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Clustering is an unsupervised machine learning methodology where unlabeled elements/objects are grouped together aiming to the construction of well-established clusters that their elements are classified according to their similarity. The…

Machine Learning · Statistics 2023-10-20 Dimitrios Saligkaras , Vasileios E. Papageorgiou

Bio image analysis has recently become one keystone of biological research but biologists tend to get lost in a plethora of available software and the way to adjust available tools to their own image analysis problem. We present BIII,…

Clustering is a popular data mining technique that aims to partition an input space into multiple homogeneous regions. There exist several clustering algorithms in the literature. The performance of a clustering algorithm depends on its…

Human-Computer Interaction · Computer Science 2020-08-20 Sudip Poddar , Anirban Mukhopadhyay

Low-dimensional embeddings are widely used as visual summaries of high-dimensional data and to enable downstream scientific discoveries. Yet, popular nonlinear dimension reduction methods, such as t-SNE and UMAP, are often selected based on…

Machine Learning · Statistics 2026-05-29 Irene Chang , Tarek M. Zikry , Genevera I. Allen

The primary goal in cluster analysis is to discover natural groupings of objects. The field of cluster analysis is crowded with diverse methods that make special assumptions about data and address different scientific aims. Despite its…

Genomics · Quantitative Biology 2018-06-07 Gary K. Chen , Eric Chi , John Ranola , Kenneth Lange

Developing an understanding of high-dimensional data can be facilitated by visualizing that data using dimensionality reduction. However, the low-dimensional embeddings are often difficult to interpret. To facilitate the exploration and…

Machine Learning · Computer Science 2025-04-16 Fuyin Lai , Edith Heiter , Guillaume Bied , Jefrey Lijffijt

Biologists often perform clustering analysis to derive meaningful patterns, relationships, and structures from data instances and attributes. Though clustering plays a pivotal role in biologists' data exploration, it takes non-trivial…

Human-Computer Interaction · Computer Science 2019-11-05 Bahador Saket , Subhajit Das , Bum Chul Kwon , Alex Endert

In many biomedical research, multiple views of data (e.g., genomics, proteomics) are available, and a particular interest might be the detection of sample subgroups characterized by specific groups of variables. Biclustering methods are…

Methodology · Statistics 2021-11-12 W. Zhang , C. Wendt , R. Bowler , C. P. Hersh , S. E. Safo

Biclustering is a two way clustering approach involving simultaneous clustering along two dimensions of the data matrix. Finding biclusters of web objects (i.e. web users and web pages) is an emerging topic in the context of web usage…

Neural and Evolutionary Computing · Computer Science 2011-06-14 R. Rathipriya , Dr. K. Thangavel , J. Bagyamani

This paper presents a novel enumerative biclustering algorithm to directly mine all maximal biclusters in mixed-attribute datasets (containing both numerical and categorical attributes), with or without missing values. The proposal is an…

Databases · Computer Science 2017-10-11 Rosana Veroneze , Fernando J. Von Zuben

While machine learning offers diverse techniques suitable for exploring various medical research questions, a cohesive synergistic framework can facilitate the integration and understanding of new approaches within unified model development…

Machine Learning · Computer Science 2025-01-09 Ramtin Zargari Marandi , Anne Svane Frahm , Jens Lundgren , Daniel Dawson Murray , Maja Milojevic

Clustering aims to group unlabelled samples based on their similarities. It has become a significant tool for the analysis of high-dimensional data. However, most of the clustering methods merely generate pseudo labels and thus are unable…

Artificial Intelligence · Computer Science 2023-06-21 Tianyi Huang , Shenghui Cheng , Stan Z. Li , Zhengjun Zhang

Clustering is an unsupervised learning problem that aims to partition unlabelled data points into groups with similar features. Traditional clustering algorithms provide limited insight into the groups they find as their main focus is…

Machine Learning · Computer Science 2022-10-18 Connor Lawless , Oktay Gunluk

Virtual cell modeling aims to predict cellular responses to perturbations. Existing virtual cell models rely heavily on large-scale single-cell datasets, learning explicit mappings between gene expression and perturbations. Although recent…

Cell Behavior · Quantitative Biology 2026-03-02 Zhijian Wei , Runze Ma , Zichen Wang , Zhongmin Li , Shuotong Song , Shuangjia Zheng

Complementary-label learning (CLL) is a weakly supervised paradigm where instances are labeled with classes they do not belong to. Despite a decade of research, CLL methods remain competitive mainly on 10-class classification, with scaling…

Machine Learning · Computer Science 2026-05-19 Tan-Ha Mai , Chao-Kai Chiang , Han-Hwa Shih , Gang Niu , Masashi Sugiyama , Hsuan-Tien Lin

Biclustering is a problem in machine learning and data mining that seeks to group together rows and columns of a dataset according to certain criteria. In this work, we highlight the natural relation that quantum computing models like boson…

Quantum Physics · Physics 2024-05-30 Ajinkya Borle , Ameya Bhave

Clustering is an unsupervised technique of Data Mining. It means grouping similar objects together and separating the dissimilar ones. Each object in the data set is assigned a class label in the clustering process using a distance measure.…

Information Retrieval · Computer Science 2011-10-13 Parul Agarwal , M. Afshar Alam , Ranjit Biswas

Interactive data visualization is a major part of modern exploratory data analysis, with web-based technologies enabling a rich ecosystem of both specialized and general tools. However, current visualization tools often lack support for…

Human-Computer Interaction · Computer Science 2025-08-14 Jan Simson

When faced with new data, we often conduct a cluster analysis to obtain a better understanding of the data's structure and the archetypical samples present in the data. This process often includes visualization of the data, either as a way…

Applications · Statistics 2026-04-06 Justin Lin , Julia Fukuyama

The lack of freely available (real-life or synthetic) high or ultra-high dimensional, multi-class datasets may hamper the rapidly growing research on feature screening, especially in the field of biometrics, where the usage of such datasets…