition · Computer Science 2022-11-17 Anjun Hu , Jean-Pierre R. Falet , Brennan S. Nichyporuk , Changjian Shui , Douglas L. Arnold , Sotirios A. Tsaftaris , Tal Arbel

Universal anomaly detection still remains a challenging problem in machine learning and medical image analysis. It is possible to learn an expected distribution from a single class of normative samples, e.g., through epistemic uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Johanna P. Müller , Matthew Baugh , Jeremy Tan , Mischa Dombrowski , Bernhard Kainz

Anomaly detection methods can be very useful in identifying interesting or concerning events. In this work, we develop and examine new probabilistic anomaly detection methods that let us evaluate management decisions for a specific patient…

Machine Learning · Computer Science 2026-05-07 Milos Hauskrecht , Michal Valko , Branislav Kveton , Shyam Visweswaran , Gregory Cooper

Anomaly detection in spatiotemporal data is a challenging problem encountered in a variety of applications, including video surveillance, medical imaging data, and urban traffic monitoring. Existing anomaly detection methods focus mainly on…

Machine Learning · Computer Science 2025-10-02 Rachita Mondal , Mert Indibi , Tapabrata Maiti , Selin Aviyente

Anomaly detection (AD) is a crucial task in machine learning with various applications, such as detecting emerging diseases, identifying financial frauds, and detecting fake news. However, obtaining complete, accurate, and precise labels…

Machine Learning · Computer Science 2023-02-10 Minqi Jiang , Chaochuan Hou , Ao Zheng , Xiyang Hu , Songqiao Han , Hailiang Huang , Xiangnan He , Philip S. Yu , Yue Zhao

Harnessing the power of deep neural networks in the medical imaging domain is challenging due to the difficulties in acquiring large annotated datasets, especially for rare diseases, which involve high costs, time, and effort for…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Md Mahfuzur Rahman Siddiquee , Jay Shah , Teresa Wu , Catherine Chong , Todd J. Schwedt , Gina Dumkrieger , Simona Nikolova , Baoxin Li

Anomaly detection is an emerging approach in digital pathology for its ability to efficiently and effectively utilize data for disease diagnosis. While supervised learning approaches deliver high accuracy, they rely on extensively annotated…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jiamu Wang , Keunho Byeon , Jinsol Song , Anh Nguyen , Sangjeong Ahn , Sung Hak Lee , Jin Tae Kwak

Fine-grained anomaly detection has recently been dominated by segmentation based approaches. These approaches first classify each element of the sample (e.g., image patch) as normal or anomalous and then classify the entire sample as…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Niv Cohen , Issar Tzachor , Yedid Hoshen

This review explores anomaly localization in medical images using denoising diffusion models. After providing a brief methodological background of these models, including their application to image reconstruction and their conditioning…

Image and Video Processing · Electrical Eng. & Systems 2025-12-15 Cosmin I. Bercea , Philippe C. Cattin , Julia A. Schnabel , Julia Wolleb

Medical imaging data suffers from the limited availability of annotation because annotating 3D medical data is a time-consuming and expensive task. Moreover, even if the annotation is available, supervised learning-based approaches suffer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Abinav Ravi Venkatakrishnan , Seong Tae Kim , Rami Eisawy , Franz Pfister , Nassir Navab

Supervised machine learning has enabled accurate pathology detection in brain MRI, but requires training data from diseased subjects that may not be readily available in some scenarios, for example, in the case of rare diseases.…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Ana Lawry Aguila , Peirong Liu , Oula Puonti , Juan Eugenio Iglesias

Recently anomaly detection has drawn much attention in diagnosing ocular diseases. Most existing anomaly detection research in fundus images has relatively large anomaly scores in the salient retinal structures, such as blood vessels,…

Computer Vision and Pattern Recognition · Computer Science 2023-12-29 Jingqi Niu , Shiwen Dong , Qinji Yu , Kang Dang , Xiaowei Ding

In this paper, we present a memory-augmented algorithm for anomaly detection. Classical anomaly detection algorithms focus on learning to model and generate normal data, but typically guarantees for detecting anomalous data are weak. The…

Machine Learning · Computer Science 2020-02-10 Ziyi Yang , Teng Zhang , Iman Soltani Bozchalooi , Eric Darve

Recent work has shown that label-efficient few-shot learning through self-supervision can achieve promising medical image segmentation results. However, few-shot segmentation models typically rely on prototype representations of the…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Stine Hansen , Srishti Gautam , Robert Jenssen , Michael Kampffmeyer