Related papers: SAveRUNNER: a network-based algorithm for drug rep…

The Coronavirus disease 2019 (COVID-19) has affected several million people. With the outbreak of the epidemic, many researchers are devoting themselves to the COVID-19 screening system. The standard practices for rapid risk screening of…

This technical report proposes the use of a deep convolutional neural network as a preliminary diagnostic method in the analysis of chest computed tomography images from patients with symptoms of Severe Acute Respiratory Syndrome (SARS) and…

Polypharmacy, the concurrent use of multiple drugs to treat a single condition, is common in patients managing multiple or complex conditions. However, as more drugs are added to the treatment plan, the risk of adverse drug events (ADEs)…

The worldwide spread of pneumonia caused by a novel coronavirus poses an unprecedented challenge to the world's medical resources and prevention and control measures. Covid-19 attacks not only the lungs, making it difficult to breathe and…

The novel Wuhan coronavirus known as SARS-CoV-2 has brought almost unprecedented effects for a non-wartime setting, hitting social, economic and health systems hard.~ Being able to bring to bear pharmaceutical interventions to counteract…

Target selection is crucial in pharmaceutical drug discovery, directly influencing clinical trial success. Despite its importance, drug development remains resource-intensive, often taking over a decade with significant financial costs.…

One of the critical tools for early detection and subsequent evaluation of the incidence of lung diseases is chest radiography. This study presents a real-world implementation of a convolutional neural network (CNN) based Carebot Covid app…

The coronavirus disease 2019 (COVID-19) pandemic has exerted a profound impact on patients with end-stage renal disease relying on kidney dialysis to sustain their lives. Motivated by a request by the U.S. Centers for Medicare & Medicaid…

Novel Coronavirus disease (COVID-19) is an extremely contagious and quickly spreading Coronavirus infestation. Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS), which outbreak in 2002 and 2011, and the…

To shorten the time required to find effective new drugs, like antivirals, a key parameter to consider is membrane permeability, as a compound intended for an intracellular target with poor permeability will have low efficacy. Here, we…

The novel coronavirus (SARS-CoV-2) has led to a pandemic. The current testing regime based on Reverse Transcription-Polymerase Chain Reaction for SARS-CoV-2 has been unable to keep up with testing demands, and also suffers from a relatively…

Coronavirus is a large virus family consisting of diverse viruses, some of which disseminate among mammals and others cause sickness among humans. COVID-19 is highly contagious and is rapidly spreading, rendering its early diagnosis of…

The ongoing global pandemic of Coronavirus Disease 2019 (COVID-19) poses a serious threat to public health and the economy. Rapid and accurate diagnosis of COVID-19 is crucial to prevent the further spread of the disease and reduce its…

Since the classification of COVID-19 as a global pandemic, there have been many attempts to treat and contain the virus. Although there is no specific antiviral treatment recommended for COVID-19, there are several drugs that can…

Corona virus or COVID-19 is a pandemic illness, which has influenced more than million of causalities worldwide and infected a few large number of individuals .Innovative instrument empowering quick screening of the COVID-19 contamination…

The outbreak of COVID-19 disease caused more than 100,000 deaths so far in the USA alone. It is necessary to conduct an initial screening of patients with the symptoms of COVID-19 disease to control the spread of the disease. However, it is…

The recent outbreak of SARS COV-2 gave us a unique opportunity to study for a non interventional and sustainable AI solution. Lung disease remains a major healthcare challenge with high morbidity and mortality worldwide. The predominant…

COVID-19 is a virus with high transmission rate that demands rapid identification of the infected patients to reduce the spread of the disease. The current gold-standard test, Reverse-Transcription Polymerase Chain Reaction (RT-PCR), has a…

Drug combination therapy has become a increasingly promising method in the treatment of cancer. However, the number of possible drug combinations is so huge that it is hard to screen synergistic drug combinations through wet-lab…

The race to meet the challenges of the global pandemic has served as a reminder that the existing drug discovery process is expensive, inefficient and slow. There is a major bottleneck screening the vast number of potential small molecules…