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In this work, the SIR epidemiological model is reformulated so to highlight the important {\em effective reproduction number}, as well as to account for the {\em generation time}, inverse of the {\em incidence rate}, and the {\em infectious…

Populations and Evolution · Quantitative Biology 2021-07-27 Ignazio Lazzizzera

Coronavirus COVID-19 spreads through the population mostly based on social contact. To gauge the potential for widespread contagion, to cope with associated uncertainty and to inform its mitigation, more accurate and robust modelling is…

The mathematical modeling of infectious diseases is a fundamental research field for the planning of strategies to contain outbreaks. The models associated with this field of study usually have exponential prior assumptions in the number of…

Signal Processing · Electrical Eng. & Systems 2020-07-02 Jhony H. Giraldo , Thierry Bouwmans

We propose a mathematical model based on probability theory to optimize COVID-19 testing by a multi-step batch testing approach with variable batch sizes. This model and simulation tool dramatically increase the efficiency and efficacy of…

Methodology · Statistics 2021-01-11 Hongshik Ahn , Haoran Jiang , Xiaolin Li

We consider the SIR epidemiological model applied to the evolution of COVID-19 with two approaches. In the first place we fit a global SIR model, with time delay, and constant parameters throughout the outbreak, including the contagion…

Populations and Evolution · Quantitative Biology 2020-06-23 Nana Geraldine Cabo Bizet , Damián Kaloni Mayorga Peña

Since the inception of the SARS - CoV - 2 (COVID - 19) novel coronavirus, a lot of time and effort is being allocated to estimate the trajectory and possibly, forecast with a reasonable degree of accuracy, the number of cases, recoveries,…

Applications · Statistics 2024-05-21 Agniva Das , Kunnummal Muralidharan

In this paper, we estimate the time-varying COVID-19 contact rate of a Susceptible-Infected-Recovered (SIR) model. Our measurement of the contact rate is constructed using data on actively infected, recovered and deceased cases. We propose…

Econometrics · Economics 2022-08-11 Sokbae Lee , Yuan Liao , Myung Hwan Seo , Youngki Shin

The effective reproduction number is an important descriptor of an infectious disease epidemic. In small populations, ideally we would estimate the effective reproduction number using a Markov Jump Process (MJP) model of the spread of…

The estimation of unknown parameters in simulations, also known as calibration, is crucial for practical management of epidemics and prediction of pandemic risk. A simple yet widely used approach is to estimate the parameters by minimizing…

Methodology · Statistics 2023-06-26 Chih-Li Sung , Ying Hung

In epidemiology, the effective reproduction number $R_e$ is used to characterize the growth rate of an epidemic outbreak. In this paper, we investigate properties of $R_e$ for a modified SEIR model of COVID-19 in the city of Houston, TX…

Populations and Evolution · Quantitative Biology 2021-04-22 Christopher Thron , Vianney Mbazumutima , Luis Vargas Tamayo , Leonard Todjihounde

The novel coronavirus disease (COVID-19) is a public health problem once according to the World Health Organization up to June 10th, 2020, more than 7.1 million people were infected, and more than 400 thousand have died worldwide. In the…

Populations and Evolution · Quantitative Biology 2020-07-22 Ramon Gomes da Silva , Matheus Henrique Dal Molin Ribeiro , Viviana Cocco Mariani , Leandro dos Santos Coelho

In this paper we introduce an agent-based model together with a particle filter approach for studying the spread of COVID-19. Investigations are performed on the metropolis of Tokyo, but other cities, regions or countries could have been…

Numerical Analysis · Mathematics 2021-09-02 C. Sun , S. Richard , T. Miyoshi

Several key metrics in public health convey the probability that a primary event will lead to a more serious secondary event in the future. These "severity rates" can change over the course of an epidemic in response to shifting conditions…

In this paper, we propose a new real-time differential virus transmission model, which can give more accurate and robust short-term predictions of COVID-19 transmitted infectious disease with benefits of near-term trend projection.…

Populations and Evolution · Quantitative Biology 2020-05-05 Sheldon X. D. Tan , Liang Chen

Understanding the spread of infectious diseases such as COVID-19 is crucial for informed decision-making and resource allocation. A critical component of disease behavior is the velocity with which disease spreads, defined as the rate of…

Applications · Statistics 2025-12-23 Fernando Rodriguez Avellaneda , Jorge Mateu , Paula Moraga

We propose a deterministic SAIVRD model and a stochastic SARV model of the epidemic COVID-19 involving asymptomatic infections and vaccinations to conduct data forecasts using time-dependent parameters. The forecast by our deterministic…

Populations and Evolution · Quantitative Biology 2022-09-28 Bo-Sheng Chen , Zong-Ying Wu , Yen-Jia Chen , Jann-Long Chern

Count-valued autoregressions are widely used to analyse time-series of reported infectious-disease cases because of their close connection with discrete-time transmission models. However, when such models are applied directly to…

Applications · Statistics 2025-09-16 Justin J. Slater , Sindi Bebeziqi

In this paper, we develop a method to estimate the infection-rate of a disease, over a region, as a field that varies in space and time. To do so, we use time-series of case-counts of symptomatic patients as observed in the areal units that…

Applications · Statistics 2024-06-19 Cosmin Safta , Wyatt Bridgman , Jaideep Ray

Since the beginning of the epidemic, daily reports of CoViD-19 cases, hospitalizations, and deaths from around the world have been publicly available. This paper describes methods to characterize broad features of the spread of the disease,…

Physics and Society · Physics 2020-07-15 Dean Karlen

In this research, we provide a mathematical analysis for the novel coronavirus responsible for COVID-19, which continues to be a big source of threat for humanity. Our fractional-order analysis is carried out using a non-singular kernel…

Dynamical Systems · Mathematics 2021-11-02 Anwarud Din , Amir Khan , Anwar Zeb , Moulay Rchid Sidi Ammi , Mouhcine Tilioua , Delfim F. M. Torres