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The pharmaceutical Research and development (R&D) process is lengthy and costly, taking nearly a decade to bring a new drug to the market. However, advancements in biotechnology, computational methods, and machine learning algorithms have…

Biomolecules · Quantitative Biology 2024-01-24 Damilola Oshunyinka

Applying a ML approach to the temporal variability of the Spike protein sequence enables us to identify, classify and track emerging virus variants. Our analysis is unbiased, in the sense that it does not require any prior knowledge of the…

The recent pandemic has underscored the importance of accurately diagnosing COVID-19 in hospital settings. A major challenge in this regard is differentiating COVID-19 from other respiratory illnesses based on chest X-rays, compounded by…

Image and Video Processing · Electrical Eng. & Systems 2024-01-24 Rittika Adhikari , Christopher Settles

Diagnosis of COVID-19 is necessary to prevent and control the disease. Deep learning methods have been considered a fast and accurate method. In this paper, by the parallel combination of three well-known pre-trained networks, we attempted…

Image and Video Processing · Electrical Eng. & Systems 2022-08-17 Faezeh Amouzegar , Hamid Mirvaziri , Mostafa Ghazizadeh-Ahsaee , Mahdi Shariatzadeh

The SARS-CoV-2 virus and COVID-19 disease have posed unprecedented and overwhelming demand, challenges and opportunities to domain, model and data driven modeling. This paper provides a comprehensive review of the challenges, tasks,…

Computers and Society · Computer Science 2021-08-05 Longbing Cao , Qing Liu

The COVID-19 is sweeping the world with deadly consequences. Its contagious nature and clinical similarity to other pneumonias make separating subjects contracted with COVID-19 and non-COVID-19 viral pneumonia a priority and a challenge.…

Machine Learning · Computer Science 2020-05-15 Forrest Sheng Bao , Youbiao He , Jie Liu , Yuanfang Chen , Qian Li , Christina R. Zhang , Lei Han , Baoli Zhu , Yaorong Ge , Shi Chen , Ming Xu , Liu Ouyang

COVID-19 (Coronavirus disease 2019) has been quickly spreading since its outbreak, impacting financial markets and healthcare systems globally. Countries all around the world have adopted a number of extraordinary steps to restrict the…

Image and Video Processing · Electrical Eng. & Systems 2023-02-16 Song Wu , Yazhou Ren , Aodi Yang , Xinyue Chen , Xiaorong Pu , Jing He , Liqiang Nie , Philip S. Yu

Because of the rapid spread of COVID-19 to almost every part of the globe, huge volumes of data and case studies have been made available, providing researchers with a unique opportunity to find trends and make discoveries like never…

Machine Learning · Computer Science 2021-10-20 Sarwan Ali , Yijing Zhou , Murray Patterson

Emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have compromised existing vaccines and posed a grand challenge to coronavirus disease 2019 (COVID-19) prevention, control, and global economic recovery. For…

Biomolecules · Quantitative Biology 2022-04-21 Jiahui Chen , Guo-Wei Wei

The COVID-19 pandemic triggered a wave of novel scientific literature that is impossible to inspect and study in a reasonable time frame manually. Current machine learning methods offer to project such body of literature into the vector…

Information Retrieval · Computer Science 2021-10-19 Blaž Škrlj , Marko Jukič , Nika Eržen , Senja Pollak , Nada Lavrač

The outbreak of the novel coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been continuously affecting human lives and communities around the world in many ways, from cities…

Machine Learning · Computer Science 2020-07-24 Ashkan Ebadi , Pengcheng Xi , Stéphane Tremblay , Bruce Spencer , Raman Pall , Alexander Wong

Structure-based Deep Fusion models were recently shown to outperform several physics- and machine learning-based protein-ligand binding affinity prediction methods. As part of a multi-institutional COVID-19 pandemic response, over 500…

The SARS-CoV-2 coronavirus is the cause of the COVID-19 disease in humans. Like many coronaviruses, it can adapt to different hosts and evolve into different lineages. It is well-known that the major SARS-CoV-2 lineages are characterized by…

Machine Learning · Computer Science 2022-11-23 Sarwan Ali

As the COVID-19 pandemic continues to devastate globally, one promising field of research is machine learning-driven computer vision to streamline various parts of the COVID-19 clinical workflow. These machine learning methods are typically…

Image and Video Processing · Electrical Eng. & Systems 2021-09-15 Audrey G. Chung , Maya Pavlova , Hayden Gunraj , Naomi Terhljan , Alexander MacLean , Hossein Aboutalebi , Siddharth Surana , Andy Zhao , Saad Abbasi , Alexander Wong

In recent months the world has been surprised by the rapid advance of COVID-19. In order to face this disease and minimize its socio-economic impacts, in addition to surveillance and treatment, diagnosis is a crucial procedure. However, the…

Image and Video Processing · Electrical Eng. & Systems 2020-07-13 Lucas P. Soares , Cesar P. Soares

Until now, Coronavirus SARS-CoV-2 has caused more than 850,000 deaths and infected more than 27 million individuals in over 120 countries. Besides principal polymerase chain reaction (PCR) tests, automatically identifying positive samples…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Duy M. H. Nguyen , Duy M. Nguyen , Huong Vu , Binh T. Nguyen , Fabrizio Nunnari , Daniel Sonntag

For fast development of COVID-19, it is only feasible to use drugs (off label use) or approved natural products that are already registered or been assessed for safety in previous human trials. These agents can be quickly assessed in…

Biomolecules · Quantitative Biology 2020-12-01 Sakshi Piplani , Puneet Singh , David A. Winkler , Nikolai Petrovsky

The COVID-19 pandemic has severely impacted health systems and economies worldwide. Significant global efforts are therefore ongoing to improve vaccine efficacies, optimize vaccine deployment, and develop new antiviral therapies to combat…

Populations and Evolution · Quantitative Biology 2021-12-21 Rajat Desikan , Pranesh Padmanabhan , Andrzej M. Kierzek , Piet H. van der Graaf

In 2019, the world faced a new challenge: a COVID-19 disease caused by the novel coronavirus, SARS-CoV-2. The virus rapidly spread across the globe, leading to a high rate of mortality, which prompted health organizations to take measures…

Image and Video Processing · Electrical Eng. & Systems 2024-08-08 Kavian Khanjani , Seyed Rasoul Hosseini , Hamid Taheri , Shahrzad Shashaani , Mohammad Teshnehlab

Epidemiological models with constant parameters may not capture satisfactory infection patterns in the presence of pharmaceutical and non-pharmaceutical mitigation measures during a pandemic, since infectiousness is a function of time. In…

Populations and Evolution · Quantitative Biology 2022-05-16 K. D. Olumoyin , A. Q. M. Khaliq , K. M. Furati