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The effect of membrane viscosity on the dynamics of vesicles in shear flow is studied. We present a new simulation technique, which combines three-dimensional multi-particle collision dynamics for the solvent with a dynamically-triangulated…

Soft Condensed Matter · Physics 2009-11-10 Hiroshi Noguchi , Gerhard Gompper

Numerical simulations of vesicle suspensions are performed in two dimensions to study their dynamical and rheological properties. An hybrid method is adopted, which combines a mesoscopic approach for the solvent with a curvature-elasticity…

Soft Condensed Matter · Physics 2015-06-18 A. Lamura , G. Gompper

We present rheology experiments on dilute solutions of vesicles and red blood cells (RBC). Varying the viscosity ratio $\lambda$ between internal and external fluids, the microscopic dynamics of suspended objects can be qualitatively…

Soft Condensed Matter · Physics 2007-07-31 Victoria Vitkova , Maud-Alix Mader , Chaouqi Misbah , Thomas Podgorski

We study a simple model of shear banding in which the flow-induced phase is destabilised by coupling between flow and microstructure (wormlike micellar length). By varying the strength of the instability and the applied shear rate, we find…

Soft Condensed Matter · Physics 2007-05-23 Suzanne Fielding , Peter Olmsted

Background and Objective: The role of red blood cell dynamics is emphasised in certain cardiovascular diseases, and thus needs to be closely studied. A multiphase model of blood flow allows the resolution of locally varying density of red…

Fluid Dynamics · Physics 2021-10-07 Konstantinos G. Lyras , Jack Lee

Thrombosis is a common complication following the surgical implantation of blood contacting devices, and is strongly influenced by the phenomenon of near-wall enrichment of platelets. This paper describes a multi-constituent continuum…

Fluid Dynamics · Physics 2017-05-09 Wei-Tao Wu , Nadine Aubry , James F. Antaki , Mehrdad Massoudi

Growing living cultures of Escherichia coli bacteria were investigated using real-time in situ rheology and rheo-imaging measurements. In the early stages of growth (lag phase), and when subjected to a constant stationary shear, the…

Biological Physics · Physics 2016-12-21 R. Portela , P. Patrício , P. L. Almeida , R. G. Sobral , J. M. Franco , C. R. Leal

Computational Fluid Dynamics (CFD) is currently used to design and improve the hydraulic properties of biomedical devices, wherein the large scale blood circulation needs to be simulated by accounting for the mechanical response of red…

Fluid Dynamics · Physics 2024-12-24 F. Guglietta , M. Behr , L. Biferale , G. Falcucci , M. Sbragaglia

The dynamics of a nucleate cell in shear flow is of great relevance in cancer cells and circulatory tumor cells where they dominate the dynamics of blood. Buoyed by the success of Giant Unilamellar vesicles in explaining the dynamics of…

Soft Condensed Matter · Physics 2018-12-04 Kumari Priti Sinha , Rochish M Thaokar

The multi-cellular hydrodynamic interactions play a critical role in the phenomenology of blood flow in the microcirculation. A fast algorithm has been developed to simulate large numbers of cells modeled as elastic thin membranes. For red…

Fluid Dynamics · Physics 2008-10-14 Amir H. G. Isfahani , Hong Zhao , Jonathan B. Freund

The dynamics of single red blood cells (RBCs) determine microvascular blood flow by adapting their shape to the flow conditions in the narrow vessels. In this study, we explore the dynamics and shape transitions of RBCs on the cellular…

The reversible aggregation of red blood cells (RBCs) is a process of erythrocytes clumping that strongly influences the rheological properties of blood. The adhesion of RBCs has been studied extensively in the frame of cell-to-cell…

Biological Physics · Physics 2017-10-09 Alexey Popov , Tatiana Avsievich , Alexander Bykov , Igor Meglinski

Deterministic lateral displacement (DLD) microfluidic devices promise versatile and precise processing of biological samples. However, this prospect has been realized so far only for rigid spherical particles and remains limited for…

Soft Condensed Matter · Physics 2024-06-03 Wei Chien , Zunmin Zhang , Gerhard Gompper , Dmitry A. Fedosov

Multiphase shear flows often show banded structures that affect the global behavior of complex fluids e.g. in microdevices. Here we investigate numerically the banding of emulsions, i.e. the formation of regions of high and low volume…

Fluid Dynamics · Physics 2020-04-30 Francesco De Vita , Marco Edoardo Rosti , Sergio Caserta , Luca Brandt

Centrifugation of biological matter in density gradient solutions is a standard method for separating cell types or components. It is also used to separate red blood cells (RBCs) by age, as they lose water and become denser over their…

Soft Condensed Matter · Physics 2026-02-09 Felix Maurer , Camila Romero , Nikolas Lerch , Thomas John , Lars Kaestner , Christian Wagner , Alexis Darras

Bacteria suspension exhibits a wide range of collective phenomena arising from interactions between individual cells. Here we show Serratia marcescens cells near an air-liquid interface spontaneously aggregate into dynamic clusters through…

Soft Condensed Matter · Physics 2015-09-30 Xiao Chen , Xiang Yang , Mingcheng Yang , Hepeng Zhang

Dry granular material flowing on rough inclines can experience a self-induced Rayleigh-Taylor (RT) instability followed by the spontaneous emergence of convection cells. For this to happen, particles are different in size and density, the…

Soft Condensed Matter · Physics 2020-05-06 Umberto d'Ortona , Nathalie Thomas

We report a numerical study addressing the dynamics of compound vesicles confined in a channel under shear flow. The system comprises a smaller vesicle embedded within a larger one and can be used to mimic, for example, leukocytes or…

Soft Condensed Matter · Physics 2025-12-11 A. Lamura

Via computer simulations, we provide evidence that the shear rate induced red blood cell tumbling-to-tank-treading transition also occurs at quite high volume fractions, where collective effects are important. The transition takes place as…

Soft Condensed Matter · Physics 2013-12-13 Timm Krüger , Markus Gross , Dierk Raabe , Fathollah Varnik

A sequence of two and three-dimensional simulations is conducted for the double diffusive convection (DDC) flows in the diffusive regime subjected to an imposed shear. The flow is confined between two horizontal plates which are maintained…

Fluid Dynamics · Physics 2022-01-12 Yantao Yang , Roberto Verzicco , Detlef Lohse , C. P. Caulfield