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Total internal reflection fluorescence microscopy (TIRF) has enabled low-background, live-cell friendly imaging of cell surfaces and other thin samples thanks to the shallow penetration of the evanescent light field into the sample. The…

Inspired by the capability of structured illumination microscopy in subwavelength imaging, many researchers devoted themselves to investigating this methodology. However, due to the free propagating feature of the traditional structured…

Extending super-resolution imaging techniques to objects hidden in strongly scattering media potentially revolutionize the technical analysis for much broader categories of samples, such as biological tissues. The main challenge is the…

Multimode fibers recently emerged as compact minimally-invasive probes for high-resolution deep-tissue imaging. However, the commonly used silica fibers have a relatively low numerical aperture (NA) limiting the spatial resolution of a…

Optics · Physics 2024-07-09 Zhouping Lyu , Lyubov Amitonova

Single Pixel (SP) imaging is now a reality in many applications, e.g., biomedical ultrathin endoscope and fluorescent spectroscopy. In this context, many schemes exist to improve the light throughput of these device, e.g., using structured…

Computer Vision and Pattern Recognition · Computer Science 2019-02-19 Amirafshar Moshtaghpour , José M. Bioucas-Dias , Laurent Jacques

Second harmonic generation microscopy (SHG) is a powerful imaging modality which has found applications in investigating both biological and synthetic nanostructures. Like all optical microscopy techniques, the resolution of SHG is limited…

We propose a method of spatial resolution enhancement in metrology (thermometry, magnetometry, pH estimation, and similar methods) with blinking fluorescent nanosensors by combining sensing with super-resolution optical fluctuation imaging…

Optics · Physics 2026-05-11 Alexander Mikhalychev , Alex Ulyanenkov

Wavefront-shaping is a promising approach for imaging fluorescent targets deep inside scattering tissue despite strong aberrations. It enables focusing an incoming illumination into a single spot inside tissue, as well as correcting the…

Optics · Physics 2024-01-23 Dror Aizik , Anat Levin

Evanescent-wave microscopy achieves sub-diffraction axial sectioning by confining fluorescence excitation to a thin layer close to the cell/substrate interface. How thin this light sheet exactly is, however, is often unknown. Particularly…

Biological Physics · Physics 2013-02-08 Maia Brunstein , Maxime Teremetz , Christophe Tourain , Martin Oheim

Historically, functional magnetic resonance imaging (fMRI) of the brain has focused primarily on gray matter, particularly the cortical gray matter and associated nuclei. However, recent work has demonstrated that functional activity in…

Medical Physics · Physics 2025-07-10 Zhiyuan Li , Kurt G. Schilling , Bennett A. Landman

3D super-resolution fluorescence microscopy typically requires sophisticated setups, sample preparation, or long measurements. A notable exception, SOFI, only requires recording a sequence of frames and no hardware modifications whatsoever…

Optics · Physics 2024-03-01 Pawel Szczypkowski , Monika Pawlowska , Radek Lapkiewicz

The resolving ability of widefield fluorescence microscopy is fundamentally limited by out-of-focus background owing to its low axial resolution, particularly for densely labeled biological samples. Although total internal reflection…

Structured illumination microscopy (SIM) enables live cell, super-resolution imaging at high speeds. SIM uses sophisticated optical systems to generate pre-determined excitation light patterns, and reconstruction algorithms to enhance the…

This paper introduces a single-pixel HyperSpectral (HS) imaging framework based on Fourier Transform Interferometry (FTI). By combining a space-time coding of the light illumination with partial interferometric observations of a collimated…

Computer Vision and Pattern Recognition · Computer Science 2018-09-05 Amirafshar Moshtaghpour , José M. Bioucas-Dias , Laurent Jacques

In the recent years, heterogeneous machine learning accelerators have become of significant interest in science, engineering and industry. The major processing speed bottlenecks in these platforms come from (a) an electronic data…

Optics · Physics 2022-08-25 Maria Solyanik-Gorgone , Behrouz Movahhed , Volker J Sorger

Artificial intelligence has emerged as promising tool to decode a phase image transmitted through a multimode fiber (MMF) by applying deep learning techniques. By transmitting tens of thousands of images through the MMF, deep neural…

Near-field infrared spectroscopy by elastic scattering of light from a probe tip resolves optical contrasts in materials at dramatically sub-wavelength scales across a broad energy range, with the demonstrated capacity for chemical…

In recent years, computational Time-of-Flight (ToF) imaging has emerged as an exciting and a novel imaging modality that offers new and powerful interpretations of natural scenes, with applications extending to 3D, light-in-flight, and…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Ruiming Guo , Ayush Bhandari

We propose a fusion algorithm for haze removal that combines color information from an RGB image and edge information extracted from its corresponding NIR image using Haar wavelets. The proposed algorithm is based on the key observation…

Computer Vision and Pattern Recognition · Computer Science 2022-04-15 Sumit Laha , Ankit Sharma , Shengnan Hu , Hassan Foroosh

Neuromorphic chip refers to an unconventional computing architecture that is modelled on biological brains. It is ideally suited for processing sensory data for intelligence computing, decision-making or context cognition. Despite rapid…

Emerging Technologies · Computer Science 2016-09-09 Shuchao Qin , Fengqiu Wang , Yujie Liu , Qing Wan , Xinran Wang , Yongbing Xu , Yi Shi , Xiaomu Wang , Rong Zhang
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