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Insufficiently precise diagnosis of clinical disease is likely responsible for many treatment failures, even for common conditions and treatments. With a large enough dataset, it may be possible to use unsupervised machine learning to…

Current Computer-Aided Diagnosis (CAD) methods mainly depend on medical images. The clinical information, which usually needs to be considered in practical clinical diagnosis, has not been fully employed in CAD. In this paper, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2021-03-11 Songxiao Yang , Xiabi Liu , Zhongshu Zheng , Wei Wang , Xiaohong Ma

Deep learning has shown remarkable results for image analysis and is expected to aid individual treatment decisions in health care. To achieve this, deep learning methods need to be promoted from the level of mere associations to being able…

Machine Learning · Computer Science 2022-05-02 Wouter A. C. van Amsterdam , Marinus J. C. Eijkemans

Machine learning is used in medicine to support physicians in examination, diagnosis, and predicting outcomes. One of the most dynamic area is the usage of patient generated health data from intensive care units. The goal of this paper is…

Diabetes is a worldwide health issue affecting millions of people. Machine learning methods have shown promising results in improving diabetes prediction, particularly through the analysis of diverse data types, namely gene expression data.…

Machine Learning · Computer Science 2024-04-24 Rita T. Sousa , Heiko Paulheim

Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…

Machine Learning · Computer Science 2025-02-26 Sifal Klioui , Sana Sellami , Youssef Trardi

Clinical data from electronic medical records, registries or trials provide a large source of information to apply machine learning methods in order to foster precision medicine, e.g. by finding new disease phenotypes or performing…

Machine Learning · Computer Science 2020-08-17 Maria Hügle , Gabriel Kalweit , Thomas Huegle , Joschka Boedecker

The classification of medical images is a pivotal aspect of disease diagnosis, often enhanced by deep learning techniques. However, traditional approaches typically focus on unimodal medical image data, neglecting the integration of diverse…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Jun-En Ding , Chien-Chin Hsu , Chi-Hsiang Chu , Shuqiang Wang , Feng Liu

Coronary heart disease, which is a form of cardiovascular disease (CVD), is the leading cause of death worldwide. The odds of survival are good if it is found or diagnosed early. The current report discusses a comparative approach to the…

Computer Vision and Pattern Recognition · Computer Science 2021-12-03 Kelvin Kwakye , Emmanuel Dadzie

Algorithmic image-based diagnosis and prognosis of neurodegenerative diseases on longitudinal data has drawn great interest from computer vision researchers. The current state-of-the-art models for many image classification tasks are based…

Computer Vision and Pattern Recognition · Computer Science 2017-09-04 Jie Zhang , Qingyang Li , Richard J. Caselli , Jieping Ye , Yalin Wang

Controlling infectious diseases is a major health priority because they can spread and infect humans, thus evolving into epidemics or pandemics. Therefore, early detection of infectious diseases is a significant need, and many researchers…

Machine Learning · Computer Science 2022-06-16 Eman Yahia Alqaissi , Fahd Saleh Alotaibi , Muhammad Sher Ramzan

Cancer is a leading cause of death in many countries. An early diagnosis of cancer based on biomedical imaging ensures effective treatment and a better prognosis. However, biomedical imaging presents challenges to both clinical institutions…

Computer Vision and Pattern Recognition · Computer Science 2023-01-24 Hosein Barzekar , Yash Patel , Ling Tong , Zeyun Yu

Combined inference for heterogeneous high-dimensional data is critical in modern biology, where clinical and various kinds of molecular data may be available from a single study. Classical genetic association studies regress a single…

Applications · Statistics 2017-03-22 Hélène Ruffieux , Anthony C. Davison , Jörg Hager , Irina Irincheeva

Multiple sclerosis is a disease that affects the brain and spinal cord, it can lead to severe disability and has no known cure. The majority of prior work in machine learning for multiple sclerosis has been centered around using Magnetic…

Machine Learning · Computer Science 2023-09-12 Alexander Norcliffe , Lev Proleev , Diana Mincu , Fletcher Lee Hartsell , Katherine Heller , Subhrajit Roy

Diagnosis of a clinical condition is a challenging task, which often requires significant medical investigation. Previous work related to diagnostic inferencing problems mostly consider multivariate observational data (e.g. physiological…

Computation and Language · Computer Science 2017-01-05 Aaditya Prakash , Siyuan Zhao , Sadid A. Hasan , Vivek Datla , Kathy Lee , Ashequl Qadir , Joey Liu , Oladimeji Farri

Segmentation and classification of cell nuclei in histopathology images using deep neural networks (DNNs) can save pathologists' time for diagnosing various diseases, including cancers, by automating cell counting and morphometric…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Amruta Parulekar , Utkarsh Kanwat , Ravi Kant Gupta , Medha Chippa , Thomas Jacob , Tripti Bameta , Swapnil Rane , Amit Sethi

The ability to predict lung and heart based diseases using deep learning techniques is central to many researchers, particularly in the medical field around the world. In this paper, we present a unique outlook of a very familiar problem of…

Computer Vision and Pattern Recognition · Computer Science 2022-03-30 Sairamvinay Vijayaraghavan , David Haddad , Shikun Huang , Seongwoo Choi

Classical machine learning techniques often struggle with overfitting and unreliable predictions when exposed to novel conditions. Introducing causality into the modelling process offers a promising way to mitigate these challenges by…

Computational Engineering, Finance, and Science · Computer Science 2025-05-28 David Zapata Gonzalez , Marcel Meyer , Oliver Mueller

In clinical trials, identification of prognostic and predictive biomarkers is essential to precision medicine. Prognostic biomarkers can be useful for the prevention of the occurrence of the disease, and predictive biomarkers can be used to…

Methodology · Statistics 2022-06-28 Wencan Zhu , Céline Lévy-Leduc , Nils Ternès

Clinical prediction models (CPMs) are used to predict clinically relevant outcomes or events. Typically, prognostic CPMs are derived to predict the risk of a single future outcome. However, with rising emphasis on the prediction of…

Methodology · Statistics 2020-10-29 Glen P. Martin , Matthew Sperrin , Kym I. E. Snell , Iain Buchan , Richard D. Riley