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Longitudinal studies are frequently used in medical research and involve collecting repeated measures on individuals over time. Observations from the same individual are invariably correlated and thus an analytic approach that accounts for…

Missing data arises when certain values are not recorded or observed for variables of interest. However, most of the statistical theory assume complete data availability. To address incomplete databases, one approach is to fill the gaps…

A common approach to synthetic data is to sample from a fitted model. We show that under general assumptions, this approach results in a sample with inefficient estimators and whose joint distribution is inconsistent with the true…

Statistics Theory · Mathematics 2026-02-18 Jordan Awan , Zhanrui Cai

This paper introduces a novel iterative method for missing data imputation that sequentially reduces the mutual information between data and the corresponding missingness mask. Inspired by GAN-based approaches that train generators to…

Machine Learning · Statistics 2025-11-26 Jiahao Yu , Qizhen Ying , Leyang Wang , Ziyue Jiang , Song Liu

Retrieval-augmented generation (RAG) systems improve large language model outputs by incorporating external knowledge, enabling more informed and context-aware responses. However, the effectiveness and trustworthiness of these systems…

Computation and Language · Computer Science 2025-08-27 Ilias Driouich , Hongliu Cao , Eoin Thomas

Missing data is a prevalent issue in many applications, including large medical registries such as the Swedish Healthcare Quality Registries, potentially leading to biased or inefficient analyses if not handled properly. Multiple Imputation…

Multiple imputation by chained equations (MICE) has emerged as a popular approach for handling missing data. A central challenge for applying MICE is determining how to incorporate outcome information into covariate imputation models,…

Methodology · Statistics 2019-10-11 Lauren Beesley , Jeremy M G Taylor

Most statistical agencies release randomly selected samples of Census microdata, usually with sample fractions under 10% and with other forms of statistical disclosure control (SDC) applied. An alternative to SDC is data synthesis, which…

Cryptography and Security · Computer Science 2022-07-08 Claire Little , Mark Elliot , Richard Allmendinger

We present an approach to inform decisions about nonresponse follow-up sampling. The basic idea is (i) to create completed samples by imputing nonrespondents' data under various assumptions about the nonresponse mechanisms, (ii) take…

Methodology · Statistics 2022-09-16 Thais Paiva , Jerry Reiter

The literature on differential privacy almost invariably assumes that the data to be analyzed are fully observed. In most practical applications this is an unrealistic assumption. A popular strategy to address this problem is imputation, in…

Databases · Computer Science 2022-07-15 Soumojit Das , Jorg Drechsler , Keith Merrill , Shawn Merrill

Gaussian Mixture models (GMMs) are a powerful tool for clustering, classification and density estimation when clustering structures are embedded in the data. The presence of missing values can largely impact the GMMs estimation process,…

Machine Learning · Statistics 2020-06-05 Alessio Serafini , Thomas Brendan Murphy , Luca Scrucca

Data collected in clinical trials are often composed of multiple types of variables. For example, laboratory measurements and vital signs are longitudinal data of continuous or categorical variables, adverse events may be recurrent events,…

Methodology · Statistics 2023-01-12 Tuo Wang , Rachel Zilinskas , Ying Li , Yongming Qu

Multilevel compositional data are data that are repeatedly measured or clustered within groups and are non-negative and sum to a constant value. These data arise in various settings, such as intensive, longitudinal studies using ecological…

Methodology · Statistics 2025-02-21 Flora Le , Tyman E. Stanford , Dorothea Dumuid , Joshua F. Wiley

The prediction interval is gaining prominence in meta-analysis as it enables the assessment of uncertainties in treatment effects and heterogeneity between studies. However, coverage probabilities of the current standard method for…

Methodology · Statistics 2021-10-18 Kengo Nagashima , Hisashi Noma , Toshi A. Furukawa

Missing data are often dealt with multiple imputation. A crucial part of the multiple imputation process is selecting sensible models to generate plausible values for incomplete data. A method based on posterior predictive checking is…

Computation · Statistics 2026-05-14 Mingyang Cai , Stef van Buuren , Gerko Vink

Prediction models are used to predict an outcome based on input variables. Missing data in input variables often occurs at model development and at prediction time. The missForestPredict R package proposes an adaptation of the missForest…

Methodology · Statistics 2024-07-08 Elena Albu , Shan Gao , Laure Wynants , Ben Van Calster

Multilevel compositional data, such as data sampled over time that are non-negative and sum to a constant value, are common in various fields. However, there is currently no software specifically built to model compositional data in a…

Methodology · Statistics 2025-09-23 Flora Le , Dorothea Dumuid , Tyman E. Stanford , Joshua F. Wiley

Healthcare time series data is vital for monitoring patient activity but often contains noise and missing values due to various reasons such as sensor errors or data interruptions. Imputation, i.e., filling in the missing values, is a…

Machine Learning · Computer Science 2024-12-17 Lien P. Le , Xuan-Hien Nguyen Thi , Thu Nguyen , Michael A. Riegler , Pål Halvorsen , Binh T. Nguyen

Conducting research often involves managing multiple disconnected tools for survey design, data collection, response analysis, and report generation, leading to inefficiencies, increased error risks, and challenges in ensuring…

Computation · Statistics 2025-08-11 Clievins Selva

Unbalanced tabular data sets present significant challenges for predictive modeling and data analysis across a wide range of applications. In many real-world scenarios, such as fraud detection, medical diagnosis, and rare event prediction,…

Machine Learning · Computer Science 2025-07-23 Ivona Krchova , Michael Platzer , Paul Tiwald
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