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Identification of clusters of co-expressed genes in transcriptomic data is a difficult task. Most algorithms used for this purpose can be classified into two broad categories: distance-based or model-based approaches. Distance-based…

Applications · Statistics 2022-09-26 Gabriel Lozano , Nadia Atallah , Michael Levine

We develop an iterative subsampling approach to improve the computational efficiency of our previous work on solution path clustering (SPC). The SPC method achieves clustering by concave regularization on the pairwise distances between…

Methodology · Statistics 2016-09-16 Yuliya Marchetti , Qing Zhou

Spectral clustering methods have gained widespread recognition for their effectiveness in clustering high-dimensional data. Among these techniques, constrained spectral clustering has emerged as a prominent approach, demonstrating enhanced…

Machine Learning · Computer Science 2024-04-05 Swarup Ranjan Behera , Vijaya V. Saradhi

Spectral clustering is a novel clustering method which can detect complex shapes of data clusters. However, it requires the eigen decomposition of the graph Laplacian matrix, which is proportion to $O(n^3)$ and thus is not suitable for…

Machine Learning · Computer Science 2013-07-02 Nguyen Lu Dang Khoa , Sanjay Chawla

The single-cell RNA sequencing (scRNA-seq) technology enables researchers to study complex biological systems and diseases with high resolution. The central challenge is synthesizing enough scRNA-seq samples; insufficient samples can impede…

Genomics · Quantitative Biology 2023-12-25 Yixuan Wang , Shuangyin Li , Shimin DI , Lei Chen

This paper aims at developing a clustering approach with spectral images directly from CASSI compressive measurements. The proposed clustering method first assumes that compressed measurements lie in the union of multiple low-dimensional…

Image and Video Processing · Electrical Eng. & Systems 2019-11-06 Jianchen Zhu , Tong Zhang , Shengjie Zhao , Carlos Hinojosa , Zengli Liu , Gonzalo R. Arce

Multi-manifold modeling is increasingly used in segmentation and data representation tasks in computer vision and related fields. While the general problem, modeling data by mixtures of manifolds, is very challenging, several approaches…

Computer Vision and Pattern Recognition · Computer Science 2012-10-08 G. Chen , S. Atev , G. Lerman

In this work, we propose a novel information theoretic framework for dictionary learning (DL) and sparse coding (SC) on a statistical manifold (the manifold of probability distributions). Unlike the traditional DL and SC framework, our new…

Computer Vision and Pattern Recognition · Computer Science 2017-02-06 Rudrasis Chakraborty , Monami Banerjee , Victoria Crawford , Baba C. Vemuri

Sparse Subspace Clustering (SSC) is a state-of-the-art method for clustering high-dimensional data points lying in a union of low-dimensional subspaces. However, while $\ell_1$ optimization-based SSC algorithms suffer from high…

Machine Learning · Computer Science 2018-02-14 Yanxi Chen , Gen Li , Yuantao Gu

We present a principled spectral approach to the well-studied constrained clustering problem. It reduces clustering to a generalized eigenvalue problem on Laplacians. The method works in nearly-linear time and provides concrete guarantees…

Social and Information Networks · Computer Science 2016-01-20 Mihai Cucuringu , Ioannis Koutis , Sanjay Chawla

In this paper, we consider nonsmooth composite optimization over compact embedded submanifolds defined by nonlinear equality constraints. We propose a feasibility-safeguarded inexact proximal linearized method (FSIPL), which allows…

Optimization and Control · Mathematics 2026-05-26 Xiyua Xie , Qia Li

We study Sparse Multiple Kernel Learning (SMKL), which is the problem of selecting a sparse convex combination of prespecified kernels for support vector binary classification. Unlike prevailing l1 regularized approaches that approximate a…

Machine Learning · Statistics 2025-12-03 Dimitris Bertsimas , Caio de Prospero Iglesias , Nicholas A. G. Johnson

Manifold learning is a central task in modern statistics and data science. Many datasets (cells, documents, images, molecules) can be represented as point clouds embedded in a high dimensional ambient space, however the degrees of freedom…

Machine Learning · Statistics 2025-02-18 Stephen Zhang , Gilles Mordant , Tetsuya Matsumoto , Geoffrey Schiebinger

We address the non-convex optimisation problem of finding a sparse matrix on the Stiefel manifold (matrices with mutually orthogonal columns of unit length) that maximises (or minimises) a quadratic objective function. Optimisation problems…

Optimization and Control · Mathematics 2021-10-04 Florian Bernard , Daniel Cremers , Johan Thunberg

Many approaches to transform classification problems from non-linear to linear by feature transformation have been recently presented in the literature. These notably include sparse coding methods and deep neural networks. However, many of…

Machine Learning · Computer Science 2015-07-08 Alessandro Montalto , Giovanni Tessitore , Roberto Prevete

Sparse principal component analysis (PCA), an important variant of PCA, attempts to find sparse loading vectors when conducting dimension reduction. This paper considers the nonsmooth Riemannian optimization problem associated with the…

Optimization and Control · Mathematics 2021-09-03 Wen Huang , Ke Wei

We present a new nonlinear dimensionality reduction method, MAPLE, that enhances UMAP by improving manifold modeling. MAPLE employs a self-supervised learning approach to more efficiently encode low-dimensional manifold geometry. Central to…

Machine Learning · Computer Science 2026-05-15 Zeyang Huang , Takanori Fujiwara , Angelos Chatzimparmpas , Wandrille Duchemin , Andreas Kerren

We propose a spectral clustering method based on local principal components analysis (PCA). After performing local PCA in selected neighborhoods, the algorithm builds a nearest neighbor graph weighted according to a discrepancy between the…

Machine Learning · Statistics 2019-04-09 Ery Arias-Castro , Gilad Lerman , Teng Zhang

Self-paced learning (SPL) mimics the cognitive process of humans, who generally learn from easy samples to hard ones. One key issue in SPL is the training process required for each instance weight depends on the other samples and thus…

Machine Learning · Computer Science 2018-07-09 Xuchao Zhang , Liang Zhao , Zhiqian Chen , Chang-Tien Lu

Sparse subspace clustering (SSC) is an elegant approach for unsupervised segmentation if the data points of each cluster are located in linear subspaces. This model applies, for instance, in motion segmentation if some restrictions on the…

Machine Learning · Statistics 2018-02-12 Hanno Ackermann , Michael Ying Yang , Bodo Rosenhahn