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Intraoperative assessment of tissue can be guided through fluorescence imaging which involves systemic dosing with a fluorophore and subsequent examination of the tissue region of interest with a near-infrared camera. This typically…
Tracking and characterizing the blood uptake process within solid pancreatic tumors and the subsequent spatio-temporal distribution of red blood cells are critical to the clinical diagnosis of the cancer. This systematic computational study…
Colorectal endoscopy is important for the early detection and treatment of colorectal cancer and is used worldwide. A computer-aided diagnosis (CAD) system that provides an objective measure to endoscopists during colorectal endoscopic…
We present cytometric classification of live healthy and cancer cells by using the spatial morphological and textural information found in the label-free quantitative phase images of the cells. We compare both healthy cells to primary tumor…
Purpose: The gold standard for colorectal cancer metastases detection in the peritoneum is histological evaluation of a removed tissue sample. For feedback during interventions, real-time in-vivo imaging with confocal laser microscopy has…
Early detection of cancerous tissue is crucial for long-term patient survival. In the head and neck region, a typical diagnostic procedure is an endoscopic intervention where a medical expert manually assesses tissue using RGB camera…
The imaging and subsequent accurate diagnosis of paediatric brain tumours presents a radiological challenge, with magnetic resonance imaging playing a key role in providing tumour specific imaging information. Diffusion weighted and…
This research presents a machine-learning approach for tumor detection in medical images using convolutional neural networks (CNNs). The study focuses on preprocessing techniques to enhance image features relevant to tumor detection,…
Determination of fundamental mechanisms of disease often hinges on histopathology visualization and quantitative image analysis. Currently, the analysis of multi-channel fluorescence tissue images is primarily achieved by manual…
Risk stratification (characterization) of tumors from radiology images can be more accurate and faster with computer-aided diagnosis (CAD) tools. Tumor characterization through such tools can also enable non-invasive cancer staging,…
Digital analysis of mammographic images is a complementary tool to clinical evaluation, commonly used to identify tumors and/or microcalcifications in mammograms. Recent mammographic equipment, can automatically classify them using this…
Dynamic susceptibility-weighted contrast-enhanced (DSC) MRI or perfusion-MRI plays an important role in the non-invasive assessment of tumor vascularity. However, the large number of images provided by the method makes display and…
Laser illumination of tissue results in a characteristic fluorescence emission spectrum whose features depend on the type of tissue, viz., healthy, adenoma or malignant. Hence measurement of the fluorescence is potentially a rapid and…
Wavelet transform of polarized fluorescence spectroscopic data of human breast tissues is found to reliably differentiate normal and malignant tissue types and isolate characteristic biochemical signatures of cancerous tissues, which can…
DSC-MRI perfusion is a medical imaging technique for diagnosing and prognosing brain tumors and strokes. Its analysis relies on mathematical deconvolution, but noise or motion artifacts in a clinical environment can disrupt this process,…
This work explores the use of computer vision for image segmentation and classification of medical fluid samples in transparent containers (for example, tubes, syringes, infusion bags). Handling fluids such as infusion fluids, blood, and…
In this paper, we present a new statistical approach to automatically identify cancer regions in pathological images. The proposed method is built from statistical theory in line with evidence-based medicine. The two core technologies are…
This paper shows results of computer analysis of images in the purpose of finding differences between medical images in order of their classifications in terms of separation malign tissue from a normal and benign tissue. The diagnostics of…
Recent advances in cancer research largely rely on new developments in microscopic or molecular profiling techniques offering high level of detail with respect to either spatial or molecular features, but usually not both. Here, we present…
In this study, a morphological differentiation-based method has been introduced which employs temperature distribution on the tissue surface to detect brain tumor's malignancy. According to the common tumor CT scans, two different scenarios…