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The remarkable achievements of Artificial Intelligence (AI) algorithms, particularly in Machine Learning (ML) and Deep Learning (DL), have fueled their extensive deployment across multiple sectors, including Software Engineering (SE).…

Software Engineering · Computer Science 2025-02-06 Sicong Cao , Xiaobing Sun , Ratnadira Widyasari , David Lo , Xiaoxue Wu , Lili Bo , Jiale Zhang , Bin Li , Wei Liu , Di Wu , Yixin Chen

Artificial intelligence now outperforms humans in several scientific and engineering tasks, yet its internal representations often remain opaque. In this Perspective, we argue that explainable artificial intelligence (XAI), combined with…

Artificial Intelligence · Computer Science 2026-02-17 Ricardo Vinuesa , Steven L. Brunton , Gianmarco Mengaldo

In recent years, deep learning has achieved unprecedented success in various computer vision tasks, particularly in object detection. However, the black-box nature and high complexity of deep neural networks pose significant challenges for…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 FatemehSadat Seyedmomeni , Mohammad Ali Keyvanrad

Mechanistic interpretability aims to understand the computational mechanisms underlying neural networks' capabilities in order to accomplish concrete scientific and engineering goals. Progress in this field thus promises to provide greater…

Drug discovery remains a slow and expensive process that involves many steps, from detecting the target structure to obtaining approval from the Food and Drug Administration (FDA), and is often riddled with safety concerns. Accurate…

Quantitative Methods · Quantitative Biology 2025-08-22 Ali Vefghi , Zahed Rahmati , Mohammad Akbari

Nowadays, deep neural networks are widely used in mission critical systems such as healthcare, self-driving vehicles, and military which have direct impact on human lives. However, the black-box nature of deep neural networks challenges its…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Arun Das , Paul Rad

Artificial Intelligence models are becoming increasingly more powerful and accurate, supporting or even replacing humans' decision making. But with increased power and accuracy also comes higher complexity, making it hard for users to…

Artificial Intelligence · Computer Science 2019-07-10 Vivian S. Silva , André Freitas , Siegfried Handschuh

Medical toxicology is the clinical specialty that treats the toxic effects of substances, be it an overdose, a medication error, or a scorpion sting. The volume of toxicological knowledge and research has, as with other medical specialties,…

Artificial Intelligence · Computer Science 2021-02-03 Michael Chary , Ed W Boyer , Michele M Burns

Recent applications of machine learning and statistical inference provide case studies demonstrating how such approaches can accelerate the discovery process in physical chemistry and related fields. Examples discussed in this review…

Chemical Physics · Physics 2017-06-20 Ryan B. Jadrich , Beth A. Lindquist , Thomas M. Truskett

Scientific discovery is a complex cognitive process that has driven human knowledge and technological progress for centuries. While artificial intelligence (AI) has made significant advances in automating aspects of scientific reasoning,…

Machine Learning · Computer Science 2024-12-24 Chandan K Reddy , Parshin Shojaee

Despite significant advancements in XAI, scholars note a persistent lack of solid conceptual foundations and integration with broader scientific discourse on explanation. In response, emerging research draws on explanatory strategies from…

Machine Learning · Computer Science 2026-05-22 Marcin Rabiza

The scientific community has been increasingly interested in harnessing the power of deep learning to solve various domain challenges. However, despite the effectiveness in building predictive models, fundamental challenges exist in…

Machine Learning · Computer Science 2020-07-20 Shusen Liu , Bhavya Kailkhura , Jize Zhang , Anna M. Hiszpanski , Emily Robertson , Donald Loveland , T. Yong-Jin Han

Deep visual models have widespread applications in high-stake domains. Hence, their black-box nature is currently attracting a large interest of the research community. We present the first survey in Explainable AI that focuses on the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Naveed Akhtar

Predictions obtained by, e.g., artificial neural networks have a high accuracy but humans often perceive the models as black boxes. Insights about the decision making are mostly opaque for humans. Particularly understanding the decision…

Machine Learning · Computer Science 2021-01-21 Nadia Burkart , Marco F. Huber

The recent surge in Generative Artificial Intelligence (AI) has introduced exciting possibilities for computational chemistry. Generative AI methods have made significant progress in sampling molecular structures across chemical species,…

Statistical Mechanics · Physics 2024-09-06 Pratyush Tiwary , Lukas Herron , Richard John , Suemin Lee , Disha Sanwal , Ruiyu Wang

Recently supervised machine learning has been ascending in providing new predictive approaches for chemical, biological and materials sciences applications. In this Perspective we focus on the interplay of machine learning algorithm with…

The rapid evolution of machine learning (ML) has led to the widespread adoption of complex "black box" models, such as deep neural networks and ensemble methods. These models exhibit exceptional predictive performance, making them…

Machine Learning · Computer Science 2025-03-28 Moncef Garouani , Josiane Mothe , Ayah Barhrhouj , Julien Aligon

Artificial Intelligence in Medicine has made significant progress with emerging applications in medical imaging, patient care, and other areas. While these applications have proven successful in retrospective studies, very few of them were…

Artificial Intelligence · Computer Science 2023-08-11 Nicoletta Prentzas , Antonis Kakas , Constantinos S. Pattichis

Explainability techniques for data-driven predictive models based on artificial intelligence and machine learning algorithms allow us to better understand the operation of such systems and help to hold them accountable. New transparency…

Machine Learning · Computer Science 2022-09-09 Kacper Sokol , Alexander Hepburn , Raul Santos-Rodriguez , Peter Flach

Artificial intelligence-augmented technology represents a considerable opportunity for improving healthcare delivery. Significant progress has been made to demonstrate the value of complex models to enhance clinicians` efficiency in…

Human-Computer Interaction · Computer Science 2025-04-08 Mohammad Golam Kibria , Lauren Kucirka , Javed Mostafa