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The recent achievements of Deep Learning rely on the test data being similar in distribution to the training data. In an ideal case, Deep Learning models would achieve Out-of-Distribution (OoD) Generalization, i.e. reliably make predictions…

Image and Video Processing · Electrical Eng. & Systems 2021-09-07 Antoine Sanner , Camila Gonzalez , Anirban Mukhopadhyay

Detecting out-of-distribution (OOD) samples for trusted medical image segmentation remains a significant challenge. The critical issue here is the lack of a strict definition of abnormal data, which often results in artificial problem…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Anton Vasiliuk , Daria Frolova , Mikhail Belyaev , Boris Shirokikh

Convolutional Neural Networks (CNNs) have shown to be powerful medical image segmentation models. In this study, we address some of the main unresolved issues regarding these models. Specifically, training of these models on small medical…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Davood Karimi , Ali Gholipour

Despite their success, Machine Learning (ML) models do not generalize effectively to data not originating from the training distribution. To reliably employ ML models in real-world healthcare systems and avoid inaccurate predictions on…

Machine Learning · Computer Science 2023-09-29 Mohammad Azizmalayeri , Ameen Abu-Hanna , Giovanni Ciná

This paper presents a principled approach for detecting out-of-distribution (OOD) samples in deep neural networks (DNN). Modeling probability distributions on deep features has recently emerged as an effective, yet computationally cheap…

Machine Learning · Computer Science 2020-12-09 Ibrahima Ndiour , Nilesh Ahuja , Omesh Tickoo

The complex and dynamic real-world clinical environment demands reliable deep learning (DL) systems. Out-of-distribution (OOD) detection plays a critical role in enhancing the reliability and generalizability of DL models when encountering…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Jiangbei Yue , Darren Treanor , Venkataraman Subramanian , Sharib Ali

Out-of-distribution (OOD) detection aims to identify test examples that do not belong to the training distribution and are thus unlikely to be predicted reliably. Despite a plethora of existing works, most of them focused only on the…

Machine Learning · Computer Science 2023-11-07 Reza Averly , Wei-Lun Chao

Reinforcement Learning (RL) based solutions are being adopted in a variety of domains including robotics, health care and industrial automation. Most focus is given to when these solutions work well, but they fail when presented with out of…

Machine Learning · Computer Science 2021-12-07 Aaqib Parvez Mohammed , Matias Valdenegro-Toro

Deep learning has shown to have great potential in medical applications. In critical domains as such, it is of high interest to have trustworthy algorithms which are able to tell when reliable assessments cannot be guaranteed. Detecting…

Computer Vision and Pattern Recognition · Computer Science 2024-03-01 Jennie Karlsson , Marisa Wodrich , Niels Christian Overgaard , Freja Sahlin , Kristina Lång , Anders Heyden , Ida Arvidsson

Out-of-distribution (OOD) detection is crucial for the safety and reliability of artificial intelligence algorithms, especially in the medical domain. In the context of the Medical OOD (MOOD) detection challenge 2023, we propose a pipeline…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Evi M. C. Huijben , Sina Amirrajab , Josien P. W. Pluim

Prior research on out-of-distribution detection (OoDD) has primarily focused on single-modality models. Recently, with the advent of large-scale pretrained vision-language models such as CLIP, OoDD methods utilizing such multi-modal…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Jeonghyeon Kim , Sangheum Hwang

Machine learning methods must be trusted to make appropriate decisions in real-world environments, even when faced with out-of-distribution (OOD) samples. Many current approaches simply aim to detect OOD examples and alert the user when an…

Machine Learning · Computer Science 2022-09-13 Randolph Linderman , Jingyang Zhang , Nathan Inkawhich , Hai Li , Yiran Chen

Detecting test-time distribution shift has emerged as a key capability for safely deployed machine learning models, with the question being tackled under various guises in recent years. In this paper, we aim to provide a consolidated view…

Computer Vision and Pattern Recognition · Computer Science 2024-09-02 Hongjun Wang , Sagar Vaze , Kai Han

Out-of-distribution (OOD) detection is a task that detects OOD samples during inference to ensure the safety of deployed models. However, conventional benchmarks have reached performance saturation, making it difficult to compare recent OOD…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Shiho Noda , Atsuyuki Miyai , Qing Yu , Go Irie , Kiyoharu Aizawa

We present a principled approach for detecting out-of-distribution (OOD) and adversarial samples in deep neural networks. Our approach consists in modeling the outputs of the various layers (deep features) with parametric probability…

Machine Learning · Statistics 2019-09-27 Nilesh A. Ahuja , Ibrahima Ndiour , Trushant Kalyanpur , Omesh Tickoo

Deep neural networks are known to achieve superior results in classification tasks. However, it has been recently shown that they are incapable to detect examples that are generated by a distribution which is different than the one they…

Machine Learning · Computer Science 2019-12-09 Aristotelis-Angelos Papadopoulos , Nazim Shaikh , Mohammad Reza Rajati

It is an important problem in trustworthy machine learning to recognize out-of-distribution (OOD) inputs which are inputs unrelated to the in-distribution task. Many out-of-distribution detection methods have been suggested in recent years.…

Machine Learning · Computer Science 2022-06-22 Julian Bitterwolf , Alexander Meinke , Maximilian Augustin , Matthias Hein

Clinical machine learning models show a significant performance drop when tested in settings not seen during training. Domain generalisation models promise to alleviate this problem, however, there is still scepticism about whether they…

Machine Learning · Computer Science 2022-11-14 Dimitris Spathis , Stephanie L. Hyland

Applying machine learning to increasingly high-dimensional problems with sparse or biased training data increases the risk that a model is used on inputs outside its training domain. For such out-of-distribution (OOD) inputs, the model can…

Machine Learning · Computer Science 2025-03-10 Juniper Tyree , Andreas Rupp , Petri S. Clusius , Michael H. Boy

Out-of-distribution detection (OOD) is a pivotal task for real-world applications that trains models to identify samples that are distributionally different from the in-distribution (ID) data during testing. Recent advances in AI,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Chaohua Li , Enhao Zhang , Chuanxing Geng , Songcan Chen