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Large-scale clinical data is invaluable to driving many computational scientific advances today. However, understandable concerns regarding patient privacy hinder the open dissemination of such data and give rise to suboptimal siloed…

Computation and Language · Computer Science 2019-05-23 Oren Melamud , Chaitanya Shivade

Single nucleotide polymorphism (SNP) datasets are fundamental to genetic studies but pose significant privacy risks when shared. The correlation of SNPs with each other makes strong adversarial attacks such as masked-value reconstruction,…

Machine Learning · Computer Science 2025-10-08 Shadi Rahimian , Mario Fritz

The availability of genomic data is essential to progress in biomedical research, personalized medicine, etc. However, its extreme sensitivity makes it problematic, if not outright impossible, to publish or share it. As a result, several…

Genomics · Quantitative Biology 2022-01-19 Bristena Oprisanu , Georgi Ganev , Emiliano De Cristofaro

Deep learning models have demonstrated superior performance in several application problems, such as image classification and speech processing. However, creating a deep learning model using health record data requires addressing certain…

Machine Learning · Computer Science 2021-12-14 Amirsina Torfi , Edward A. Fox , Chandan K. Reddy

Preservation of private user data is of paramount importance for high Quality of Experience (QoE) and acceptability, particularly with services treating sensitive data, such as IT-based health services. Whereas anonymization techniques were…

Machine Learning · Computer Science 2024-03-04 Navid Ashrafi , Vera Schmitt , Robert P. Spang , Sebastian Möller , Jan-Niklas Voigt-Antons

The recent availability of electronic health records (EHRs) have provided enormous opportunities to develop artificial intelligence (AI) algorithms. However, patient privacy has become a major concern that limits data sharing across…

Machine Learning · Computer Science 2023-02-01 Jin Li , Benjamin J. Cairns , Jingsong Li , Tingting Zhu

The rapid growth in data availability has facilitated research and development, yet not all industries have benefited equally due to legal and privacy constraints. The healthcare sector faces significant challenges in utilizing patient data…

Methodology · Statistics 2025-11-18 Katariina Perkonoja , Kari Auranen , Joni Virta

Privacy-preserving synthetic data offers a promising solution to harness segregated data in high-stakes domains where information is compartmentalized for regulatory, privacy, or institutional reasons. This survey provides a comprehensive…

Cryptography and Security · Computer Science 2025-03-28 Viktor Schlegel , Anil A Bharath , Zilong Zhao , Kevin Yee

We focus on the problem of generating high-quality, private synthetic glucose traces, a task generalizable to many other time series sources. Existing methods for time series data synthesis, such as those using Generative Adversarial…

Machine Learning · Computer Science 2023-11-01 Josephine Lamp , Mark Derdzinski , Christopher Hannemann , Joost van der Linden , Lu Feng , Tianhao Wang , David Evans

The limited data availability due to strict privacy regulations and significant resource demands severely constrains biomedical time-series AI development, which creates a critical gap between data requirements and accessibility. Synthetic…

Machine Learning · Computer Science 2025-11-25 Youngjoon Lee , Seongmin Cho , Yehhyun Jo , Jinu Gong , Hyunjoo Jenny Lee , Joonhyuk Kang

Aggregate time-series data like traffic flow and site occupancy repeatedly sample statistics from a population across time. Such data can be profoundly useful for understanding trends within a given population, but also pose a significant…

Cryptography and Security · Computer Science 2022-01-14 Tatsuki Koga , Casey Meehan , Kamalika Chaudhuri

Facial recognition has become a widely used method for authentication and identification, with applications for secure access and locating missing persons. Its success is largely attributed to deep learning, which leverages large datasets…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Pedro Vidal , Bernardo Biesseck , Luiz E. L. Coelho , Roger Granada , David Menotti

Advances in generative models have transformed the field of synthetic image generation for privacy-preserving data synthesis (PPDS). However, the field lacks a comprehensive survey and comparison of synthetic image generation methods across…

Cryptography and Security · Computer Science 2025-06-27 Yunsung Chung , Yunbei Zhang , Nassir Marrouche , Jihun Hamm

Deep learning holds immense promise for aiding radiologists in breast cancer detection. However, achieving optimal model performance is hampered by limitations in availability and sharing of data commonly associated to patient privacy…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Richard Osuala , Daniel M. Lang , Anneliese Riess , Georgios Kaissis , Zuzanna Szafranowska , Grzegorz Skorupko , Oliver Diaz , Julia A. Schnabel , Karim Lekadir

Motivated by privacy concerns in long-term longitudinal studies in medical and social science research, we study the problem of continually releasing differentially private synthetic data from longitudinal data collections. We introduce a…

Data Structures and Algorithms · Computer Science 2024-05-28 Mark Bun , Marco Gaboardi , Marcel Neunhoeffer , Wanrong Zhang

Recent advancements in generative AI have made it possible to create synthetic datasets that can be as accurate as real-world data for training AI models, powering statistical insights, and fostering collaboration with sensitive datasets…

Machine Learning · Computer Science 2025-01-08 Amy Steier , Lipika Ramaswamy , Andre Manoel , Alexa Haushalter

Privacy concerns have attracted increasing attention in data-driven products due to the tendency of machine learning models to memorize sensitive training data. Generating synthetic versions of such data with a formal privacy guarantee,…

Computation and Language · Computer Science 2023-07-19 Xiang Yue , Huseyin A. Inan , Xuechen Li , Girish Kumar , Julia McAnallen , Hoda Shajari , Huan Sun , David Levitan , Robert Sim

Recent advances in deep generative models have greatly expanded the potential to create realistic synthetic health datasets. These synthetic datasets aim to preserve the characteristics, patterns, and overall scientific conclusions derived…

Machine Learning · Computer Science 2024-07-04 Jennifer A Bartell , Sander Boisen Valentin , Anders Krogh , Henning Langberg , Martin Bøgsted

Healthcare research and development face significant obstacles due to data scarcity and stringent privacy regulations, such as HIPAA and the GDPR, restricting access to essential real-world medical data. These limitations impede innovation,…

Machine Learning · Computer Science 2025-10-17 Md Ibrahim Shikder Mahin , Md Shamsul Arefin , Md Tanvir Hasan

Introduction: The amount of data generated by original research is growing exponentially. Publicly releasing them is recommended to comply with the Open Science principles. However, data collected from human participants cannot be released…

Machine Learning · Statistics 2023-10-11 Rémy Chapelle , Bruno Falissard