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The use of machine learning algorithms in finance, medicine, and criminal justice can deeply impact human lives. As a consequence, research into interpretable machine learning has rapidly grown in an attempt to better control and fix…

Machine Learning · Computer Science 2021-02-02 Thibaut Vidal , Toni Pacheco , Maximilian Schiffer

Phylogenetic trees in genetics and biology in general are all binary. We make an attempt to answer one fundamental question: Is such binary branching from the coarsest to the finest scales sustained by data? We convert this question into an…

Methodology · Statistics 2018-01-29 Tania Roy , Hsieh Fushing , Xunde Li , Brenda McCowan , Rob Atwill

When gene copies are sampled from various species, the resulting gene tree might disagree with the containing species tree. The primary causes of gene tree and species tree discord include lineage sorting, horizontal gene transfer, and gene…

Populations and Evolution · Quantitative Biology 2010-03-08 Louxin Zhang

Despite the latest prevailing success of deep neural networks (DNNs), several concerns have been raised against their usage, including the lack of intepretability the gap between DNNs and other well-established machine learning models, and…

Machine Learning · Computer Science 2021-01-01 Jianghao Shen , Sicheng Wang , Zhangyang Wang

Full binary trees naturally represent commutative non-associative products. There are many important examples of these products: finite-precision floating-point addition and NAND gates, among others. Balance in such a tree is highly…

Discrete Mathematics · Computer Science 2021-08-27 Laura Monroe

We present a simple $O(n^4)$-time algorithm for computing optimal search trees with two-way comparisons. The only previous solution to this problem, by Anderson et al., has the same running time, but is significantly more complicated and is…

Data Structures and Algorithms · Computer Science 2022-02-14 Marek Chrobak , Mordecai Golin , J. Ian Munro , Neal E. Young

Balanced search trees are widely used in computer science to efficiently maintain dynamic ordered data. To support efficient set operations (e.g., union, intersection, difference) using trees, the join-based framework is widely studied.…

Data Structures and Algorithms · Computer Science 2025-10-24 Michael Goodrich , Yan Gu , Ryuto Kitagawa , Yihan Sun

Modelling the substitution of nucleotides along a phylogenetic tree is usually done by a hidden Markov process. This allows to define a distribution of characters at the leaves of the trees and one might be able to obtain polynomial…

Populations and Evolution · Quantitative Biology 2020-10-12 Marta Casanellas , Jesús Fernández-Sánchez , Marina Garrote-López

As researchers collect increasingly large molecular data sets to reconstruct the Tree of Life, the heterogeneity of signals in the genomes of diverse organisms poses challenges for traditional phylogenetic analysis. A class of phylogenetic…

Populations and Evolution · Quantitative Biology 2015-09-11 Liang Liu , Zhenxiang Xi , Shaoyuan Wu , Charles Davis , Scott V. Edwards

A decision tree recursively splits a feature space $\mathbb{R}^{d}$ and then assigns class labels based on the resulting partition. Decision trees have been part of the basic machine-learning toolkit for decades. A large body of work treats…

The history of gene families - which are equivalent to \emph{event-labeled} gene trees - can be reconstructed from empirically estimated evolutionary event-relations containing pairs of orthologous, paralogous or xenologous genes. The…

Discrete Mathematics · Computer Science 2017-06-13 Marc Hellmuth

The block tree [Belazzougui et al., J. Comput. Syst. Sci. '21] is a compressed representation of a length-$n$ text that supports access, rank, and select queries while requiring only $O(z\log\frac{n}{z})$ words of space, where $z$ is the…

Data Structures and Algorithms · Computer Science 2025-12-30 Robert Clausecker , Florian Kurpicz , Etienne Palanga

Understanding the dynamics of genome rearrangements is a major issue of phylogenetics. Phylogenetics is the study of species evolution. A major goal of the field is to establish evolutionary relationships within groups of species, in order…

Data Structures and Algorithms · Computer Science 2014-10-22 Antoine Thomas

In the dynamic tree problem the goal is the maintenance of an arbitrary n-vertex forest, where the trees are subject to joining and splitting by, respectively, adding and removing edges. Depending on the application, information can be…

Data Structures and Algorithms · Computer Science 2015-09-23 Gabriele Farina , Luigi Laura

The multispecies coalescent process models the genealogical relationships of genes sampled from several species, enabling useful predictions about phenomena such as the discordance between the gene tree and the species phylogeny due to…

Populations and Evolution · Quantitative Biology 2020-12-11 Jakub Truszkowski , Celine Scornavacca , Fabio Pardi

Tree-based phylogenetic networks, which may be roughly defined as leaf-labeled networks built by adding arcs only between the original tree edges, have elegant properties for modeling evolutionary histories. We answer an open question of…

In this paper, we investigate the computational complexity of subgraph reconfiguration problems in directed graphs. More specifically, we focus on the problem of reconfiguring arborescences in a digraph, where an arborescence is a directed…

Data Structures and Algorithms · Computer Science 2023-03-16 Takehiro Ito , Yuni Iwamasa , Yasuaki Kobayashi , Yu Nakahata , Yota Otachi , Kunihiro Wasa

Computing $k$-Nearest Neighbors (KNN) is one of the core kernels used in many machine learning, data mining and scientific computing applications. Although kd-tree based $O(\log n)$ algorithms have been proposed for computing KNN, due to…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-17 Md. Mostofa Ali Patwary , Nadathur Rajagopalan Satish , Narayanan Sundaram , Jialin Liu , Peter Sadowski , Evan Racah , Suren Byna , Craig Tull , Wahid Bhimji , Prabhat , Pradeep Dubey

Modern trends in data collection are bringing current mainstream techniques for database query processing to their limits. Consequently, various novel approaches for efficient query processing are being actively studied. One such approach…

Databases · Computer Science 2022-04-13 Georg Gottlob , Matthias Lanzinger , Cem Okulmus , Reinhard Pichler

A phylogenetic variety is an algebraic variety parameterized by a statistical model of the evolution of biological sequences along a tree. Understanding this variety is an important problem in the area of algebraic statistics with…

Populations and Evolution · Quantitative Biology 2024-05-22 Luis David Garcia Puente , Marina Garrote-López , Elima Shehu
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