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We reconsider the evaluation of OOD detection methods for image recognition. Although many studies have been conducted so far to build better OOD detection methods, most of them follow Hendrycks and Gimpel's work for the method of…

Computer Vision and Pattern Recognition · Computer Science 2021-01-08 Engkarat Techapanurak , Takayuki Okatani

Neural networks are known to produce over-confident predictions on input images, even when these images are out-of-distribution (OOD) samples. This limits the applications of neural network models in real-world scenarios, where OOD samples…

Computer Vision and Pattern Recognition · Computer Science 2022-07-19 Ke Fan , Yikai Wang , Qian Yu , Da Li , Yanwei Fu

Out-of-distribution (OOD) detection is vital to safety-critical machine learning applications and has thus been extensively studied, with a plethora of methods developed in the literature. However, the field currently lacks a unified,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-14 Jingkang Yang , Pengyun Wang , Dejian Zou , Zitang Zhou , Kunyuan Ding , Wenxuan Peng , Haoqi Wang , Guangyao Chen , Bo Li , Yiyou Sun , Xuefeng Du , Kaiyang Zhou , Wayne Zhang , Dan Hendrycks , Yixuan Li , Ziwei Liu

The detection of semantic and covariate out-of-distribution (OOD) examples is a critical yet overlooked challenge in digital pathology (DP). Recently, substantial insight and methods on OOD detection were presented by the ML community, but…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Ji-Hun Oh , Kianoush Falahkheirkhah , Rohit Bhargava

The automatic detection of skin diseases via dermoscopic images can improve the efficiency in diagnosis and help doctors make more accurate judgments. However, conventional skin disease recognition systems may produce high confidence for…

Computer Vision and Pattern Recognition · Computer Science 2023-01-19 Zhongzheng Huang , Tao Wang , Yuanzheng Cai , Lingyu Liang

Out-of-distribution (OOD) detection is a critical task to ensure the reliability and security of machine learning models deployed in real-world applications. Conventional methods for OOD detection that rely on single-modal information,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 K Huang , G Song , Hanwen Su , Jiyan Wang

Out-of-distribution (OoD) detection for data-based programs is a goal of paramount importance. Common approaches in the literature tend to train detectors requiring inside-of-distribution (in-distribution, or IoD) and OoD validation…

Computer Vision and Pattern Recognition · Computer Science 2023-02-22 Romain Xu-Darme , Julien Girard-Satabin , Darryl Hond , Gabriele Incorvaia , Zakaria Chihani

Recent advances in medical vision-language models (VLMs) demonstrate impressive performance in image classification tasks, driven by their strong zero-shot generalization capabilities. However, given the high variability and complexity…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Lie Ju , Sijin Zhou , Yukun Zhou , Huimin Lu , Zhuoting Zhu , Pearse A. Keane , Zongyuan Ge

Biomedical segmentation networks easily suffer from the unexpected misclassification between foreground and background objects when learning on limited and imperfect medical datasets. Inspired by the strong power of Out-of-Distribution…

Computer Vision and Pattern Recognition · Computer Science 2025-07-17 Yiquan Gao , Duohui Xu

Predictive machine learning models generally excel on in-distribution data, but their performance degrades on out-of-distribution (OOD) inputs. Reliable deployment therefore requires robust OOD detection, yet this is particularly…

Machine Learning · Computer Science 2026-02-19 David Graber , Victor Armegioiu , Rebecca Buller , Siddhartha Mishra

In recent years, research on out-of-distribution (OoD) detection for semantic segmentation has mainly focused on road scenes -- a domain with a constrained amount of semantic diversity. In this work, we challenge this constraint and extend…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Silvio Galesso , Philipp Schröppel , Hssan Driss , Thomas Brox

Out-of-distribution (OOD) detection is a critical task for ensuring the reliability and safety of deep neural networks in real-world scenarios. Different from most previous OOD detection methods that focus on designing OOD scores or…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Yao Zhu , YueFeng Chen , Chuanlong Xie , Xiaodan Li , Rong Zhang , Hui Xue , Xiang Tian , bolun zheng , Yaowu Chen

The capability of reliably detecting out-of-distribution samples is one of the key factors in deploying a good classifier, as the test distribution always does not match with the training distribution in most real-world applications. In…

Machine Learning · Computer Science 2021-04-05 Dongha Lee , Sehun Yu , Hwanjo Yu

It is crucial to detect when an instance lies downright too far from the training samples for the machine learning model to be trusted, a challenge known as out-of-distribution (OOD) detection. For neural networks, one approach to this task…

Out-of-distribution (OOD) detection is crucial when deploying deep neural networks in the real world to ensure the reliability and safety of their applications. One main challenge in OOD detection is that neural network models often produce…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Jinlun Ye , Zhuohao Sun , Yiqiao Qiu , Qiu Li , Zhijun Tan , Ruixuan Wang

Multispectral optical imaging is becoming a key tool in the operating room. Recent research has shown that machine learning algorithms can be used to convert pixel-wise reflectance measurements to tissue parameters, such as oxygenation.…

Image and Video Processing · Electrical Eng. & Systems 2019-11-06 Tim J. Adler , Leonardo Ayala , Lynton Ardizzone , Hannes G. Kenngott , Anant Vemuri , Beat P. Müller-Stich , Carsten Rother , Ullrich Köthe , Lena Maier-Hein

Deep neural networks suffer from the overconfidence issue in the open world, meaning that classifiers could yield confident, incorrect predictions for out-of-distribution (OOD) samples. Thus, it is an urgent and challenging task to detect…

Computer Vision and Pattern Recognition · Computer Science 2022-04-12 Qiuyu Zhu , Guohui Zheng , Yingying Yan

Clinically deployed segmentation models are known to fail on data outside of their training distribution. As these models perform well on most cases, it is imperative to detect out-of-distribution (OOD) images at inference to protect…

Machine Learning · Computer Science 2023-10-23 McKell Woodland , Nihil Patel , Mais Al Taie , Joshua P. Yung , Tucker J. Netherton , Ankit B. Patel , Kristy K. Brock

Out-of-distribution (OOD) detection is crucial for safely deploying automated medical image analysis systems, as abnormal patterns in images could hamper their performance. However, OOD detection in medical imaging remains an open…

Image and Video Processing · Electrical Eng. & Systems 2025-09-18 Evi M. C. Huijben , Sina Amirrajab , Josien P. W. Pluim

Reliable out-of-distribution (OOD) detection is important for safe deployment of deep learning models in fetal ultrasound amidst heterogeneous image characteristics and clinical settings. OOD detection relies on estimating a classification…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Chun Kit Wong , Anders N. Christensen , Cosmin I. Bercea , Julia A. Schnabel , Martin G. Tolsgaard , Aasa Feragen