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Identifying measurable genetic indicators (or biomarkers) of a specific condition of a biological system is a key element of precision medicine. Indeed it allows to tailor diagnostic, prognostic and treatment choice to individual…

Machine Learning · Statistics 2016-12-16 Chloé-Agathe Azencott

Objective: The growing availability of large-scale observational clinical datasets and challenges in conducting randomized controlled trials have spurred enthusiasm in using causal machine learning (ML) for causal inference in observational…

Medical Informatics and the application of modern signal processing in the assistance of the diagnostic process in medical imaging is one of the more recent and active research areas today. This thesis addresses a variety of issues related…

Computer Vision and Pattern Recognition · Computer Science 2009-10-20 Harris Georgiou

An important objective in computational biology is the efficient integration of multi-omics data. The task of integration comes with challenges: multi-omics data are most often unpaired (requiring diagonal integration), partially labeled…

Machine Learning · Computer Science 2025-09-16 Daniel Lepe-Soltero , Thierry Artières , Anaïs Baudot , Paul Villoutreix

The medical imaging community generates a wealth of datasets, many of which are openly accessible and annotated for specific diseases and tasks such as multi-organ or lesion segmentation. Current practices continue to limit model training…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Constantin Ulrich , Fabian Isensee , Tassilo Wald , Maximilian Zenk , Michael Baumgartner , Klaus H. Maier-Hein

Medical automatic diagnosis aims to imitate human doctors in real-world diagnostic processes and to achieve accurate diagnoses by interacting with the patients. The task is formulated as a sequential decision-making problem with a series of…

Machine Learning · Computer Science 2022-06-07 Hongyi Yuan , Sheng Yu

This study presents a machine learning-based framework for heart disease prediction using the heart-disease dataset, comprising 303 samples with 14 features. The methodology involves data preprocessing, model training, and evaluation using…

Machine Learning · Computer Science 2025-05-16 Ali Azimi Lamir , Shiva Razzagzadeh , Zeynab Rezaei

Areas where Artificial Intelligence (AI) & related fields are finding their applications are increasing day by day, moving from core areas of computer science they are finding their applications in various other domains.In recent times…

Machine Learning · Computer Science 2016-07-19 Sahil Sharma , Vinod Sharma , Atul Sharma

Disease forecasting models typically rely on a single data stream, making models brittle when histories are short or noisy. Recent top-performing models have shown that synthesizing multiple reporting systems for the same disease improves…

Machine Learning · Computer Science 2026-05-27 Lauren J Beesley , Alexander C Murph , Dave Osthus , Lauren A Castro

Early detection of patients vulnerable to infections acquired in the hospital environment is a challenge in current health systems given the impact that such infections have on patient mortality and healthcare costs. This work is focused on…

Disorders of consciousness are a heterogeneous mixture of different diseases or injuries. Although some indicators and models have been proposed for prognostication, any single method when used alone carries a high risk of false prediction.…

Neurons and Cognition · Quantitative Biology 2018-09-10 Ming Song , Yi Yang , Jianghong He , Zhengyi Yang , Shan Yu , Qiuyou Xie , Xiaoyu Xia , Yuanyuan Dang , Qiang Zhang , Xinhuai Wu , Yue Cui , Bing Hou , Ronghao Yu , Ruxiang Xu , Tianzi Jiang

Multimodal machine learning integrating histopathology and molecular data shows promise for cancer prognostication. We systematically reviewed studies combining whole slide images (WSIs) and high-throughput omics to predict overall…

Quantitative Methods · Quantitative Biology 2025-07-30 Charlotte Jennings , Andrew Broad , Lucy Godson , Emily Clarke , David Westhead , Darren Treanor

Accurate prediction of cardiovascular diseases remains imperative for early diagnosis and intervention, necessitating robust and precise predictive models. Recently, there has been a growing interest in multi-modal learning for uncovering…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Francesco Girlanda , Olga Demler , Bjoern Menze , Neda Davoudi

The research community continues to seek increasingly more advanced synthetic data generators to reliably evaluate the strengths and limitations of machine learning methods. This work aims to increase the availability of datasets…

Machine Learning · Computer Science 2026-01-30 Joanna Komorniczak

The application of data mining, machine learning and artificial intelligence techniques in the field of diagnostics is not a new concept, and these techniques have been very successfully applied in a variety of applications, especially in…

Machine Learning · Computer Science 2020-08-07 Ayush Khaneja , Siddharth Srivastava , Astha Rai , A S Cheema , P K Srivastava

A common practice in evidence-based decision-making uses estimates of conditional probabilities P(y|x) obtained from research studies to predict outcomes y on the basis of observed covariates x. Given this information, decisions are then…

Econometrics · Economics 2025-12-08 Atheendar S. Venkataramani , Charles F. Manski , John Mullahy

Elucidating the genetic basis of human diseases is a central goal of genetics and molecular biology. While traditional linkage analysis and modern high-throughput techniques often provide long lists of tens or hundreds of disease gene…

Quantitative Methods · Quantitative Biology 2011-06-03 Fantine Mordelet , Jean-Philippe Vert

Clinical diagnosis, which aims to assign diagnosis codes for a patient based on the clinical note, plays an essential role in clinical decision-making. Considering that manual diagnosis could be error-prone and time-consuming, many…

Computation and Language · Computer Science 2021-01-28 Yichao Du , Pengfei Luo , Xudong Hong , Tong Xu , Zhe Zhang , Chao Ren , Yi Zheng , Enhong Chen

Deep learning model trained by imbalanced data may not work satisfactorily since it could be determined by major classes and thus may ignore the classes with small amount of data. In this paper, we apply deep learning based imbalanced data…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Ziqian Luo , Xiangrui Zeng , Zhipeng Bao , Min Xu

Prediction and causal explanation are fundamentally distinct tasks of data analysis. In health applications, this difference can be understood in terms of the difference between prognosis (prediction) and prevention/treatment (causal…

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