Related papers: Adverse event enrichment tests using VAERS
Over the past decade, deep learning (DL) has been successfully applied to many industrial domain-specific tasks. However, the current state-of-the-art DL software still suffers from quality issues, which raises great concern especially in…
Building on the success of deep learning, two modern approaches to learn a probability model from the data are Generative Adversarial Networks (GANs) and Variational AutoEncoders (VAEs). VAEs consider an explicit probability model for the…
Drug Names, Population Level Surveillance and the FDA's Adverse Event Reporting System: An Exploratory Data Survey of Drug Name Incidence and Prevalence, 2004-2012Q2 Purpose: To count and monitor the drug names reported in the publicly…
Deep Learning (DL) is increasingly used in safety-critical applications, raising concerns about its reliability. DL suffers from a well-known problem of lacking robustness, especially when faced with adversarial perturbations known as…
Generating accurate extremes from an observational data set is crucial when seeking to estimate risks associated with the occurrence of future extremes which could be larger than those already observed. Applications range from the…
Poisoning attacks are a category of adversarial machine learning threats in which an adversary attempts to subvert the outcome of the machine learning systems by injecting crafted data into training data set, thus increasing the machine…
The framework of variational autoencoders (VAEs) provides a principled method for jointly learning latent-variable models and corresponding inference models. However, the main drawback of this approach is the blurriness of the generated…
In anomaly detection (AD), one seeks to identify whether a test sample is abnormal, given a data set of normal samples. A recent and promising approach to AD relies on deep generative models, such as variational autoencoders (VAEs), for…
In Federated Learning (FL), anomaly detection (AD) is a challenging task due to the decentralized nature of data and the presence of non-IID data distributions. This study introduces a novel federated threshold calculation method that…
Machine learning with deep neural networks (DNNs) has become one of the foundation techniques in many safety-critical systems, such as autonomous vehicles and medical diagnosis systems. DNN-based systems, however, are known to be vulnerable…
Clinical trials face mounting challenges: fragmented patient populations, slow enrollment, and unsustainable costs, particularly for late phase trials in oncology and rare diseases. While external control arms built from real-world data…
Learning from an imbalanced distribution presents a major challenge in predictive modeling, as it generally leads to a reduction in the performance of standard algorithms. Various approaches exist to address this issue, but many of them…
Adversarial examples (AEs) are images that can mislead deep neural network (DNN) classifiers via introducing slight perturbations into original images. This security vulnerability has led to vast research in recent years because it can…
Electricity distribution cable networks suffer from incomplete and unbalanced data, hindering the effectiveness of machine learning models for predictive maintenance and reliability evaluation. Features such as the installation date of the…
Objective: The objective of this study is to develop a deep learning pipeline to detect signals on dietary supplement-related adverse events (DS AEs) from Twitter. Material and Methods: We obtained 247,807 tweets ranging from 2012 to 2018…
Deep neural networks (DNNs) are well known to be vulnerable to adversarial examples (AEs). In addition, AEs have adversarial transferability, which means AEs generated for a source model can fool another black-box model (target model) with…
Adversarial examples (AEs) pose severe threats to the applications of deep neural networks (DNNs) to safety-critical domains, e.g., autonomous driving. While there has been a vast body of AE defense solutions, to the best of our knowledge,…
Generative Adversarial Networks (GANs) represent a promising class of generative networks that combine neural networks with game theory. From generating realistic images and videos to assisting musical creation, GANs are transforming many…
Adverse drug events (ADEs) are an important aspect of drug safety. Various texts such as biomedical literature, drug reviews, and user posts on social media and medical forums contain a wealth of information about ADEs. Recent studies have…
It is important to detect anomalous inputs when deploying machine learning systems. The use of larger and more complex inputs in deep learning magnifies the difficulty of distinguishing between anomalous and in-distribution examples. At the…