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Deep learning models achieve state-of-the art results in predicting blood glucose trajectories, with a wide range of architectures being proposed. However, the adaptation of such models in clinical practice is slow, largely due to the lack…

Machine Learning · Computer Science 2023-03-08 Renat Sergazinov , Mohammadreza Armandpour , Irina Gaynanova

We show that the output of systems with time-varying delay can exhibit a new kind of chaotic behavior characterized by laminar phases, which are periodically interrupted by irregular bursts. Within each laminar phase the output intensity…

Chaotic Dynamics · Physics 2022-02-22 David Müller , Andreas Otto , Günter Radons

Time delay is ubiquitous in many experimental and real-world situations. It is often unclear whether time delay plays a significant role in observed phenomena, and if it does, how long the time lag really is. This would be invaluable…

Data Analysis, Statistics and Probability · Physics 2025-12-10 Robin A. Kopp , Sabine H. L. Klapp , Deepak Gupta

Type 1 Diabetes (T1D) is a chronic condition where the body produces little or no insulin, a hormone required for the cells to use blood glucose (BG) for energy and to regulate BG levels in the body. Finding the right insulin dose and time…

Machine Learning · Computer Science 2024-11-28 Isabella Degen , Zahraa S. Abdallah

Real-world systems can be strongly influenced by time delays occurring in self-coupling interactions, due to unavoidable finite signal propagation velocities. When the delays become significantly long, complicated high-dimensional phenomena…

Chaotic Dynamics · Physics 2022-06-08 Serhiy Yanchuk , Giovanni Giacomelli

A type of chaos called laminar chaos was found in singularly perturbed dynamical systems with periodically [Phys. Rev. Lett. 120, 084102 (2018)] and quasiperiodically [Phys. Rev. E 107, 014205 (2023)] time-varying delay. Compared to…

Chaotic Dynamics · Physics 2025-08-29 David Müller-Bender , Rahil N. Valani

We introduce an approach which allows detecting causal relationships between variables for which the time evolution is available. Causality is assessed by a variational scheme based on the Information Imbalance of distance ranks, a…

Methodology · Statistics 2024-05-07 Vittorio Del Tatto , Gianfranco Fortunato , Domenica Bueti , Alessandro Laio

The chaotic spike train of a homoclinic dynamical system is self-synchronized by re-inserting a small fraction of the delayed output. Due to the sensitive nature of the homoclinic chaos to external perturbations, stabilization of very long…

Chaotic Dynamics · Physics 2009-11-07 F. T. Arecchi , R. Meucci , E. Allaria , A. Di Garbo , L. S. Tsimring

This thesis addresses the question of stability of systems defined by differential equations which contain nonlinearity and delay. In particular, we analyze the stability of a well-known delayed nonlinear implementation of a certain…

Dynamical Systems · Mathematics 2007-05-23 Matthew M. Peet

The spontaneous emergence of ordered structures, known as Turing patterns, in complex networks is a phenomenon that holds potential applications across diverse scientific fields, including biology, chemistry, and physics. Here, we present a…

Physics and Society · Physics 2023-09-26 Jiaying Zhou , Yong Ye , Alex Arenas , Sergio Gómez , Yi Zhao

Delayed processes are ubiquitous in biological systems and are often characterized by delay differential equations (DDEs) and their extension to include stochastic effects. DDEs do not explicitly incorporate intermediate states associated…

Quantitative Methods · Quantitative Biology 2016-09-28 Jingchen Feng , Stuart Sevier , Bin Huang , Dongya Jia , Herbert Levine

Reliable optimal control is challenging when the dynamics of a nonlinear system are unknown and only infrequent, noisy output measurements are available. This work addresses this setting of limited sensing by formulating a Bayesian prior…

Systems and Control · Electrical Eng. & Systems 2026-05-21 Robert Lefringhausen , Theodor Springer , Sandra Hirche

Delays in biological systems may be used to model events for which the underlying dynamics cannot be precisely observed. Mathematical modeling of biological systems with delays is usually based on Delay Differential Equations (DDEs), a kind…

Quantitative Methods · Quantitative Biology 2009-10-08 Roberto Barbuti , Giulio Caravagna , Paolo Milazzo , Andrea Maggiolo-Schettini

We study the possibility to stabilize unstable steady states and unstable periodic orbits in chaotic fractional-order dynamical systems by the time-delayed feedback method. By performing a linear stability analysis, we establish the…

General Physics · Physics 2011-07-07 Aleksandar Gjurchinovski , Trifce Sandev , Viktor Urumov

Real-world dynamical systems with retardation effects are described in general not by a single, precisely defined time delay, but by a range of delay times. An exact mapping onto a set of $N+1$ ordinary differential equations exists when…

Dynamical Systems · Mathematics 2023-08-16 Daniel Henrik Nevermann , Claudius Gros

External and internal factors may cause a system's parameter to vary with time before it stabilizes. This drift induces a regime shift when the parameter crosses a bifurcation. Here, we study the case of an infinite dimensional system: a…

Chaotic Dynamics · Physics 2020-10-14 Julia Cantisán , Jesús M. Seoane , Miguel A. F. Sanjuán

Model Predictive Controllers (MPC) require a good model for the controlled process. In this paper I infer inductive biases about a physical system. I use these biases to derive a new neural network architecture that can model this real…

Machine Learning · Computer Science 2021-04-26 Cristian Vicas

This paper studies input-to-state stability (ISS) of general nonlinear time-delay systems subject to delay-dependent impulse effects. Sufficient conditions for ISS are constructed by using the method of Lyapunov functionals. It is shown…

Optimization and Control · Mathematics 2022-06-09 Xinzhi Liu , Kexue Zhang

Quasi steady state assumptions are often used to simplify complex systems of ordinary differential equations in modelling of biochemical processes. The simplified system is designed to have the same qualitative properties as the original…

Dynamical Systems · Mathematics 2013-12-11 Tomáš Vejchodský

Dynamical systems with complex delayed interactions arise commonly when propagation times are significant, yielding complicated oscillatory instabilities. In this Letter, we introduce a class of systems with multiple, hierarchically long…

Pattern Formation and Solitons · Physics 2015-06-19 Serhiy Yanchuk , Giovanni Giacomelli