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We investigate whether generating synthetic data can be a viable strategy for providing access to detailed geocoding information for external researchers, without compromising the confidentiality of the units included in the database. Our…

Applications · Statistics 2020-08-25 Joerg Drechsler , Jingchen Hu

Motivation: Bulk RNA-Seq is a widely used method for studying gene expression across a variety of contexts. The significance of RNA-Seq studies has grown with the advent of high-throughput sequencing technologies. Computational methods have…

Genomics · Quantitative Biology 2025-03-28 Juliana Costa-Silva , David Menotti , Fabricio M. Lopes

Synthetic data generation is one approach for sharing individual-level data. However, to meet legislative requirements, it is necessary to demonstrate that the individuals' privacy is adequately protected. There is no consolidated standard…

Smart vehicles produce large amounts of data, much of which is sensitive and at risk of privacy breaches. As attackers increasingly exploit anonymised metadata within these datasets to profile drivers, it's important to find solutions that…

Cryptography and Security · Computer Science 2024-10-14 Krish Parikh

This paper proposes a general multiple imputation approach for analyzing large-scale data with missing values. An imputation model is derived from a joint distribution induced by a latent variable model, which can flexibly capture…

Methodology · Statistics 2025-09-26 Siliang Zhang , Yunxiao Chen , Jouni Kuha

Most practical data science problems encounter missing data. A wide variety of solutions exist, each with strengths and weaknesses that depend upon the missingness-generating process. Here we develop a theoretical framework for training and…

Machine Learning · Computer Science 2022-11-15 Jahan C. Penny-Dimri , Christoph Bergmeir , Julian Smith

Synthetic datasets are important for evaluating and testing machine learning models. When evaluating real-life recommender systems, high-dimensional categorical (and sparse) datasets are often considered. Unfortunately, there are not many…

Information Retrieval · Computer Science 2024-12-11 Miha Malenšek , Blaž Škrlj , Blaž Mramor , Jure Demšar

Imputing missing values is common practice in label-free quantitative proteomics. Imputation aims at replacing a missing value with a user-defined one. However, the imputation itself may not be optimally considered downstream of the…

Methodology · Statistics 2022-09-08 Marie Chion , Christine Carapito , Frédéric Bertrand

International comparisons of hierarchical time series data sets based on survey data, such as annual country-level estimates of school enrollment rates, can suffer from large amounts of missing data due to differing coverage of surveys…

Methodology · Statistics 2025-03-31 Daphne H. Liu , Adrian E. Raftery

Synthetic data generation has been widely adopted in software testing, data privacy, imbalanced learning, and artificial intelligence explanation. In all such contexts, it is crucial to generate plausible data samples. A common assumption…

Artificial Intelligence · Computer Science 2024-10-16 Martina Cinquini , Fosca Giannotti , Riccardo Guidotti

Multiple imputation has become one of the standard methods in drawing inferences in many incomplete data applications. Applications of multiple imputation in relatively more complex settings, such as high-dimensional clustered data, require…

Methodology · Statistics 2025-04-08 Qiushuang Li , Recai Yucel

Privacy-preserving synthetic data offers a promising solution to harness segregated data in high-stakes domains where information is compartmentalized for regulatory, privacy, or institutional reasons. This survey provides a comprehensive…

Cryptography and Security · Computer Science 2025-03-28 Viktor Schlegel , Anil A Bharath , Zilong Zhao , Kevin Yee

Access to genomic data is highly regulated due to its sensitive nature. While safeguards are essential, cumbersome data access processes pose a significant barrier to the development of AI methods for genomics. Synthetic data generation can…

Cryptography and Security · Computer Science 2026-05-01 Daniil Filienko , Martine De Cock , Sikha Pentyala

Missing values are a major challenge in most data science projects working on real data. To avoid losing valuable information, imputation methods are used to fill in missing values with estimates, allowing the preservation of samples or…

Machine Learning · Computer Science 2024-07-17 Pedro Pons-Suñer , Laura Arnal , J. Ramón Navarro-Cerdán , François Signol

Nested data structures arise when observations are grouped into distinct units, such as patients within hospitals or students within schools. Accounting for this hierarchical organization is essential for valid inference, as ignoring it can…

Computation · Statistics 2025-08-14 Francesco Denti , Laura D'Angelo

Can humans impute missing data with similar proficiency as machines? This is the question we aim to answer in this paper. We present a novel idea of converting observations with missing data in to a survey questionnaire, which is presented…

Machine Learning · Computer Science 2018-02-26 Lovedeep Gondara

Missing data has a ubiquitous presence in real-life applications of machine learning techniques. Imputation methods are algorithms conceived for restoring missing values in the data, based on other entries in the database. The choice of the…

Machine Learning · Computer Science 2017-08-16 Unai Garciarena , Roberto Santana , Alexander Mendiburu

When synthetic data is released, some individuals are harder to protect than others. A patient with a rare disease combination or a transaction with unusual characteristics stands out from the crowd. Differential privacy provides worst-case…

Machine Learning · Computer Science 2026-02-12 Amir Asiaee , Chao Yan , Zachary B. Abrams , Bradley A. Malin

The generation of synthetic data is an essential tool to study complex systems, allowing for example to test models of these in precisely controlled settings, or to parametrize simulation models when data is missing. This paper focuses on…

Applications · Statistics 2019-11-25 Juste Raimbault

We introduce the R package ContaminatedMixt, conceived to disseminate the use of mixtures of multivariate contaminated normal distributions as a tool for robust clustering and classification under the common assumption of elliptically…

Computation · Statistics 2016-06-14 Antonio Punzo , Angelo Mazza , Paul D. McNicholas
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