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Detecting microbial biomarkers used to predict disease phenotypes and clinical outcomes is crucial for disease early-stage screening and diagnosis. Most methods for biomarker identification are linear-based, which is very limited as…

Quantitative Methods · Quantitative Biology 2021-09-29 Jian Jiang

Data analysis plays an indispensable role for value creation in industry. Cluster analysis in this context is able to explore given datasets with little or no prior knowledge and to identify unknown patterns. As (big) data complexity…

Machine Learning · Computer Science 2021-06-25 Marc Wegmann , Domenique Zipperling , Jonas Hillenbrand , Jürgen Fleischer

Feature selection is a fundamental machine learning and data mining task, involved with discriminating redundant features from informative ones. It is an attempt to address the curse of dimensionality by removing the redundant features,…

Machine Learning · Computer Science 2026-05-28 Muhammad Rajabinasab , Arthur Zimek

Biclustering is a powerful approach to search for patterns in data, as it can be driven by a function that measures the quality of diverse types of patterns of interest. However, due to its computational complexity, the exploration of the…

Machine Learning · Computer Science 2021-04-27 Marcin Michalak , Jesús S. Aguilar-Ruiz

In this paper, we present Pilaster (https://visusal.github.io/pilaster/), a collection of citation metadata extracted from publications in visualization for the digital humanities. The collection is generated from a seed set of relevant…

Human-Computer Interaction · Computer Science 2020-09-08 Alejandro Benito-Santos , Roberto Therón

In many situations it is desirable to identify clusters that differ with respect to only a subset of features. Such clusters may represent homogeneous subgroups of patients with a disease, such as cancer or chronic pain. We define a…

Methodology · Statistics 2014-07-14 Qian Liu , Guanhua Chen , Michael R. Kosorok , Eric Bair

Biclustering, the process of simultaneously clustering the rows and columns of a data matrix, is a popular and effective tool for finding structure in a high-dimensional dataset. Many biclustering procedures appear to work well in practice,…

Methodology · Statistics 2020-06-04 Cheryl J. Flynn , Patrick O. Perry

Visualization of multidimensional, categorical data is a common challenge across scientific areas and, in particular, the life sciences. The goal is to create a comprehensive overview of the underlying data which allows to assess multiple…

Quantitative Methods · Quantitative Biology 2025-06-19 Matthias Flotho , Philipp Flotho , Andreas Keller

Motivation: In this paper we present the latest release of EBIC, a next-generation biclustering algorithm for mining genetic data. The major contribution of this paper is adding support for big data, making it possible to efficiently run…

Genomics · Quantitative Biology 2024-09-05 Patryk Orzechowski , Jason H. Moore

In recent years, with the development of microarray technique, discovery of useful knowledge from microarray data has become very important. Biclustering is a very useful data mining technique for discovering genes which have similar…

Computational Engineering, Finance, and Science · Computer Science 2009-09-09 Mohsen lashkargir , S. Amirhassan Monadjemi , Ahmad Baraani Dastjerdi

IDEAL (Influence Diagram Evaluation and Analysis in Lisp) is a software environment for creation and evaluation of belief networks and influence diagrams. IDEAL is primarily a research tool and provides an implementation of many of the…

Artificial Intelligence · Computer Science 2013-04-05 Sampath Srinivas , John S. Breese

In complex multivariate data sets, different features usually include diverse associations with different variables, and different variables are associated within different regions. Therefore, exploring the associations between variables…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Xiangyang He , Yubo Tao , Qirui Wang , Hai Lin

In the biclustering problem, we seek to simultaneously group observations and features. While biclustering has applications in a wide array of domains, ranging from text mining to collaborative filtering, the problem of identifying…

Methodology · Statistics 2018-06-07 Eric C. Chi , Genevera I. Allen , Richard G. Baraniuk

Biclustering involves the simultaneous clustering of objects and their attributes, thus defining local two-way clustering models. Recently, efficient algorithms were conceived to enumerate all biclusters in real-valued datasets. In this…

Machine Learning · Computer Science 2015-06-04 Saullo Haniell Galvão de Oliveira , Rosana Veroneze , Fernando José Von Zuben

The increased interest in deep learning applications, and their hard-to-detect biases result in the need to validate and explain complex models. However, current explanation methods are limited as far as both the explanation of the…

Computer Vision and Pattern Recognition · Computer Science 2023-01-05 Weronika Hryniewska , Adrianna Grudzień , Przemysław Biecek

Synthetic biology brings together concepts and techniques from engineering and biology. In this field, computer-aided design (CAD) is necessary in order to bridge the gap between computational modeling and biological data. An application…

Molecular Networks · Quantitative Biology 2009-07-24 Deepak Chandran , Frank T. Bergmann , Herbert M. Sauro

Machine learning (ML) offers a collection of powerful approaches for detecting and modeling associations, often applied to data having a large number of features and/or complex associations. Currently, there are many tools to facilitate…

Human-in-the-loop data analysis applications necessitate greater transparency in machine learning models for experts to understand and trust their decisions. To this end, we propose a visual analytics workflow to help data scientists and…

Machine Learning · Statistics 2017-10-03 Josua Krause , Aritra Dasgupta , Jordan Swartz , Yindalon Aphinyanaphongs , Enrico Bertini

To understand complex biological systems, the research community has produced huge corpus of gene expression data. A large number of clustering approaches have been proposed for the analysis of gene expression data. However, extracting…

Computational Engineering, Finance, and Science · Computer Science 2010-03-28 Swathi. H

Given a set of data, biclustering aims at finding simultaneous partitions in biclusters of its samples and of the features which are used for representing the samples. Consistent biclusterings allow to obtain correct classifications of the…

Machine Learning · Computer Science 2010-03-18 Antonio Mucherino , Sonia Cafieri