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COVID-19 has caused thousands of deaths around the world and also resulted in a large international economic disruption. Identifying the pathways associated with this illness can help medical researchers to better understand the properties…
COVID-19 has challenged health systems to learn how to learn. This paper describes the context, methods and challenges for learning to improve COVID-19 care at one academic health center. Challenges to learning include: (1) choosing a right…
The COVID-19 pandemic represents the most significant public health disaster since the 1918 influenza pandemic. During pandemics such as COVID-19, timely and reliable spatio-temporal forecasting of epidemic dynamics is crucial. Deep…
Because of the rapid spread of COVID-19 to almost every part of the globe, huge volumes of data and case studies have been made available, providing researchers with a unique opportunity to find trends and make discoveries like never…
We analyse prior risk factors for severe, critical or fatal courses of Covid-19 based on a retrospective cohort using claims data of the AOK Bayern. As our main methodological contribution, we avoid prior grouping and pre-selection of…
Classical epidemiological models assume homogeneous populations. There have been important extensions to model heterogeneous populations, when the identity of the sub-populations is known, such as age group or geographical location. Here,…
Coronavirus Disease 2019 (COVID-19) is a rapidly emerging respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Due to the rapid human-to-human transmission of SARS-CoV-2, many healthcare systems…
Health insurance claims data offer a unique opportunity to study disease distribution on a large scale. Challenges arise in the process of accurately analyzing these raw data. One important challenge to overcome is the accurate…
We introduce an extended generalised logistic growth model for discrete outcomes, in which a network structure can be specified to deal with spatial dependence and time dependence is dealt with using an Auto-Regressive approach. A major…
Recent years have seen increasing efforts to forecast infectious disease burdens, with a primary goal being to help public health workers make informed policy decisions. However, there has only been limited discussion of how predominant…
Intermediate Respiratory Care Units (IRCUs) are vital during crises like COVID-19. This study evaluated clinical outcomes and operational dynamics of a new Spanish IRCU with specialized staffing. A prospective cohort study (April-August…
Existing prognostic tools mainly focus on predicting the risk of mortality among patients with coronavirus disease 2019. However, clinical evidence suggests that COVID-19 can result in non-mortal complications that affect patient prognosis.…
In this paper, we apply statistical methods for functional data to explain the heterogeneity in the evolution of number of deaths of Covid-19 over different regions. We treat the cumulative daily number of deaths in a specific region as a…
We investigate patterns of COVID-19 mortality across 20 Italian regions and their association with mobility, positivity, and socio-demographic, infrastructural and environmental covariates. Notwithstanding limitations in accuracy and…
With the emerging COVID-19 crisis, a critical task for public health officials and policy makers is to decide how to prioritize, locate, and allocate scarce resources. To answer these questions, decision makers need to be able to determine…
While COVID-19 is rapidly propagating around the globe, the need for providing real-time forecasts of the epidemics pushes fits of dynamical and statistical models to available data beyond their capabilities. Here we focus on statistical…
This paper introduces new methods to track the offset between two multivariate time series on a continuous basis. We then apply this framework to COVID-19 counts on a state-by-state basis in the United States to determine the progression…
The statistical dynamics of a pathogen within a population depend on a range of factors: population density, the effectiveness and investment into social distancing, public policy measures and non-pharmaceutical interventions (NPIs) are…
Accurately forecasting patient arrivals at Urgent Care Clinics (UCCs) and Emergency Departments (EDs) is important for effective resourcing and patient care. However, correctly estimating patient flows is not straightforward since it…
Intensive Care Units (ICUs) provide critical care and life support for most severely ill and injured patients in the hospital. With the need for ICUs growing rapidly and unprecedentedly, especially during COVID-19, accurately identifying…