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Magnetic particle imaging (MPI) is a medical imaging modality of recent origin, and it exploits the nonlinear magnetization phenomenon to recover the spatially dependent concentration of the nanoparticles. Currently, image reconstruction in…

Numerical Analysis · Mathematics 2019-04-23 Tobias Kluth , Bangti Jin

Magnetic Particle Imaging (MPI) is a tomographic imaging technique for determining the spatial distribution of superparamagnetic nanoparticles. Current MPI systems are capable of imaging iron masses over a wide dynamic range of more than…

Magnetic particle imaging (MPI) offers unparalleled contrast and resolution for tracing magnetic nanoparticles. A common imaging procedure calibrates a system matrix (SM) that is used to reconstruct data from subsequent scans. The ill-posed…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Alper Güngör , Baris Askin , Damla Alptekin Soydan , Can Barış Top , Emine Ulku Saritas , Tolga Çukur

Magnetic particle imaging (MPI) is a relatively new imaging modality. The nonlinear magnetization behavior of nanoparticles in an applied magnetic field is employed to reconstruct an image of the concentration of nanoparticles. Finding a…

Applied Physics · Physics 2018-07-04 Tobias Kluth

Magnetic Particle Imaging (MPI) is a promising tracer-based, functional medical imaging technique which measures the non-linear magnetization response of magnetic nanoparticles to a dynamic magnetic field. For image reconstruction, system…

Image and Video Processing · Electrical Eng. & Systems 2021-08-26 Christina Brandt , Christiane Schmidt

Magnetic Particle Imaging (MPI) is a recent imaging modality where superparamagnetic nanoparticles are employed as tracers. The reconstruction task is to obtain the spatial particle distribution from a voltage signal induced by the…

Numerical Analysis · Mathematics 2025-08-11 Thomas März , Vladyslav Gapyak , Andreas Weinmann

Magnetic particle imaging (MPI) is an imaging method that can visualize magnetic nanoparticles in positive contrast, without radiation exposure. Recently, we proposed an image reconstruction method for projection-based MPI (pMPI), in which…

Medical Physics · Physics 2023-05-01 Kenya Murase

The image reconstruction problem of the tomographic imaging technique magnetic particle imaging (MPI) requires the solution of a linear inverse problem. One prerequisite for this task is that the imaging operator that describes the mapping…

Computational Physics · Physics 2019-07-12 Tobias Kluth , Patryk Szwargulski , Tobias Knopp

Magnetic Particle Imaging (MPI) is a novel medical imaging modality. One of the established methods for MPI reconstruction is based on the System Matrix (SM). However, the calibration of the SM is often time-consuming and requires repeated…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Xuqing Geng , Lei Su , Zhongwei Bian , Zewen Sun , Jiaxuan Wen , Jie Tian , Yang Du

Magnetic Particle Imaging (MPI) is a preclinical imaging technique capable of visualizing the spatio-temporal distribution of magnetic nanoparticles. The image reconstruction of this fast and dynamic process relies on efficiently solving an…

Numerical Analysis · Mathematics 2021-09-15 Florian Lieb , Tobias Knopp

Magnetic particle imaging (MPI) is a non-invasive, non-ionizing imaging technique for the visualization and quantification of magnetic nanoparticles (MNPs). The technique is especially suitable for cell imaging as it offers zero background…

Various imaging modalities allow for time-dependent image reconstructions from measurements where its acquisition also has a time-dependent nature. Magnetic particle imaging (MPI) falls into this class of imaging modalities and it thus also…

Numerical Analysis · Mathematics 2023-06-21 Christina Brandt , Tobias Kluth , Tobias Knopp , Lena Westen

Magnetic Particle Imaging (MPI) is an emerging imaging modality based on the magnetic response of superparamagnetic iron oxide nanoparticles to achieve high-resolution and real-time imaging without harmful radiation. One key challenge in…

Numerical Analysis · Mathematics 2025-01-13 Meira Iske , Hannes Albers , Tobias Knopp , Tobias Kluth

Magnetic particle imaging (MPI) is an emerging medical imaging modality which offers a unique combination of high temporal and spatial resolution, sensitivity and biocompatibility. For system-matrix (SM) based image reconstruction in MPI, a…

Software Engineering · Computer Science 2024-01-12 Anselm von Gladiss , Amir Shayan Ahmadian , Jan Jürjens

We contribute to the mathematical modeling and analysis of magnetic particle imaging which is a promising new in-vivo imaging modality. Concerning modeling, we develop a structured decomposition of the imaging process and extract its core…

Numerical Analysis · Mathematics 2016-05-27 Thomas März , Andreas Weinmann

Magnetic resonance imaging (MRI) reconstruction is a fundamental task aimed at recovering high-quality images from undersampled or low-quality MRI data. This process enhances diagnostic accuracy and optimizes clinical applications. In…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Xiaoyan Kui , Zijie Fan , Zexin Ji , Qinsong Li , Chengtao Liu , Weixin Si , Beiji Zou

Reconstructing magnetization in nanoscale magnetic thin films is essential for developing next-generation memory, sensors, and various spintronic technologies. However, this remains challenging due to the ill-posed nature of the stray field…

Disordered Systems and Neural Networks · Physics 2026-04-28 Zander Scholl , Justin Woods , Charudatta Phatak , Hanu Arava

Magnetic particle imaging (MPI) is a tracer-based imaging modality that detects superparamagnetic iron oxide nanoparticles in vivo, with applications in cancer cell tracking, lymph node mapping, and cell therapy monitoring. We introduce a…

Objective: Magnetic particle imaging (MPI) is an emerging medical imaging modality which has gained increasing interest in recent years. Among the benefits of MPI are its high temporal resolution, and that the technique does not expose the…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Vladyslav Gapyak , Corinna Rentschler , Thomas März , Andreas Weinmann

In Magnetic Particle Imaging (MPI), it is typically assumed that the studied specimen is stationary during the data acquisition. In practical applications however, the searched-for 3D distribution of the magnetic nanoparticles might show a…

Optimization and Control · Mathematics 2024-01-26 Marius Nitzsche , Bernadette N Hahn
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