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We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions,…

Methodology · Statistics 2026-02-11 Zhe Li , Mélanie Prague , Rodolphe Thiébaut , Quentin Clairon

Unsupervised and semi-supervised ML methods such as variational autoencoders (VAE) have become widely adopted across multiple areas of physics, chemistry, and materials sciences due to their capability in disentangling representations and…

Machine Learning · Computer Science 2022-07-04 Arpan Biswas , Rama Vasudevan , Maxim Ziatdinov , Sergei V. Kalinin

Deep energy-based models (EBMs) are very flexible in distribution parametrization but computationally challenging because of the intractable partition function. They are typically trained via maximum likelihood, using contrastive divergence…

Machine Learning · Computer Science 2020-07-22 Lantao Yu , Yang Song , Jiaming Song , Stefano Ermon

Variational autoencoders (VAEs) are one class of generative probabilistic latent-variable models designed for inference based on known data. We develop three variations on VAEs by introducing a second parameterized encoder/decoder pair and,…

Machine Learning · Computer Science 2023-04-06 R. I. Cukier

Deep neural networks with discrete latent variables offer the promise of better symbolic reasoning, and learning abstractions that are more useful to new tasks. There has been a surge in interest in discrete latent variable models, however,…

Machine Learning · Computer Science 2018-07-23 Aurko Roy , Ashish Vaswani , Arvind Neelakantan , Niki Parmar

We introduce Variational Joint Embedding (VJE), a reconstruction-free latent-variable framework for non-contrastive self-supervised learning in representation space. VJE maximizes a symmetric conditional evidence lower bound (ELBO) on…

Machine Learning · Computer Science 2026-04-27 Amin Oji , Paul Fieguth

This work proposes a method for using any generator network as the foundation of an Energy-Based Model (EBM). Our formulation posits that observed images are the sum of unobserved latent variables passed through the generator network and a…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Mitch Hill , Erik Nijkamp , Jonathan Mitchell , Bo Pang , Song-Chun Zhu

Variational Autoencoder is a scalable method for learning latent variable models of complex data. It employs a clear objective that can be easily optimized. However, it does not explicitly measure the quality of learned representations. We…

Machine Learning · Computer Science 2020-05-29 Andriy Serdega , Dae-Shik Kim

The ability to accurately model random fields plays a critical role in science and engineering for problems involving uncertain, spatially-varying quantities such as heterogeneous material properties and turbulent flows. Deep generative…

In this paper, we propose an end-to-end lifelong learning mixture of experts. Each expert is implemented by a Variational Autoencoder (VAE). The experts in the mixture system are jointly trained by maximizing a mixture of individual…

Machine Learning · Computer Science 2021-07-13 Fei Ye , Adrian G. Bors

We motivate Energy-Based Models (EBMs) as a promising model class for continual learning problems. Instead of tackling continual learning via the use of external memory, growing models, or regularization, EBMs change the underlying training…

Machine Learning · Computer Science 2025-03-05 Shuang Li , Yilun Du , Gido M. van de Ven , Igor Mordatch

Variational autoencoders (VAEs) are a standard framework for inducing latent variable models that have been shown effective in learning text representations as well as in text generation. The key challenge with using VAEs is the {\it…

Machine Learning · Computer Science 2020-05-01 Serhii Havrylov , Ivan Titov

Euclidean geometry has historically been the typical "workhorse" for machine learning applications due to its power and simplicity. However, it has recently been shown that geometric spaces with constant non-zero curvature improve…

Machine Learning · Computer Science 2020-02-14 Ondrej Skopek , Octavian-Eugen Ganea , Gary Bécigneul

Recent work in unsupervised learning has focused on efficient inference and learning in latent variables models. Training these models by maximizing the evidence (marginal likelihood) is typically intractable. Thus, a common approximation…

Machine Learning · Computer Science 2021-02-15 Linh Tran , Maja Pantic , Marc Peter Deisenroth

Energy-based models (EBMs) have recently been successful in representing complex distributions of small images. However, sampling from them requires expensive Markov chain Monte Carlo (MCMC) iterations that mix slowly in high dimensional…

Machine Learning · Computer Science 2021-11-08 Zhisheng Xiao , Karsten Kreis , Jan Kautz , Arash Vahdat

The variational autoencoder (VAE) framework remains a popular option for training unsupervised generative models, especially for discrete data where generative adversarial networks (GANs) require workaround to create gradient for the…

Machine Learning · Computer Science 2019-04-24 Jason Chou , Gautam Hathi

Variational Autoencoders (VAEs) have been shown to be remarkably effective in recovering model latent spaces for several computer vision tasks. However, currently trained VAEs, for a number of reasons, seem to fall short in learning…

Machine Learning · Computer Science 2021-07-27 Chandrajit Bajaj , Avik Roy , Haoran Zhang

Multimodal variational autoencoders have demonstrated their ability to learn the relationships between different modalities by mapping them into a latent representation. Their design and capacity to perform any-to-any conditional and…

Machine Learning · Computer Science 2025-02-04 Daniel Wesego , Pedram Rooshenas

Maximum likelihood (ML) learning for energy-based models (EBMs) is challenging, partly due to non-convergence of Markov chain Monte Carlo.Several variations of ML learning have been proposed, but existing methods all fail to achieve both…

Machine Learning · Statistics 2023-04-24 Xinwei Zhang , Zhiqiang Tan , Zhijian Ou

The variational auto-encoder (VAE) is a deep latent variable model that has two neural networks in an autoencoder-like architecture; one of them parameterizes the model's likelihood. Fitting its parameters via maximum likelihood (ML) is…

Machine Learning · Computer Science 2021-06-03 Francisco J. R. Ruiz , Michalis K. Titsias , Taylan Cemgil , Arnaud Doucet