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Physicians work at a very tight schedule and need decision-making support tools to help on improving and doing their work in a timely and dependable manner. Examining piles of sheets with test results and using systems with little…

Discovering research expertise at universities can be a difficult task. Directories routinely become outdated, and few help in visually summarizing researchers' work or supporting the exploration of shared interests among researchers. This…

Digital Libraries · Computer Science 2020-09-02 Jon Saad-Falcon , Omar Shaikh , Zijie J. Wang , Austin P. Wright , Sasha Richardson , Duen Horng Chau

Artificial Intelligence (AI) brings advancements to support pathologists in navigating high-resolution tumor images to search for pathology patterns of interest. However, existing AI-assisted tools have not realized this promised potential…

Eosinophilic Esophagitis (EoE) is a chronic, immune/antigen-mediated esophageal disease, characterized by symptoms related to esophageal dysfunction and histological evidence of eosinophil-dominant inflammation. Owing to the intricate…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Juming Xiong , Yilin Liu , Ruining Deng , Regina N Tyree , Hernan Correa , Girish Hiremath , Yaohong Wang , Yuankai Huo

Eosinophilic esophagitis (EoE) is a chronic esophageal disorder marked by eosinophil-dominated inflammation. Diagnosing EoE usually involves endoscopic inspection of the esophageal mucosa and obtaining esophageal biopsies for histologic…

Image and Video Processing · Electrical Eng. & Systems 2025-02-07 Juming Xiong , Hou Xiong , Quan Liu , Ruining Deng , Regina N Tyree , Girish Hiremath , Yuankai Huo

Pathological is crucial to cancer diagnosis. Usually, Pathologists draw their conclusion based on observed cell and tissue structure on histology slides. Rapid development in machine learning, especially deep learning have established…

Image and Video Processing · Electrical Eng. & Systems 2020-01-15 Jiangbo Shi , Zeyu Gao , Haichuan Zhang , Pargorn Puttapirat , Chunbao Wang , Xiangrong Zhang , Chen Li

Application of deep learning on histopathological whole slide images (WSIs) holds promise of improving diagnostic efficiency and reproducibility but is largely dependent on the ability to write computer code or purchase commercial…

Deep learning has remarkably advanced in the last few years, supported by large labeled data sets. These data sets are precious yet scarce because of the time-consuming labeling procedures, discouraging researchers from producing them. This…

Computer Vision and Pattern Recognition · Computer Science 2022-03-31 Bernardo Silva , Laís Pinheiro , Brenda Sobrinho , Fernanda Lima , Bruna Sobrinho , Kalyf Abdalla , Matheus Pithon , Patrícia Cury , Luciano Oliveira

The discovery of patterns associated with diagnosis, prognosis, and therapy response in digital pathology images often requires intractable labeling of large quantities of histological objects. Here we release an open-source labeling tool,…

Acquiring structured data from domain-specific, image-based documents such as scanned reports is crucial for many downstream tasks but remains challenging due to document variability. Many of these documents exist as images rather than as…

Software Engineering · Computer Science 2025-05-07 Qiang Sun , Sirui Li , Tingting Bi , Du Huynh , Mark Reynolds , Yuanyi Luo , Wei Liu

Context: Analyzing digital pathology images is necessary to draw diagnostic conclusions by investigating tissue patterns and cellular morphology. However, manual evaluation can be time-consuming, expensive, and prone to inter- and…

Image and Video Processing · Electrical Eng. & Systems 2023-07-26 Kimia Hemmatirad , Morteza Babaie , Jeffrey Hodgin , Liron Pantanowitz , H. R. Tizhoosh

Purpose: Exercise-induced pulmonary hemorrhage (EIPH) is a common syndrome in sport horses with negative impact on performance. Cytology of bronchoalveolar lavage fluid by use of a scoring system is considered the most sensitive diagnostic…

Graph Neural Networks (GNNs) have recently been found to excel in histopathology. However, an important histopathological task, where GNNs have not been extensively explored, is the classification of glomeruli health as an important…

Artificial intelligence (AI) has transformed digital pathology by enabling biomarker prediction from high-resolution whole-slide images (WSIs). However, current methods are computationally inefficient, processing thousands of redundant…

While high-resolution pathology images lend themselves well to `data hungry' deep learning algorithms, obtaining exhaustive annotations on these images is a major challenge. In this paper, we propose a self-supervised CNN approach to…

Computer Vision and Pattern Recognition · Computer Science 2020-08-14 Navid Alemi Koohbanani , Balagopal Unnikrishnan , Syed Ali Khurram , Pavitra Krishnaswamy , Nasir Rajpoot

Whole-slide image (WSI) preprocessing, comprising tissue detection followed by patch extraction, is foundational to AI-driven computational pathology but remains a major bottleneck for scaling to large and heterogeneous cohorts. We present…

Attention guidance is an approach to addressing dataset bias in deep learning, where the model relies on incorrect features to make decisions. Focusing on image classification tasks, we propose an efficient human-in-the-loop system to…

Computer Vision and Pattern Recognition · Computer Science 2023-02-07 Yi He , Xi Yang , Chia-Ming Chang , Haoran Xie , Takeo Igarashi

Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology. However, whole-slide imaging (WSI) poses a complex computer vision problem…

Background: Recruitment for cohorts involving complex liver diseases, such as hepatocellular carcinoma and liver cirrhosis, often requires interpreting semantically complex criteria. Traditional manual screening methods are time-consuming…

Artificial Intelligence · Computer Science 2025-02-27 Xiongbin Gui , Hanlin Lv , Xiao Wang , Longting Lv , Yi Xiao , Lei Wang

Recent advances in whole slide imaging (WSI) technology have led to the development of a myriad of computer vision and artificial intelligence (AI) based diagnostic, prognostic, and predictive algorithms. Computational Pathology (CPath)…