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The accurate prediction of B-cell epitopes is critical for guiding vaccine development against infectious diseases, including SARS and COVID-19. This study explores the use of a deep neural network (DNN) model to predict B-cell epitopes for…

Machine Learning · Computer Science 2024-12-03 Xinyu Shi , Yixin Tao , Shih-Chi Lin

With the periodic rise and fall of COVID-19 and numerous countries being affected by its ramifications, there has been a tremendous amount of work that has been done by scientists, researchers, and doctors all over the world. Prompt…

Machine Learning · Computer Science 2021-12-17 Ismail Shahin , Ali Bou Nassif , Mohamed Bader Alsabek

Background: Network propagation has been widely used for nearly 20 years to predict gene functions and phenotypes. Despite the popularity of this approach, little attention has been paid to the question of provenance tracing in this…

Coronavirus Disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 virus (SARS-CoV-2). The virus transmits rapidly; it has a basic reproductive number R of 2.2-2.7. In March 2020, the World Health Organization…

Image and Video Processing · Electrical Eng. & Systems 2021-07-02 Vishal Sharma , Curtis Dyreson

COVID-19 spread across the globe at an immense rate has left healthcare systems incapacitated to diagnose and test patients at the needed rate. Studies have shown promising results for detection of COVID-19 from viral bacterial pneumonia in…

Image and Video Processing · Electrical Eng. & Systems 2020-10-14 Saman Motamed , Patrik Rogalla , Farzad Khalvati

Coronavirus disease 2019 (COVID-19) has emerged the need for computer-aided diagnosis with automatic, accurate, and fast algorithms. Recent studies have applied Machine Learning algorithms for COVID-19 diagnosis over chest X-ray (CXR)…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Aysen Degerli , Mete Ahishali , Serkan Kiranyaz , Muhammad E. H. Chowdhury , Moncef Gabbouj

The COVID-19 global pandemic has resulted in international efforts to understand, track, and mitigate the disease, yielding a significant corpus of COVID-19 and SARS-CoV-2-related publications across scientific disciplines. As of May 2020,…

Information Retrieval · Computer Science 2020-06-18 Andre Esteva , Anuprit Kale , Romain Paulus , Kazuma Hashimoto , Wenpeng Yin , Dragomir Radev , Richard Socher

Mathematical models of SARS-CoV-2 spread are used for guiding the design of mitigation steps aimed at containing and decelerating the contagion, and at identifying impending breaches of health care system surge capacity. The challenges of…

Populations and Evolution · Quantitative Biology 2020-06-17 Daniela Calvetti , Alexander Hoover , Johnie Rose , Erkki Somersalo

Background: The COVID-19 pandemic clock is ticking and the survival of many of mankind's modern institutions and or survival of many individuals is at stake. There is a need for treatments to significantly reduce the morbidity and mortality…

Genomics · Quantitative Biology 2020-12-08 Ali Ebrahimpour Boroojeny , Hamidreza Chitsaz

The year 2020 has seen an unprecedented COVID-19 pandemic due to the outbreak of a novel strain of coronavirus in 180 countries. In a desperate effort to discover new drugs and vaccines for COVID-19, many scientists are working around the…

Information Retrieval · Computer Science 2020-04-07 Sabber Ahamed , Manar Samad

The article explores different deep convolutional neural network architectures trained and tested on posteroanterior chest X-rays of 327 patients who are healthy (152 patients), diagnosed with COVID-19 (125), and other types of pneumonia…

Image and Video Processing · Electrical Eng. & Systems 2020-05-05 Pierre G. B. Moutounet-Cartan

In the research, we developed a computer vision solution to support diagnostic radiology in differentiating between COVID-19 pneumonia, influenza virus pneumonia, and normal biomarkers. The chest radiograph appearance of COVID-19 pneumonia…

Image and Video Processing · Electrical Eng. & Systems 2021-12-15 Julianna Antonchuk , Benjamin Prescott , Philip Melanchthon , Robin Singh

The outbreak of novel coronavirus disease (COVID- 19) has claimed millions of lives and has affected all aspects of human life. This paper focuses on the application of deep learning (DL) models to medical imaging and drug discovery for…

Image and Video Processing · Electrical Eng. & Systems 2021-07-21 Subrato Bharati , Prajoy Podder , M. Rubaiyat Hossain Mondal , V. B. Surya Prasath

The advent of high--throughput transcription profiling technologies has enabled identification of genes and pathways associated with disease, providing new avenues for precision medicine. A key challenge is to analyze this data in the…

Quantitative Methods · Quantitative Biology 2019-01-11 Sahil D. Shah , Rosemary Braun

Motivation: Drug repurposing is a viable solution for reducing the time and cost associated with drug development. However, thus far, the proposed drug repurposing approaches still need to meet expectations. Therefore, it is crucial to…

Machine Learning · Computer Science 2024-05-21 Ali Gharizadeh , Karim Abbasi , Amin Ghareyazi , Mohammad R. K. Mofrad , Hamid R. Rabiee

The objective of this research is to introduce a network specialized in predicting drugs that can be repurposed by investigating real-world evidence sources, such as clinical trials and biomedical literature. Specifically, it aims to…

Artificial Intelligence · Computer Science 2024-06-28 Ahmed Abdeen Hamed , Tamer E. Fandy

The pharmaceutical Research and development (R&D) process is lengthy and costly, taking nearly a decade to bring a new drug to the market. However, advancements in biotechnology, computational methods, and machine learning algorithms have…

Biomolecules · Quantitative Biology 2024-01-24 Damilola Oshunyinka

The availability of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) virus data post-COVID has reached exponentially to an enormous magnitude, opening research doors to analyze its behavior. Various studies are conducted by…

Neural and Evolutionary Computing · Computer Science 2025-01-28 Taslim Murad , Prakash Chourasia , Sarwan Ali , Imdad Ullah Khan , Murray Patterson

The aim of the work is to use deep neural network models for solving the problem of image recognition. These days, every human being is threatened by a harmful coronavirus disease, also called COVID-19 disease. The spread of coronavirus…

Machine Learning · Computer Science 2020-10-12 Samir S. Yadav , Jasminder Kaur Sandhu , Mininath R. Bendre , Pratap S. Vikhe , Amandeep Kaur

With worldwide concerns surrounding the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), there is a rapidly growing body of literature on the virus. Clinicians, researchers, and policy-makers need a way to effectively search…

Information Retrieval · Computer Science 2020-08-04 Sean MacAvaney , Arman Cohan , Nazli Goharian
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