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A multilabeled tree (or MUL-tree) is a rooted tree in which every leaf is labelled by an element from some set, but in which more than one leaf may be labelled by the same element of that set. In phylogenetics, such trees are used in…

Populations and Evolution · Quantitative Biology 2018-03-16 Manuel Lafond , Nadia El-Mabrouk , Katharina T. Huber , Vincent Moulton

A phylogenetic birth-and-death model is a probabilistic graphical model for a so-called phylogenetic profile, i.e., the size distribution for a homolog gene family at the terminal nodes of a phylogeny. Profile datasets are used in…

Populations and Evolution · Quantitative Biology 2009-02-06 Miklós Csűrös , István Miklós

Phylogenetic networks are graphs that are used to represent evolutionary relationships between different taxa. They generalize phylogenetic trees since for example, unlike trees, they permit lineages to combine. Recently, there has been…

Populations and Evolution · Quantitative Biology 2025-08-05 Katharina T. Huber , Leo van Iersel , Mark Jones , Vincent Moulton , Leonie Veenema - Nipius

Every weighted tree corresponds naturally to a cooperative game that we call a "tree game"; it assigns to each subset of leaves the sum of the weights of the minimal subtree spanned by those leaves. In the context of phylogenetic trees, the…

Quantitative Methods · Quantitative Biology 2009-09-02 Claus-Jochen Haake , Akemi Kashiwada , Francis Edward Su

Estimating phylogenetic trees is an important problem in evolutionary biology, environmental policy and medicine. Although trees are estimated, their uncertainties are discarded by mathematicians working in tree space. Here we explicitly…

Methodology · Statistics 2017-10-16 Amy D. Willis , Rayna C. Bell

The reliability of a phylogenetic inference method from genomic sequence data is ensured by its statistical consistency. Bayesian inference methods produce a sample of phylogenetic trees from the posterior distribution given sequence data.…

Metric Geometry · Mathematics 2016-06-10 Alex Gavryushkin , Alexei J. Drummond

Phylogenetic mixture models are statistical models of character evolution allowing for heterogeneity. Each of the classes in some unknown partition of the characters may evolve by different processes, or even along different trees. The…

Populations and Evolution · Quantitative Biology 2010-11-19 John A. Rhodes , Seth Sullivant

The evolutionary relationships between species are typically represented in the biological literature by rooted phylogenetic trees. However, a tree fails to capture ancestral reticulate processes, such as the formation of hybrid species or…

Populations and Evolution · Quantitative Biology 2024-12-09 Johanna Heiss , Daniel H. Huson , Mike Steel

Attempting to recognize a tree inside a phylogenetic network is a fundamental undertaking in evolutionary analysis. In the last few years, therefore, tree-based phylogenetic networks, which are defined by a spanning tree called a…

Combinatorics · Mathematics 2020-09-29 Momoko Hayamizu

Decision trees are widely used for interpretable machine learning due to their clearly structured reasoning process. However, this structure belies a challenge we refer to as predictive equivalence: a given tree's decision boundary can be…

Machine Learning · Computer Science 2025-10-15 Hayden McTavish , Zachery Boner , Jon Donnelly , Margo Seltzer , Cynthia Rudin

Computational inference of dated evolutionary histories relies upon various hypotheses about RNA, DNA, and protein sequence mutation rates. Using mutation rates to infer these dated histories is referred to as molecular clock assumption.…

Populations and Evolution · Quantitative Biology 2021-01-11 Lena Collienne , Kieran Elmes , Mareike Fischer , David Bryant , Alex Gavryushkin

Phylogenetic networks provide a more general description of evolutionary relationships than rooted phylogenetic trees. One way to produce a phylogenetic network is to randomly place $k$ arcs between the edges of a rooted binary phylogenetic…

Populations and Evolution · Quantitative Biology 2025-03-19 Michael Fuchs , Mike Steel , Qiang Zhang

A \emph{binary tanglegram} is a drawing of a pair of rooted binary trees whose leaf sets are in one-to-one correspondence; matching leaves are connected by inter-tree edges. For applications, for example, in phylogenetics, it is essential…

Computational Geometry · Computer Science 2010-09-17 Kevin Buchin , Maike Buchin , Jaroslaw Byrka , Martin Nöllenburg , Yoshio Okamoto , Rodrigo I. Silveira , Alexander Wolff

We study varieties that contain unranked tree languages over all alphabets. Trees are labeled with symbols from two alphabets, an unranked operator alphabet and an alphabet used for leaves only. Syntactic algebras of unranked tree languages…

Formal Languages and Automata Theory · Computer Science 2015-10-27 Magnus Steinby , Eija Jurvanen , Antonio Cano

We characterize the compatibility of a collection of unrooted phylogenetic trees as a question of determining whether a graph derived from these trees --- the display graph --- has a specific kind of triangulation, which we call legal. Our…

Discrete Mathematics · Computer Science 2010-04-26 Sudheer Vakati , David Fernández-Baca

Phylogenetic mixture models, in which the sites in sequences undergo different substitution processes along the same or different trees, allow the description of heterogeneous evolutionary processes. As data sets consisting of longer…

Populations and Evolution · Quantitative Biology 2012-07-17 Elizabeth S. Allman , John A. Rhodes , Seth Sullivant

The metric space of phylogenetic trees defined by Billera, Holmes, and Vogtmann, which we refer to as BHV space, provides a natural geometric setting for describing collections of trees on the same set of taxa. However, it is sometimes…

Populations and Evolution · Quantitative Biology 2018-07-12 Gillian Grindstaff , Megan Owen

In order to conduct a statistical analysis on a given set of phylogenetic gene trees, we often use a distance measure between two trees. In a statistical distance-based method to analyze discordance between gene trees, it is a key to decide…

Populations and Evolution · Quantitative Biology 2016-02-05 Jing Xi , Jin Xie , Ruriko Yoshida

In classification and forecasting with tabular data, one often utilizes tree-based models. Those can be competitive with deep neural networks on tabular data and, under some conditions, explainable. The explainability depends on the depth…

Machine Learning · Computer Science 2024-06-05 Jiri Nemecek , Tomas Pevny , Jakub Marecek

In this paper we introduce and study three new measures for efficient discriminative comparison of phylogenetic trees. The NNI navigation dissimilarity $d_{nav}$ counts the steps along a "combing" of the Nearest Neighbor Interchange (NNI)…

Populations and Evolution · Quantitative Biology 2015-10-21 Omur Arslan , Dan P. Guralnik , Daniel E. Koditschek
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