Related papers: Hepatitis C Virus Epidemic Control Using a Nonline…
The aims of this work is to analyse of the global stability of the extended model of hepatitis C virus(HCV) infection with cellular proliferation, spontaneous cure and hepatocyte homeostasis. We first give general information about…
In this article, the feasibility of using optimal control theory will be studied to develop control theoretic methods for personalized treatment of HCV patients. The mathematical model for HCV progression includes compartments for healthy…
We propose a Markov model for the spread of Hepatitis C virus (HCV) among drug users who use injections. We then proceed to an asymptotic analysis (large initial population) and show that the Markov process is close to the solution of a non…
In this paper, a mathematical analysis of the global dynamics of a partial differential equation viral infection cellular model is carried out. We study the dynamics of a hepatitis C virus (HCV) model, under therapy, that considers both…
A mathematical modeling of Hepatitis C Virus (HCV) dynamics has been presented in this paper. The proposed model, which involves four coupled ordinary differential equations, describes the interaction of target cells (hepatocytes), infected…
Viral hepatitis is the regularly found health problem throughout the world among other easily transmitted diseases, such as tuberculosis, human immune virus, malaria and so on. Among all hepatitis viruses, the uppermost numbers of deaths…
Hepatitis type B is one of the most common infectious disease worldwide that can pose severe threats to human health up to the point that may contribute to severe liver damage or cancer. Over the past two decades a large number of dynamic…
Decision-makers frequently must choose a single action from a finite set of alternatives -- for example, physicians selecting a treatment, investors choosing a portfolio risk level, or judges determining sentences. To improve outcomes,…
We propose and study a new mathematical model of the human immunodeficiency virus (HIV). The main novelty is to consider that the antibody growth depends not only on the virus and on the antibodies concentration but also on the uninfected…
Equipment sharing among people who inject drugs (PWID) is a key risk factor in infection by hepatitis C virus (HCV). Both the effectiveness and cost-effectiveness of interventions aimed at reducing HCV transmission in this population (such…
This study presents an improved mathematical model for Hepatitis B Virus (HBV) transmission dynamics by investigating autonomous and nonautonomous cases. The novel model incorporates the effects of medical treatment, allowing for a more…
Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus (HBV). In this paper, the transmission dynamics of hepatitis B is formulated with a mathematical model with considerations of different classes of…
Viral sequence classification is an important task in pathogen detection, epidemiological surveys and evolutionary studies. Statistical learning methods are widely used to classify and identify viral sequences in samples from environments.…
Hepatitis C virus (HCV) is a widely spread disease all over the world. HCV has very high mutation rate that makes it resistant to antibodies. Modeling HCV to identify the virus mutation process is essential to its detection and predicting…
Background: Highly effective direct-acting antiviral (DAA) regimens (90% efficacy) are becoming available for hepatitis C virus (HCV) treatment. This therapeutic revolution leads us to consider possibility of eradicating the virus. However,…
Hepatitis C virus (HCV) infection is endemic in people who inject drugs (PWID), with prevalence estimates above 60 percent for PWID in the United States. Previous modeling studies suggest that direct acting antiviral (DAA) treatment can…
We consider a mathematical model comprising of four coupled ordinary differential equations (ODEs) for studying the hepatitis C (HCV) viral dynamics. The model embodies the efficacies of a combination therapy of interferon and ribavirin. A…
In this paper, we present the global analysis of a HCV model under therapy. We prove that the solutions with positive initial values are global, positive, bounded and not display periodic orbits. In addition, we show that the model is…
This study demonstrates the implementation of the stochastic ruler discrete simulation optimization method for calibrating an agent-based model (ABM) developed to simulate hepatitis C virus (HCV) transmission. The ABM simulates HCV…
Hepatitis B virus (HBV) is considered as etiological agent of the lethal liver disease hepatitis B. Globally, hepatitis B is recognized as one of the prevailing infectious diseases with a significant impact on human health. In spite of…