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While RNA technologies hold immense therapeutic potential in a range of applications from vaccination to gene editing, the broad implementation of these technologies is hindered by the challenge of delivering these agents effectively. Lipid…

Biomolecules · Quantitative Biology 2023-08-30 Daisy Yi Ding , Yuhui Zhang , Yuan Jia , Jiuzhi Sun

In this work we analyze the evolution of voluntary vaccination in networked populations by entangling the spreading dynamics of an influenza-like disease with an evolutionary framework taking place at the end of each influenza season so…

Physics and Society · Physics 2013-09-11 Alessio Cardillo , Catalina Reyes-Suárez , Fernando Naranjo , Jesús Gómez-Gardeñes

We present an effective immunization strategy for computer networks and populations with broad and, in particular, scale-free degree distributions. The proposed strategy, acquaintance immunization, calls for the immunization of random…

Disordered Systems and Neural Networks · Physics 2007-05-23 Reuven Cohen , Shlomo Havlin , Daniel ben-Avraham

Immunizing a subset of nodes in a network - enabling them to identify and withstand the spread of harmful content - is one of the most effective ways to counter the spread of malicious content. It has applications in network security,…

Social and Information Networks · Computer Science 2019-12-30 Muhammad Ahmad , Sarwan Ali , Juvaria Tariq , Imdadullah Khan , Mudassir Shabbir , Arif Zaman

Quantifying the public/private sector supply of contraceptive methods within countries is vital for effective and sustainable family planning (FP) delivery. In many low and middle-income countries (LMIC), measuring the contraceptive supply…

Methodology · Statistics 2024-09-02 Hannah Comiskey , Leontine Alkema , Niamh Cahill

Motivated by massive outbreaks of COVID-19 that occurred even in populations with high vaccine uptake, we propose a novel multi-population temporal network model for the spread of recurrent epidemic diseases. We study the effect of human…

Dynamical Systems · Mathematics 2022-09-19 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

Tanker-based distribution systems have been prevalent in developing countries to supply clean and pure water in different regions. To efficiently operate such tanker service systems, a large fleet of tanker trucks are required to transport…

Optimization and Control · Mathematics 2024-08-05 Abhilasha Maheshwari , Shamik Misra , Ravindra Gudi , Senthilmurugan Subbiah

Recently in Online Social Networks (OSNs), the Least Cost Influence (LCI) problem has become one of the central research topics. It aims at identifying a minimum number of seed users who can trigger a wide cascade of information…

Social and Information Networks · Computer Science 2016-06-30 Huiyuan Zhang , Dung T. Nguyen , Soham Das , Huiling Zhang , My T. Thai

The possibility of flexibly assigning spectrum resources with channels of different sizes greatly improves the spectral efficiency of optical networks, but can also lead to unwanted spectrum fragmentation.We study this problem in a scenario…

Networking and Internet Architecture · Computer Science 2018-04-30 Alexander Erreygers , Cristina Rottondi , Giacomo Verticale , Jasper De Bock

With the present highly infectious dominant SARS-CoV-2 strain of B1.1.529 or Omicron spreading around the globe, there is concern that the COVID-19 pandemic will not end soon and that it will be a race against time until a more contagious…

Populations and Evolution · Quantitative Biology 2022-04-26 Chottiwatt Jittprasong

Voluntary vaccination is essential to protect oneself from infection and suppress the spread of infectious diseases. Voluntary vaccination behavior is influenced by factors such as age and interaction patterns. Differences in health…

Physics and Society · Physics 2024-12-11 Yanyi Nie , Tao Lin , Yanbing Liu , Wei Wang

Inspired by Minority Games, we constructed a novel individual-level game of adaptive decision-making based on the dilemma of deciding whether to participate in voluntary influenza vaccination programs. The proportion of the population…

Populations and Evolution · Quantitative Biology 2007-05-23 Raffaele Vardavas , Romulus Breban , Sally Blower

The vaccination game is a social dilemma that refers to the conundrum individuals face (to get immunized or not) when the population is exposed to an infectious disease. The model has recently gained much traction due to the COVID-19…

Physics and Society · Physics 2023-02-24 Colin Benjamin , Arjun Krishnan U M

Childhood vaccination is a cornerstone of public health, yet disparities in vaccination coverage persist across England. These disparities are shaped by complex interactions among various factors, including geographic, demographic,…

Machine Learning · Computer Science 2025-04-21 Amin Noroozi , Sidratul Muntaha Esha , Mansoureh Ghari

The paper uses machine learning and mathematical modeling to predict future vaccine distribution and solve the problem of allocating vaccines to different types of hospitals. They collected data and analyzed it, finding factors such as…

Computers and Society · Computer Science 2023-06-13 Baiqiao Yin , Jiaqing Yuan , Weichen Lv , Jiehui Huang , Guian Fang

This work presents a novel Model Predictive Control (MPC) approach to develop an optimal age-structured vaccination strategy for the containment of COVID-19 in Wallonia, Belgium. The proposed MPC framework is designed to minimize deaths,…

Optimization and Control · Mathematics 2026-02-17 Candy Sonveaux , Morgane Dumont , Mirko Fiacchini , Mohamad Ajami

This research is about COVID-19, which is a contagious virus that reached many countries, including Lebanon. Monitoring the outbreak, researchers have been involved in introducing COVID-19 targeting vaccines. Already facing financial and…

Applications · Statistics 2023-12-22 Sarkis Der Wartanian , Baydaa Al Ayoubi

We consider optimization problems with uncertain constraints that need to be satisfied probabilistically. When data are available, a common method to obtain feasible solutions for such problems is to impose sampled constraints, following…

Optimization and Control · Mathematics 2020-07-09 Henry Lam , Fengpei Li

During the COVID-19 pandemic, there were over three million infections in Los Angeles County (LAC). To facilitate distribution when vaccines first became available, LAC set up six mega-sites for dispensing a large number of vaccines to the…

Optimization and Control · Mathematics 2025-02-27 Suyanpeng Zhang , Sze-chuan Suen , Han Yu , Maged Dessouky , Fernando Ordonez

Predictive contagion models are ubiquitous in epidemiology, social sciences, engineering, and management. This paper formulates a prescriptive contagion analytics model where a decision-maker allocates shared resources across multiple…

Optimization and Control · Mathematics 2023-10-24 Alexandre Jacquillat , Michael Lingzhi Li , Martin Ramé , Kai Wang