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Automated disease diagnosis using medical image analysis relies on deep learning, often requiring large labeled datasets for supervised model training. Diseases like Acute Myeloid Leukemia (AML) pose challenges due to scarce and costly…
Whole slide image (WSI) refers to a type of high-resolution scanned tissue image, which is extensively employed in computer-assisted diagnosis (CAD). The extremely high resolution and limited availability of region-level annotations make…
Multi-instance learning attempts to learn from a training set consisting of labeled bags each containing many unlabeled instances. Previous studies typically treat the instances in the bags as independently and identically distributed.…
Classification and localization are two pillars of visual object detectors. However, in CNN-based detectors, these two modules are usually optimized under a fixed set of candidate (or anchor) bounding boxes. This configuration significantly…
In statistical learning, many problem formulations have been proposed so far, such as multi-class learning, complementarily labeled learning, multi-label learning, multi-task learning, which provide theoretical models for various real-world…
In this paper, we propose a novel approach to tackle the multiple instance regression (MIR) problem. This problem arises when the data is a collection of bags, where each bag is made of multiple instances corresponding to the same unique…
As a widely used weakly supervised learning scheme, modern multiple instance learning (MIL) models achieve competitive performance at the bag level. However, instance-level prediction, which is essential for many important applications,…
Multiple Instance Learning (MIL) and transformers are increasingly popular in histopathology Whole Slide Image (WSI) classification. However, unlike human pathologists who selectively observe specific regions of histopathology tissues under…
In this paper, we propose the MIML (Multi-Instance Multi-Label learning) framework where an example is described by multiple instances and associated with multiple class labels. Compared to traditional learning frameworks, the MIML…
Multiple Instance Learning (MIL) represents the predominant framework in Whole Slide Image (WSI) classification, covering aspects such as sub-typing, diagnosis, and beyond. Current MIL models predominantly rely on instance-level features…
Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised classification in whole slide image (WSI) based pathology diagnosis. However, the current MIL methods are usually based on independent and identical…
Multiple instance learning (MIL)-based framework has become the mainstream for processing the whole slide image (WSI) with giga-pixel size and hierarchical image context in digital pathology. However, these methods heavily depend on a…
Digital histopathology whole slide images (WSIs) provide gigapixel-scale high-resolution images that are highly useful for disease diagnosis. However, digital histopathology image analysis faces significant challenges due to the limited…
In the realm of digital pathology, multi-magnification Multiple Instance Learning (multi-mag MIL) has proven effective in leveraging the hierarchical structure of Whole Slide Images (WSIs) to reduce information loss and redundant data.…
In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…
In this paper, we propose an extension to an existing algorithm (instance-MIR) which tackles the multiple instance regression (MIR) problem, also known as distribution regression. The MIR setting arises when the data is a collection of…
Multi-instance learning (MIL) is widely used in the computer-aided interpretation of pathological Whole Slide Images (WSIs) to solve the lack of pixel-wise or patch-wise annotations. Often, this approach directly applies "natural image…
In computational pathology, whole-slide image (WSI) classification presents a formidable challenge due to its gigapixel resolution and limited fine-grained annotations. Multiple-instance learning (MIL) offers a weakly supervised solution,…
Many objects in the real world are difficult to describe by a single numerical vector of a fixed length, whereas describing them by a set of vectors is more natural. Therefore, Multiple instance learning (MIL) techniques have been…
Transfer learning from large-scale pre-trained models has become essential for many computer vision tasks. Recent studies have shown that datasets like ImageNet are weakly labeled since images with multiple object classes present are…