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Histopathology tissue analysis is considered the gold standard in cancer diagnosis and prognosis. Given the large size of these images and the increase in the number of potential cancer cases, an automated solution as an aid to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Mahendra Khened , Avinash Kori , Haran Rajkumar , Balaji Srinivasan , Ganapathy Krishnamurthi

Weakly supervised semantic segmentation (WSSS) in histopathology reduces pixel-level labeling by learning from image-level labels, but it is hindered by inter-class homogeneity, intra-class heterogeneity, and CAM-induced region shrinkage…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Khang Le , Anh Mai Vu , Thi Kim Trang Vo , Ha Thach , Ngoc Bui Lam Quang , Thanh-Huy Nguyen , Minh H. N. Le , Zhu Han , Chandra Mohan , Hien Van Nguyen

Cancer survival prediction is a challenging task that involves analyzing of the tumor microenvironment within Whole Slide Image (WSI). Previous methods cannot effectively capture the intricate interaction features among instances within the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Zekang Yang , Hong Liu , Xiangdong Wang

Learning high-quality, self-supervised, visual representations is essential to advance the role of computer vision in biomedical microscopy and clinical medicine. Previous work has focused on self-supervised representation learning (SSL)…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Cheng Jiang , Xinhai Hou , Akhil Kondepudi , Asadur Chowdury , Christian W. Freudiger , Daniel A. Orringer , Honglak Lee , Todd C. Hollon

Deep learning enables the modelling of high-resolution histopathology whole-slide images (WSI). Weakly supervised learning of tile-level data is typically applied for tasks where labels only exist on the patient or WSI level (e.g. patient…

Image and Video Processing · Electrical Eng. & Systems 2025-06-09 Abhinav Sharma , Bojing Liu , Mattias Rantalainen

Segment anything model (SAM) has emerged as the leading approach for zero-shot learning in segmentation tasks, offering the advantage of avoiding pixel-wise annotations. It is particularly appealing in medical image segmentation, where the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-29 Ziyi Huang , Hongshan Liu , Haofeng Zhang , Xueshen Li , Haozhe Liu , Fuyong Xing , Andrew Laine , Elsa Angelini , Christine Hendon , Yu Gan

Histopathological image classification is an important task in medical image analysis. Recent approaches generally rely on weakly supervised learning due to the ease of acquiring case-level labels from pathology reports. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Bodong Zhang , Hamid Manoochehri , Man Minh Ho , Fahimeh Fooladgar , Yosep Chong , Beatrice S. Knudsen , Deepika Sirohi , Tolga Tasdizen

The increasing availability of biomedical data is helping to design more robust deep learning (DL) algorithms to analyze biomedical samples. Currently, one of the main limitations to train DL algorithms to perform a specific task is the…

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

The existing barely-supervised medical image segmentation (BSS) methods, adopting a registration-segmentation paradigm, aim to learn from data with very few annotations to mitigate the extreme label scarcity problem. However, this paradigm…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Junming Su , Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane

Automated skin lesion segmentation through dermoscopic analysis is essential for early skin cancer detection, yet remains challenging due to limited annotated training data. We present MIRA-U, a semi-supervised framework that combines…

Image and Video Processing · Electrical Eng. & Systems 2025-10-20 Saqib Qamar

Noisy labels collected with limited annotation cost prevent medical image segmentation algorithms from learning precise semantic correlations. Previous segmentation arts of learning with noisy labels merely perform a pixel-wise manner to…

Computer Vision and Pattern Recognition · Computer Science 2022-06-17 Xiaoqing Guo , Yixuan Yuan

Counting mitotic figures is time-intensive for pathologists and leads to inter-observer variability. Artificial intelligence (AI) promises a solution by automatically detecting mitotic figures while maintaining decision consistency.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Seungho Choe , Xiaoli Qin , Abubakr Shafique , Amanda Dy , Susan Done , Dimitrios Androutsos , April Khademi

Computational pathology and whole-slide image (WSI) analysis are pivotal in cancer diagnosis and prognosis. However, the ultra-high resolution of WSIs presents significant modeling challenges. Recent advancements in pathology foundation…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Honglin Li , Zhongyi Shui , Yunlong Zhang , Chenglu Zhu , Lin Yang

Despite their superior performance, deep-learning methods often suffer from the disadvantage of needing large-scale well-annotated training data. In response, recent literature has seen a proliferation of efforts aimed at reducing the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Ji Yu

Accurate analysis of histopathological images is critical for disease diagnosis and treatment planning. Whole-slide images (WSIs), which digitize tissue specimens at gigapixel resolution, are fundamental to this process but require…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Enhui Chai , Sicheng Chen , Tianyi Zhang , Chad Wong , Kecheng Huang , Zeyu Liu , Fei Xia

Hyperspectral image (HSI) classification is a cornerstone of remote sensing, enabling precise material and land-cover identification through rich spectral information. While deep learning has driven significant progress in this task, small…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Weilian Zhou , Weixuan Xie , Sei-ichiro Kamata , Man Sing Wong , Huiying , Hou , Haipeng Wang

Recently, One-stage Weakly Supervised Semantic Segmentation (WSSS) with image-level labels has gained increasing interest due to simplification over its cumbersome multi-stage counterpart. Limited by the inherent ambiguity of Class…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Yuanchen Wu , Xichen Ye , Kequan Yang , Jide Li , Xiaoqiang Li

Deep neural networks have achieved remarkable success in a wide variety of natural image and medical image computing tasks. However, these achievements indispensably rely on accurately annotated training data. If encountering some…

Image and Video Processing · Electrical Eng. & Systems 2022-05-11 Cheng Xue , Lequan Yu , Pengfei Chen , Qi Dou , Pheng-Ann Heng

Weakly Supervised Semantic Segmentation (WSSS) is a challenging task aiming to learn the segmentation labels from class-level labels. In the literature, exploiting the information obtained from Class Activation Maps (CAMs) is widely used…

Computer Vision and Pattern Recognition · Computer Science 2022-11-24 Cenk Bircanoglu , Nafiz Arica
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