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Solid estimates describing the clinical course of SARS-CoV-2 infections are still lacking due to under-ascertainment of asymptomatic and mild-disease cases. In this work, we quantify age-specific probabilities of transitions between stages…

We analyzed 5,484 close contacts of COVID-19 cases from Italy, all of them tested for SARS-CoV-2 infection. We found an infection fatality ratio of 2.2% (95%CI 1.69-2.81%) and identified male sex, age >70 years, cardiovascular…

Several important aspects related to SARS-CoV-2 transmission are not well known due to a lack of appropriate data. However, mathematical and computational tools can be used to extract part of this information from the available data, like…

Populations and Evolution · Quantitative Biology 2022-04-01 Nicolas Franco , Pietro Coletti , Lander Willem , Leonardo Angeli , Adrien Lajot , Steven Abrams , Philippe Beutels , Christel Faes , Niel Hens

Background School closures and distance learning have been extensively applied to control SARS-CoV-2 transmission. Despite evidence of viral circulation in schools, the contribution of students and of in-person schooling to the transmission…

SARS-CoV-2 has disrupted the life of billions of people around the world since the first outbreak was officially declared in China at the beginning of 2020. Yet, important questions such as how deadly it is or its degree of spread within…

Populations and Evolution · Quantitative Biology 2021-03-01 Beatriz Seoane

Relevance: Laboratory diagnosis of the novel coronavirus (SARS-CoV-2) infection combined with quarantine for contacts of infected individuals affects the spread of SARS-CoV-2 infection and levels of related mortality. Practices for testing…

Populations and Evolution · Quantitative Biology 2020-10-27 Edward Goldstein

An epidemic disease caused by a new coronavirus has spread in Northern Italy with a strong contagion rate. We implement an SEIR model to compute the infected population and number of casualties of this epidemic. The example may ideally…

Populations and Evolution · Quantitative Biology 2020-05-12 Jose' M. Carcione , Juan E. Santos , Claudio Bagaini , Jing Ba

In this letter we study the temporal evolution of the Sars-Cov-2 in Italy. The time window of the real data is between February 24 and March 25. After we upgrade the data until April 1.We perform the analysis with 4 different model and we…

Populations and Evolution · Quantitative Biology 2020-08-26 Gabriele Martelloni , Gianluca Martelloni

In late December 2019, a novel strand of Coronavirus (SARS-CoV-2) causing a severe, potentially fatal respiratory syndrome (COVID-19) was identified in Wuhan, Hubei Province, China and is causing outbreaks in multiple world countries, soon…

Recently, China announced that its "zero-covid" policy would end, which will bring serious challenges to the country's health system. In here we provide simple calculations that allows us to provide an estimate of what is expected as an…

General Economics · Economics 2022-12-29 Carlos Hernandez-Suarez , Efren Murillo-Zamora

In the night of February 20, 2020, the first case of novel coronavirus disease (COVID-19) was confirmed in the Lombardy Region, Italy. In the week that followed, Lombardy experienced a very rapid increase in the number of cases. We analyzed…

Superspreading complicates the study of SARS-CoV-2 transmission. I propose a model for aggregated case data that accounts for superspreading and improves statistical inference. In a Bayesian framework, the model is estimated on German data…

Applications · Statistics 2020-11-10 Patrick W. Schmidt

Measuring the prevalence of active SARS-CoV-2 infections in the general population is difficult because tests are conducted on a small and non-random segment of the population. However, people admitted to the hospital for non-COVID reasons…

Econometrics · Economics 2021-03-23 Daniel W. Sacks , Nir Menachemi , Peter Embi , Coady Wing

Objective: To evaluate the relationship between coronavirus disease 2019 (COVID-19) diagnosis with SARS-CoV-2 variant B.1.1.7 (also known as Variant of Concern 202012/01) and the risk of hospitalisation compared to diagnosis with wildtype…

As a consequence of missing data on tests for infection and imperfect accuracy of tests, reported rates of population infection by the SARS CoV-2 virus are lower than actual rates of infection. Hence, reported rates of severe illness…

Econometrics · Economics 2020-04-27 Charles F. Manski , Francesca Molinari

Moderate to severe post-acute sequelae of SARS-CoV-2 infection (PASC), also called long COVID, is estimated to impact as many as 10% of SARS-CoV-2 infected individuals, representing a chronic condition with a substantial global public…

Methodology · Statistics 2024-10-11 Harrison T. Reeder , Tanayott Thaweethai , Andrea S. Foulkes

We propose a mathematical model with five compartments for the SARS-CoV-2 transmission: susceptible $S$, undetected infected asymptomatic $A$, undetected infected symptomatic $I$, confirmed positive and isolated $L$, and recovered $ R$, for…

Optimization and Control · Mathematics 2020-09-29 Gabriela Marinoschi

Through the use of cutting-edge unsupervised classification techniques from statistics and machine learning, we characterise symptom phenotypes among symptomatic SARS-CoV-2 PCR-positive community cases. We first analyse each dataset in…

Background. During 2021, the COVID-19 pandemic was characterized by the emergence of lineages with increased fitness. For most of these variants, quantitative information is scarce on epidemiological quantities such as the incubation period…

Using recent data from voluntary mass testing, I provide credible bounds on prevalence of SARS-CoV-2 for Austrian counties in early December 2020. When estimating prevalence, a natural missing data problem arises: no test results are…

General Economics · Economics 2020-12-23 Gabriel Ziegler
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