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Knowing the infection fatality ratio (IFR) is of crucial importance for evidence-based epidemic management: for immediate planning; for balancing the life years saved against the life years lost due to the consequences of management; and…

Quantitative Methods · Quantitative Biology 2020-08-11 Simon N. Wood , Ernst C. Wit , Matteo Fasiolo , Peter J. Green

Hospitals commonly project demand for their services by combining their historical share of regional demand with forecasts of total regional demand. Hospital-specific forecasts of demand that provide prediction intervals, rather than point…

Applications · Statistics 2020-11-20 Linying Yang , Teng Zhang , Peter Glynn , David Scheinker

Since the COVID-19 pandemic first reached the United States, the case fatality rate has fallen precipitously. Several possible explanations have been floated, including greater detection of mild cases due to expanded testing, shifts in age…

Applications · Statistics 2020-12-14 Cheng Cheng , Helen Zhou , Jeremy C. Weiss , Zachary C. Lipton

We use a simple SIR-like epidemic model which integrates known age-contact patterns for the United States to model the effect of age-targeted mitigation strategies for a COVID-19-like epidemic. We find that, among strategies which end with…

Populations and Evolution · Quantitative Biology 2020-09-09 Maria Chikina , Wesley Pegden

We present a compartmental SEIRD model aimed at forecasting hospital occupancy in metropolitan areas during the current COVID-19 outbreak. The model features asymptomatic and symptomatic infections with detailed hospital dynamics. We model…

Populations and Evolution · Quantitative Biology 2020-06-08 Marcos A. Capistran , Antonio Capella , J. Andres Christen

The generalized logistic equation is used to interpret the COVID-19 epidemic data in several countries: Austria, Switzerland, the Netherlands, Italy, Turkey and South Korea. The model coefficients are calculated: the growth rate and the…

Populations and Evolution · Quantitative Biology 2021-02-03 Efim Pelinovsky , Andrey Kurkin , Oxana Kurkina , Maria Kokoulina , Anastasia Epifanova

The relative case fatality rates (CFRs) between groups and countries are key measures of relative risk that guide policy decisions regarding scarce medical resource allocation during the ongoing COVID-19 pandemic. In the middle of an active…

Quantitative Methods · Quantitative Biology 2022-12-08 Anastasios Nikolas Angelopoulos , Reese Pathak , Rohit Varma , Michael I. Jordan

Amid the ongoing COVID-19 pandemic, whether COVID-19 patients with high risks can be recovered or not depends, to a large extent, on how early they will be treated appropriately before irreversible consequences are caused to the patients by…

Applications · Statistics 2020-07-01 Feng Zhou , Tao Chen , Baiying Lei

While image analysis of chest computed tomography (CT) for COVID-19 diagnosis has been intensively studied, little work has been performed for image-based patient outcome prediction. Management of high-risk patients with early intervention…

Comparing how different populations have suffered under COVID-19 is a core part of ongoing investigations into how public policy and social inequalities influence the number of and severity of COVID-19 cases. But COVID-19 incidence can vary…

Populations and Evolution · Quantitative Biology 2022-11-17 Ryan Wilkinson , Marcus Roper

Over the course of the COVID-19 pandemic, Generalised Additive Models (GAMs) have been successfully employed on numerous occasions to obtain vital data-driven insights. In this paper we further substantiate the success story of GAMs,…

An important parameter for COVID-19 is the case fatality rate (CFR). It has been applied to wide applications, including the measure of the severity of the infection, the estimation of the number of infected cases, risk assessment etc.…

Applications · Statistics 2026-02-10 Donghui Yan , Aiyou Chen , Buqing Yang

We use the logistic function to estimate the number of individuals infected by a virus in a period of time as a function of social isolation level in the previous period of the infection occurrences. Each period is composed by a fixed date…

Physics and Society · Physics 2021-10-28 Adriano J. Holanda

The risk for severe illness and mortality from COVID-19 significantly increases with age. As a result, age-stratified modeling for COVID-19 dynamics is the key to study how to reduce hospitalizations and mortality from COVID-19. By taking…

Populations and Evolution · Quantitative Biology 2021-05-12 Xianhao Chen , Guangyu Zhu , Lan Zhang , Yuguang Fang , Linke Guo , Xinguang Chen

The COVID-19 crisis has shown that we can only prevent the risk of mass contagion through timely, large-scale, coordinated, and decisive actions. However, frequently the models used by experts [from whom decision-makers get their main…

Applications · Statistics 2021-03-08 Mauricio Herrera

The COVID-19 pandemic has created unprecedented challenges worldwide. Strained healthcare providers make difficult decisions on patient triage, treatment and care management on a daily basis. Policy makers have imposed social distancing…

The COVID-19 pandemic has placed immense strain on hospital systems worldwide, leading to critical capacity challenges. This research proposes a two-part framework to optimize hospital capacity through patient relocation strategies. The…

Artificial Intelligence · Computer Science 2026-03-18 Sadaf Tabatabaee , Hicham El Baz , Mohammed Khalil Ghali , Nagendra N. Nagarur

We present modeling of the COVID-19 epidemic in Illinois, USA, capturing the implementation of a Stay-at-Home order and scenarios for its eventual release. We use a non-Markovian age-of-infection model that is capable of handling long and…

Populations and Evolution · Quantitative Biology 2020-11-25 George N. Wong , Zachary J. Weiner , Alexei V. Tkachenko , Ahmed Elbanna , Sergei Maslov , Nigel Goldenfeld

Real-world growth processes, such as epidemic growth, are inherently noisy, uncertain and often involve multiple growth phases. The logistic-sigmoid function has been suggested and applied in the domain of modelling such growth processes.…

Neural and Evolutionary Computing · Computer Science 2020-12-10 Oluwasegun A. Somefun , Kayode Akingbade , Folasade Dahunsi

Using the classical Susceptible-Infected-Recovered epidemiological model, an analytical formula is derived for the number of beds occupied by Covid-19 patients. The analytical curve is fitted to data in Belgium, France, New York City and…

Populations and Evolution · Quantitative Biology 2021-02-22 Gregory Kozyreff