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Recently, how to expand data transmission to reduce cell data and repeated cell transmission has received more and more research attention. In mobile social networks, content popularity prediction has always been an important part of…

Social and Information Networks · Computer Science 2019-10-07 Hao Xu

Stereotactic body radiation therapy (SBRT) for pancreatic cancer requires a skillful approach to deliver ablative doses to the tumor while limiting dose to the highly sensitive duodenum, stomach, and small bowel. Here, we develop…

Modeling the absorbed dose during X-ray imaging is essential for optimizing radiation exposure. Monte Carlo simulations (MCS) are the gold standard for precise 3D dose estimation but require significant computation time. Deep learning…

Medical Physics · Physics 2025-02-14 Maxime Rousselot , Jing Zhang , Didier Benoit , Chi-Hieu Pham , Julien Bert

G-Protein Coupled Receptors (GPCRs) are a big family of eukaryotic cell transmembrane proteins, responsible for numerous biological processes. From a practical viewpoint around 34\% of the drugs approved by the US Food and Drug…

Biomolecules · Quantitative Biology 2022-07-13 Juan Manuel López-Correa , Caroline König , Alfredo Vellido

Purpose: To investigate the validity of two Monte Carlo simulation absolute dosimetry approaches in the case of a small field dedicated `D'-shaped collimator used for the retinoblastoma treatment with external photon beam radiotherapy.…

Medical Physics · Physics 2018-09-25 P. A. Mayorga , L. Brualla , A. Flühs , W. Sauerwein , A. M. Lallena

A novel phase-space source implementation has been designed for GPU-based Monte Carlo dose calculation engines. Due to the parallelized nature of GPU hardware, it is essential to simultaneously transport particles of the same type and…

Medical Physics · Physics 2013-06-21 Reid Townson , Xun Jia , Zhen Tian , Yan Jiang Graves , Sergei Zavgorodni , Steve B Jiang

Radiotherapy treatment planning currently requires many trail-and-error iterations between the planner and treatment planning system, as well as between the planner and physician for discussion/consultation. The physician's preferences for…

Medical Physics · Physics 2019-08-01 Dan Nguyen , Azar Sadeghnejad Barkousaraie , Chenyang Shen , Xun Jia , Steve Jiang

Simulations of optical quantum systems are essential for the development of quantum technologies. However, these simulations are often computationally intensive, especially when repeated evaluations are required for data fitting, parameter…

Purpose: Accurate dose calculation is essential in radiotherapy for precise tumor irradiation while sparing healthy tissue. With the growing adoption of MRI-guided and real-time adaptive radiotherapy, fast and accurate dose calculation on…

In this work, we proposed virtual imaging simulators as an alternative approach to experimental validation of beam range uncertainty in complex patient geometry using a computational model of a human head and a photon-counting CT scanner.…

Medical Physics · Physics 2026-01-05 S. Vrbaški , G. Stanić , S. Molinelli , M. Bhattarai , E. Abadi , M. Ciocca , E. Samei

In radiotherapy, a trade-off exists between computational workload/speed and dose calculation accuracy. Calculation methods like pencil-beam convolution can be much faster than Monte-Carlo methods, but less accurate. The dose difference,…

Medical Physics · Physics 2020-05-18 Yixun Xing , Ph. D. , You Zhang , Ph. D. , Dan Nguyen , Ph. D. , Mu-Han Lin , Ph. D. , Weiguo Lu , Ph. D. , Steve Jiang , Ph. D

Protoacoustic imaging showed great promise in providing real-time 3D dose verification of proton therapy. However, the limited acquisition angle in protoacoustic imaging induces severe artifacts, which significantly impairs its accuracy for…

Medical Physics · Physics 2023-08-14 Yankun Lang , Zhuoran Jiang , Leshan Sun , Liangzhong Xiang , Lei Ren

Time series prediction can be generalized as a process that extracts useful information from historical records and then determines future values. Learning long-range dependencies that are embedded in time series is often an obstacle for…

Neural and Evolutionary Computing · Computer Science 2018-10-25 Yuxiu Hua , Zhifeng Zhao , Rongpeng Li , Xianfu Chen , Zhiming Liu , Honggang Zhang

A probabilistic reconstruction using machine-learning of the decay kinematics of top-quark pairs produced in high-energy proton-proton collisions is presented. A deep neural network whose core consists of a Bidirectional Long Short-Term…

High Energy Physics - Experiment · Physics 2019-09-04 Fardin Syed , Riccardo Di Sipio , Pekka Sinervo

Monte Carlo (MC) is generally considered as the most accurate dose calculation tool for particle therapy. However, a proper description of the beam particles kinematics is a necessary input for a realistic simulation. Such a description can…

Objective. The objective of the presented study was to evaluate the feasibility of a coded-mask (CM) gamma camera for real-time range verification in proton therapy, addressing the need for a precise and efficient method of treatment…

Time-Resolved Spectroscopy (TRS) is a powerful modality for non-invasive characterization of turbid media. However, extracting optical properties, absorption $\mu_a$ and reduced scattering $\mu_s'$, from 3D stochastic measurements remains…

Numerical Analysis · Mathematics 2026-04-14 Joubine Aghili , Rémi Imbach , Anne Pallarès , Philippe Schmitt , Wilfried Uhring

Cancer is a primary cause of morbidity and mortality worldwide. The radiotherapy plays a more and more important role in cancer treatment. In the radiotherapy, the dose distribution maps in patient need to be calculated and evaluated for…

Medical Physics · Physics 2019-10-18 Zhao Peng , Hongming Shan , Tianyu Liu , Xi Pei , Jieping Zhou , Ge Wang , X. George Xu

Machine learning is widely used to analyze biological sequence data. Non-sequential models such as SVMs or feed-forward neural networks are often used although they have no natural way of handling sequences of varying length. Recurrent…

Quantitative Methods · Quantitative Biology 2016-03-14 Søren Kaae Sønderby , Casper Kaae Sønderby , Henrik Nielsen , Ole Winther

To expedite the commissioning process of the proton therapy system at Samsung Medical Center (SMC), we have developed a Monte Carlo simulation model of the proton therapy nozzles using TOPAS. At SMC proton therapy center, we have two gantry…

Medical Physics · Physics 2015-06-01 Kwangzoo Chung , Jinsung Kim , Dae-Hyun Kim , Sunghwan Ahn , Youngyih Han