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We study the problem of sampling a uniformly random directed rooted spanning tree, also known as an arborescence, from a possibly weighted directed graph. Classically, this problem has long been known to be polynomial-time solvable; the…

Data Structures and Algorithms · Computer Science 2020-12-18 Nima Anari , Nathan Hu , Amin Saberi , Aaron Schild

It was recently observed by de Vienne et al. that a simple square root transformation of distances between taxa on a phylogenetic tree allowed for an embedding of the taxa into Euclidean space. While the justification for this was based on…

Populations and Evolution · Quantitative Biology 2016-05-04 Mark Layer , John A. Rhodes

Phylogenetic trees elucidate evolutionary relationships among species, but phylogenetic inference remains challenging due to the complexity of combining continuous (branch lengths) and discrete parameters (tree topology). Traditional Markov…

Populations and Evolution · Quantitative Biology 2024-12-30 ChenRui Duan , Zelin Zang , Siyuan Li , Yongjie Xu , Stan Z. Li

Phylogenetic networks are a generalisation of phylogenetic trees that allow for more complex evolutionary histories that include hybridisation-like processes. It is of considerable interest whether a network can be considered `tree-like' or…

Populations and Evolution · Quantitative Biology 2017-11-21 Michael Hendriksen

Tree containment problem is a fundamental problem in phylogenetic study, as it is used to verify a network model. It asks whether a given network contain a subtree that resembles a binary tree. The problem is NP-complete in general, even in…

Populations and Evolution · Quantitative Biology 2017-02-15 Andreas Gunawan

A contemporary and fundamental problem faced by many evolutionary biologists is how to puzzle together a collection $\mathcal P$ of partial trees (leaf-labelled trees whose leaves are bijectively labelled by species or, more generally,…

Combinatorics · Mathematics 2007-09-04 S. Grünewald , K. T. Huber , Q. Wu

'Tree-based' phylogenetic networks proposed by Francis and Steel have attracted much attention of theoretical biologists in the last few years. At the heart of the definitions of tree-based phylogenetic networks is the notion of 'support…

Combinatorics · Mathematics 2019-04-30 Momoko Hayamizu , Kazuhisa Makino

The enumeration of chemical graphs is an important topic in cheminformatics and bioinformatics, particularly in the discovery of novel drugs. These graphs are typically either tree-like multigraphs or composed of tree-like multigraphs…

Discrete Mathematics · Computer Science 2025-02-11 Muhammad Ilyas , Seemab Hayat , Naveed Ahmed Azam

Recent work has proven the existence of extreme inbreeding in a European ancestry sample taken from the contemporary UK population \cite{nature_01}. This result brings our attention again to a math problem related to inbreeding family trees…

Populations and Evolution · Quantitative Biology 2021-09-08 C. Jarne , F A. Gómez Albarracín , M. Caruso

Among the distance based algorithms in phylogenetic tree reconstruction, the neighbor-joining algorithm has been a widely used and effective method. We propose a new algorithm which counts the number of consistent quartets for cherry…

Populations and Evolution · Quantitative Biology 2023-10-31 Jin-Hwan Cho , Dosang Joe , Young Rock Kim

We study the natural problem of Triplet Reconstruction (also Rooted Triplets Consistency or Triplet Clustering), originally motivated in computational biology and relational databases (Aho, Sagiv, Szymanski, and Ullman, 1981): given $n$…

Data Structures and Algorithms · Computer Science 2023-04-06 Vaggos Chatziafratis , Konstantin Makarychev

In this paper we consider the following modification of the iterative search problem. We are given a tree $T$, so that a dynamic catalog $C(v)$ is associated with every tree node $v$. For any $x$ and for any node-to-root path $\pi$ in $T$,…

Data Structures and Algorithms · Computer Science 2010-07-21 Yakov Nekrich

In this paper we introduce and study three new measures for efficient discriminative comparison of phylogenetic trees. The NNI navigation dissimilarity $d_{nav}$ counts the steps along a "combing" of the Nearest Neighbor Interchange (NNI)…

Populations and Evolution · Quantitative Biology 2015-10-21 Omur Arslan , Dan P. Guralnik , Daniel E. Koditschek

Min-Cut queries are fundamental: Preprocess an undirected edge-weighted graph, to quickly report a minimum-weight cut that separates a query pair of nodes $s,t$. The best data structure known for this problem simply builds a cut-equivalent…

Data Structures and Algorithms · Computer Science 2020-09-15 Amir Abboud , Robert Krauthgamer , Ohad Trabelsi

Distance-based phylogenetic algorithms attempt to solve the NP-hard least squares phylogeny problem by mapping an arbitrary dissimilarity map representing biological data to a tree metric. The set of all dissimilarity maps is a Euclidean…

Populations and Evolution · Quantitative Biology 2013-07-24 Ruth Davidson , Seth Sullivant

Reproducibility is a crucial aspect of scientific research that involves the ability to independently replicate experimental results by analysing the same data or repeating the same experiment. Over the years, many works have been proposed…

Digital Libraries · Computer Science 2024-07-16 Andrea Bianchi , Giordano d'Aloisio , Francesca Marzi , Antinisca Di Marco

A chief problem in phylogenetics and database theory is the computation of a maximum consistent tree from a set of rooted or unrooted trees. A standard input are triplets, rooted binary trees on three leaves, or quartets, unrooted binary…

Discrete Mathematics · Computer Science 2010-05-31 Leo van Iersel , Matthias Mnich

Pedigree graphs, or family trees, are typically constructed by an expensive process of examining genealogical records to determine which pairs of individuals are parent and child. New methods to automate this process take as input genetic…

Data Structures and Algorithms · Computer Science 2011-10-19 Bonnie Kirkpatrick , Yakir Reshef , Hilary Finucane , Haitao Jiang , Binhai Zhu , Richard M. Karp

We consider the problem of recovering items matching a partially specified pattern in multidimensional trees (quad trees and k-d trees). We assume the traditional model where the data consist of independent and uniform points in the unit…

Probability · Mathematics 2011-07-13 Nicolas Broutin , Ralph Neininger , Henning Sulzbach

Trees can accelerate queries that search or aggregate values over large collections. They achieve this by storing metadata that enables quick pruning (or inclusion) of subtrees when predicates on that metadata can prove that none (or all)…