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We investigate the shear thinning of red blood cell - dextran suspensions. Microscopic images show that at low polymer concentration, aggregation increases with increasing concentration until it reaches a maximum and then decreases again to…

Soft Condensed Matter · Physics 2015-10-13 Daniel Flormann , Katharina Schirra , Thomas Podgorski , Christian Wagner

Red blood cells (RBCs) are the major component of blood and the flow of blood is dictated by that of RBCs. We employ vesicles, which consist of closed bilayer membranes enclosing a fluid, as a model system to study the behavior of RBCs…

Chaotic Dynamics · Physics 2015-06-22 Othmane Aouane , Marine Thiebaud , Abdelilah Benyoussef , Christian Wagner , Chaouqi Misbah

We present experiments on RBCs that flow through microcapillaries under physiological conditions. We show that the RBC clusters form as a subtle imbrication between hydrodynamics interaction and adhesion forces because of plasma proteins.…

The red blood cell (RBC) membrane is composed of a lipid bilayer and a cytoskeleton interconnected by protein junction complexes, allowing for potential sliding between the lipid bilayer and the cytoskeleton. Despite this biological…

Fluid Dynamics · Physics 2024-01-23 V. Puthumana , P. G. Chen , M. Leonetti , R. Lasserre , M. Jaeger

We reveal that under moderate shear stress (of the order of 0.1 Pa) red blood cells present an oscillation of their inclination (swinging) superimposed to the long-observed steady tanktreading (TT) motion. A model based on a fluid ellipsoid…

Biological Physics · Physics 2009-11-13 Manouk Abkarian , Magalie Faivre , Annie Viallat

Red blood cells (RBCs) are responsible for transporting oxygen and various metabolites to tissues and organs, as well as removing waste. Several cardiovascular diseases can impair these functions. For instance, in diabetes, increased RBC…

Biological Physics · Physics 2025-01-08 Mehdi Abbasi , Chaouqi Misbah

The study of vesicles under flow, a model system for red blood cells (RBCs), is an essential step in understanding various intricate dynamics exhibited by RBCs in vivo and in vitro. Quantitative 3D analyses of vesicles under flow are…

Soft Condensed Matter · Physics 2009-12-24 Thierry Biben , Alexander Farutin , Chaouqi Misbah

The impact of cell segregation and margination in blood disorders on microcirculatory hemodynamics within bifurcated vessels are physiologically significant, yet poorly understood. This study presents a comprehensive computational…

Biological Physics · Physics 2025-01-09 Xiaopo Cheng , Christina Caruso , Wilbur A. Lam , Michael D. Graham

Erythrocyte Sedimentation Rate (ESR) is a clinical parameter used as a non-specific marker for inflammation, and recent studies have shown that it is linked to the collapse of the gel formed by red blood cells (RBCs) at physiological…

Soft Condensed Matter · Physics 2023-07-07 Thomas John , Lars Kaestner , Christian Wagner , Alexis Darras

Red blood cells are known to form aggregates in the form of rouleaux. This aggregation process is believed to be reversible, but there is still no full understanding on the binding mechanism. There are at least two competing models, based…

Biological Physics · Physics 2015-06-17 C. Wagner , P. Steffen , S. Svetina

A mixed suspension of red blood cells (RBCs) and microparticles flows through a cylindrical channel with a constriction mimicking a stenosed blood vessel. Our three-dimensional Lattice-Boltzmann simulations show that the RBCs are depleted…

Fluid Dynamics · Physics 2017-02-01 Christian Bächer , Lukas Schrack , Stephan Gekle

The fluid dynamics video that is presented here outlines recent advances in the simulation of multiphase cellular blood flow through the direct numerical simulations of deformable red blood cells (RBCs) demonstrated through several…

Fluid Dynamics · Physics 2009-10-20 Jonathan R. Clausen , Daniel A. Reasor , Cyrus K. Aidun

The flow behavior of blood in microvessels is directly associated with tissue perfusion and oxygen delivery. Current efforts on modeling blood flow have primarily focused on the flow properties of blood with red blood cells (RBCs) having a…

Soft Condensed Matter · Physics 2024-06-03 Wei Chien , Gerhard Gompper , Dmitry A. Fedosov

We present a numerical analysis of the rheology of a suspension of red blood cells (RBCs) for different volume fractions in a wall-bounded, effectively inertialess, small amplitude oscillatory shear (SAOS) flow for a wide range of applied…

Fluid Dynamics · Physics 2024-04-08 Naoki Takeishi , Marco Edoardo Rosti , Naoto Yokoyama , Luca Brandt

Vesicles under a shear flow exhibit a tank-treading motion of their membrane, while their long axis points with an angle < 45 degrees with respect to the shear stress if the viscosity contrast between the interior and the exterior is not…

Biological Physics · Physics 2009-11-10 F. Rioual , T. Biben , C. Misbah

Understanding how red blood cell (RBC) suspensions navigate porous materials is critical for for both fundamental physiology, such as maternal-fetal exchange in the placenta, and transformative biomedical applications, including rapid,…

Soft Condensed Matter · Physics 2025-09-03 Sampad Laha , Ananta Kumar Nayak , Alexander Farutin , Suman Chakraborty , Chaouqi Misbah

Motivated by the reported peculiar dynamics of a red blood cell in shear flow, we develop an analytical theory for the motion of a nearly--spherical fluid particle enclosed by a visco--elastic incompressible interface in linear flows. The…

Fluid Dynamics · Physics 2010-07-06 Petia M. Vlahovska , Yuan-nan Young , Gerrit Danker , Chaouqi Misbah

We study the deformation and motion of an erythrocyte in fluid flows via a lattice Boltzmann method. To this purpose, the bending rigidity and the elastic modulus of isotropic dilation are introduced and incorporated with the lattice…

Fluid Dynamics · Physics 2007-05-23 Huabing Li , Houhui Yi , Xiaowen Shan , Haiping Fang

We investigate the dynamics of the Red Blood Cell (RBC) in microfluidic channels under oscillatory flows. The simulations employ a hybrid continuum-particle approach, in which the cell membrane and cytosol fluid are modeled using…

Fluid Dynamics · Physics 2023-07-18 Lahcen Akerkouch , Trung Bao Le

Vesicles under shear flow exhibit various dynamics: tank-treading ($tt$), tumbling ($tb$) and vacillating-breathing ($vb$). A consistent higher order theory reveals a direct bifurcation from $tt$ to $tb$ if $C_a\equiv \tau \dot\gamma $ is…

Soft Condensed Matter · Physics 2009-11-13 Gerrit Danker , Thierry Biben , Thomas Podgorski , Claude Verdier , Chaouqi Misbah