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Decision tree optimization is notoriously difficult from a computational perspective but essential for the field of interpretable machine learning. Despite efforts over the past 40 years, only recently have optimization breakthroughs been…

Machine Learning · Computer Science 2022-11-24 Jimmy Lin , Chudi Zhong , Diane Hu , Cynthia Rudin , Margo Seltzer

Functions of chemical composition are complex and discrete in nature making it impossible to optimize them with gradient methods. Genetic algorithms, which do not use derivative information, are used to maximize the thermal conductivity of…

Materials Science · Physics 2018-01-30 Alexander Kerr , Kieran Mullen

Coupling hemodynamics with vessel wall growth and remodeling (G&R) is crucial for understanding pathology at distal vasculature to study progression of incurable vascular diseases, such as pulmonary arterial hypertension. The present study…

Biological Physics · Physics 2020-01-15 Vasilina Filonova , Hamidreza Gharahi , Nitesh Nama , Seungik Baek , C. Alberto Figueroa

Stress, edge crossings, and crossing angles play an important role in the quality and readability of graph drawings. Most standard graph drawing algorithms optimize one of these criteria which may lead to layouts that are deficient in other…

Computational Geometry · Computer Science 2019-08-26 Sabin Devkota , Reyan Ahmed , Felice De Luca , Katherine E. Isaacs , Stephen Kobourov

The accurate retinal vessel segmentation (RVS) is of great significance to assist doctors in the diagnosis of ophthalmology diseases and other systemic diseases. Manually designing a valid neural network architecture for retinal vessel…

Image and Video Processing · Electrical Eng. & Systems 2020-03-19 Zhun Fan , Jiahong Wei , Guijie Zhu , Jiajie Mo , Wenji Li

We propose a suite of technologies for analyzing the interaction between anisotropic arterial walls and blood flow for subject-specific geometries. Utilizing an established lumen modeling strategy, we present a comprehensive pipeline for…

Medical Physics · Physics 2024-06-21 Yujie Sun , Jiayi Huang , Qingshuang Lu , Xinhai Yue , Xuanming Huang , Wei He , Yun Shi , Ju Liu

The analysis of vessel morphology and connectivity has an impact on a number of cardiovascular and neurovascular applications by providing patient-specific high-level quantitative features such as spatial location, direction and scale. In…

Computer Vision and Pattern Recognition · Computer Science 2018-06-11 Stefano Moriconi , Maria A. Zuluaga , H. Rolf Jäger , Parashkev Nachev , Sébastien Ourselin , M. Jorge Cardoso

In this paper we present a mixed projection- and density-based topology optimization approach. The aim is to combine the benefits of both parametrizations: the explicit geometric representation provides specific controls on certain design…

Computational Engineering, Finance, and Science · Computer Science 2019-10-09 Nicolò Pollini , Oded Amir

Decision trees are widely-used classification and regression models because of their interpretability and good accuracy. Classical methods such as CART are based on greedy approaches but a growing attention has recently been devoted to…

Machine Learning · Computer Science 2021-12-16 Edoardo Amaldi , Antonio Consolo , Andrea Manno

We start with a simple introduction to topological data analysis where the most popular tool is called a persistent diagram. Briefly, a persistent diagram is a multiset of points in the plane describing the persistence of topological…

Statistics Theory · Mathematics 2017-06-28 Christophe Biscio , Jesper Møller

We apply information-based complexity analysis to support vector machine (SVM) algorithms, with the goal of a comprehensive continuous algorithmic analysis of such algorithms. This involves complexity measures in which some higher order…

Machine Learning · Statistics 2012-12-20 Mark A. Kon

An algorithm is developed for finding a close to optimal junction tree of a given graph G. The algorithm has a worst case complexity O(c^k n^a) where a and c are constants, n is the number of vertices, and k is the size of the largest…

Data Structures and Algorithms · Computer Science 2013-02-18 Ann Becker , Dan Geiger

Decompositions of networks are useful not only for structural exploration. They also have implications and use in analysis and computational solution of processes (such as the Ising model, percolation, SIR model) running on a given network.…

Disordered Systems and Neural Networks · Physics 2020-04-29 Konstantin Klemm

The study of the retinal vasculature is a fundamental stage in the screening and diagnosis of many diseases. A complete retinal vascular analysis requires to segment and classify the blood vessels of the retina into arteries and veins…

Image and Video Processing · Electrical Eng. & Systems 2022-09-21 José Morano , Álvaro S. Hervella , Jorge Novo , José Rouco

We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular.…

Fluid Dynamics · Physics 2008-11-11 Renat A. Sultanov , Dennis Guster

The mechanical integrity of arteries is of prime importance, for a proper oxygen and nutrients delivery to all organs. To optimize their mechanical properties, healthy arteries exhibit a complex hierarchical microstructure which ensures a…

Medical Physics · Physics 2019-12-13 Claire Morin , Witold Krasny , Stéphane Avril

An analogy between the fractal nature of networks of arteries and that of systems of rivers has been drawn in the previous works. However, the deep structure of the hierarchy of blood vessels has not yet been revealed. This paper is devoted…

Physics and Society · Physics 2018-12-19 Yanguang Chen

Cerebrovascular diseases such as brain aneurysms are a primary cause of adult disability. The flow dynamics in brain arteries, both during periods of rest and increased activity, are known to be a major factor in the risk of aneurysm…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-04-30 Mohamed A. Itani , Ulf D. Schiller , Sebastian Schmieschek , James Hetherington , Miguel O. Bernabeu , Hoskote Chandrashekar , Fergus Robertson , Peter V. Coveney , Derek Groen

Probabilistic graphical models offer a powerful framework to account for the dependence structure between variables, which is represented as a graph. However, the dependence between variables may render inference tasks intractable. In this…

Knowing a biomolecule's structure is inherently linked to and a prerequisite for any detailed understanding of its function. Significant effort has gone into developing technologies for structural characterization. These technologies do not…

Data Structures and Algorithms · Computer Science 2017-06-22 Michael Wegner , Oskar Taubert , Alexander Schug , Henning Meyerhenke