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Recent years have witnessed a growing call for renewed emphasis on neuroscience-inspired approaches in artificial intelligence research, under the banner of NeuroAI. A prime example of this is predictive coding networks (PCNs), based on the…

Machine Learning · Computer Science 2026-03-09 Björn van Zwol , Ro Jefferson , Egon L. van den Broek

Patients with semantic dementia (SD) present with remarkably consistent atrophy of neurons in the anterior temporal lobe and behavioural impairments, such as graded loss of category knowledge. While relearning of lost knowledge has been…

Machine Learning · Computer Science 2025-03-06 Devon Jarvis , Verena Klar , Richard Klein , Benjamin Rosman , Andrew Saxe

Dementia is associated with language disorders which impede communication. Here, we automatically learn linguistic disorder patterns by making use of a moderately-sized pre-trained language model and forcing it to focus on reformulated…

Computation and Language · Computer Science 2023-10-17 Dimitris Gkoumas , Matthew Purver , Maria Liakata

Despite substantial efforts, neural network interpretability remains an elusive goal, with previous research failing to provide succinct explanations of most single neurons' impact on the network output. This limitation is due to the…

Machine Learning · Computer Science 2024-02-01 Simon C. Marshall , Jan H. Kirchner

The backpropagation of error algorithm used to train deep neural networks has been fundamental to the successes of deep learning. However, it requires sequential backward updates and non-local computations, which make it challenging to…

Neural and Evolutionary Computing · Computer Science 2022-02-22 Beren Millidge , Tommaso Salvatori , Yuhang Song , Rafal Bogacz , Thomas Lukasiewicz

Mild cognitive impairment (MCI) leading to dementia results in a constellation of psychiatric disorders including depression, mood disorders, schizophrenia and others. With increasing age, mild cognitive impairment leads to increased…

Neurons and Cognition · Quantitative Biology 2023-08-10 Sheng Mai

A significant number of studies apply acoustic and linguistic characteristics of human speech as prominent markers of dementia and depression. However, studies on discriminating depression from dementia are rare. Co-morbid depression is…

Computation and Language · Computer Science 2022-10-10 Malikeh Ehghaghi , Frank Rudzicz , Jekaterina Novikova

Human language processing relies on the brain's capacity for predictive inference. We present a machine learning framework for decoding neural (EEG) responses to dynamic visual language stimuli in Deaf signers. Using coherence between…

Neurons and Cognition · Quantitative Biology 2025-12-25 Sean C. Borneman , Julia Krebs , Ronnie B. Wilbur , Evie A. Malaia

Dementia, a progressive neurodegenerative disorder, affects memory, reasoning, and daily functioning, creating challenges for individuals and healthcare systems. Early detection is crucial for timely interventions that may slow disease…

Neurons and Cognition · Quantitative Biology 2025-03-04 Sahar Sinene Mehdoui , Abdelhamid Bouzid , Daniel Sierra-Sosa , Adel Elmaghraby

Dementia is under-recognized in the community, under-diagnosed by healthcare professionals, and under-coded in claims data. Information on cognitive dysfunction, however, is often found in unstructured clinician notes within medical records…

This paper reviews predictive coding, from theoretical neuroscience, and variational autoencoders, from machine learning, identifying the common origin and mathematical framework underlying both areas. As each area is prominent within its…

Neural and Evolutionary Computing · Computer Science 2021-10-26 Joseph Marino

Encoding and decoding models are widely used in systems, cognitive, and computational neuroscience to make sense of brain-activity data. However, the interpretation of their results requires care. Decoding models can help reveal whether…

Neurons and Cognition · Quantitative Biology 2019-04-29 Nikolaus Kriegeskorte , Pamela K. Douglas

Predictive coding is an influential theory of cortical function which posits that the principal computation the brain performs, which underlies both perception and learning, is the minimization of prediction errors. While motivated by…

Neurons and Cognition · Quantitative Biology 2020-10-13 Beren Millidge , Alexander Tschantz , Anil Seth , Christopher L Buckley

Predictive coding is a unifying framework for understanding perception, action and neocortical organization. In predictive coding, different areas of the neocortex implement a hierarchical generative model of the world that is learned from…

Neurons and Cognition · Quantitative Biology 2023-05-22 Linxing Preston Jiang , Rajesh P. N. Rao

Automated dementia screening enables early detection and intervention, reducing costs to healthcare systems and increasing quality of life for those affected. Depression has shared symptoms with dementia, adding complexity to diagnoses. The…

One of the most prevalent symptoms among the elderly population, dementia, can be detected by classifiers trained on linguistic features extracted from narrative transcripts. However, these linguistic features are impacted in a similar but…

Machine Learning · Computer Science 2019-09-10 Zining Zhu , Jekaterina Novikova , Frank Rudzicz

Predictive coding has emerged as an influential normative model of neural computation, with numerous extensions and applications. As such, much effort has been put into mapping PC faithfully onto the cortex, but there are issues that remain…

Neurons and Cognition · Quantitative Biology 2023-03-07 Siavash Golkar , Tiberiu Tesileanu , Yanis Bahroun , Anirvan M. Sengupta , Dmitri B. Chklovskii

This paper deals with differentiable dynamical models congruent with neural process theories that cast brain function as the hierarchical refinement of an internal generative model explaining observations. Our work extends existing…

Machine Learning · Computer Science 2021-12-10 André Ofner , Sebastian Stober

Biological neural networks face a formidable task: performing reliable computations in the face of intrinsic stochasticity in individual neurons, imprecisely specified synaptic connectivity, and nonnegligible delays in synaptic…

Neurons and Cognition · Quantitative Biology 2020-06-26 Jonathan Kadmon , Jonathan Timcheck , Surya Ganguli

Aging associated brain decline often result in some kind of dementia. Even when this is a complex brain disorder a physical model can be used in order to describe its general behavior. This model is based in first principles. A…

Neurons and Cognition · Quantitative Biology 2016-07-22 Oscar Sotolongo-Costa , L. M. Gaggero-Sager , J. T. Becker , F. Maestú , O. Sotolongo-Grau